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Golgi trafficking controlled by G-proteins

Dr. Brilliant no comments

The study is reported online April 9 in Developmental Cell. “Our work provides the first direct evidence that G proteins are signaling on membranes inside cells, not just at the cell surface as has been widely believed for several decades,” said Pradipta Ghosh, MD, associate professor and senior author…

Metabolic ‘reprogramming’ by p53 gene family leads to tumor regression

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The University of Texas MD Anderson Cancer Center investigation showed that, in vivo, the genes p63 and p73 can be manipulated to upregulate or increase levels of IAPP, a protein important for the body’s ability to metabolize glucose. IAPP is found in some diabetes drugs already on the market. The research findings were published in today’s issue of Nature. …

New target for kidney cancer therapy found — ScienceDaily

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A membrane channel is a family of proteins that allows the movement of ions, water or other solutions to pass through the membrane. These findings are being published in the Nov. 10, 2014, edition of the journal Cancer Cell. …

Selenium effective treatment against breast cancer, study suggests — ScienceDaily

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Julian Spallholz, a professor of nutritional sciences at Texas Tech University, has studied the effects of selenium on several types of cancer. His research on attaching selenium to the leading clinical chemotherapeutic monoclonal antibody for a type of breast cancer shows it can more effectively kill the cancer cells, he reports…

Genetic signal prevents immune cells from turning against the body

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Now, scientists at the Salk Institute have discovered a key control mechanism on the peacekeeping cells that determine if they send a halt signal to the killer T cells. The new research, published today in Cell, could help develop treatments for autoimmune disorders as well as some types of cancer…

Aspirin: scientists believe cancer prevention benefits outweigh harms

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For the first time, scientists have reviewed all the available evidence from many studies and clinical trials assessing both the benefits and harms of preventive use of aspirin. Conclusions of the study are published in the leading cancer journal Annals of Oncology. …

New PET/CT scanner more patient friendly — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/04/140410194334.htm

Afatinib: Added benefit depends on mutation status — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/02/140219102323.htm

Better guidelines, coordination needed for prostate cancer specialists — ScienceDaily

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source : http://www.sciencedaily.com/releases/2013/12/131209143254.htm

Evidence of savings in accountable care organizations, cancer care

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Researchers from The Dartmouth Institute for Health Policy & Clinical Practice report that savings may be found in accountable care organizations (ACO) through reductions in hospitalizations. The analysis published in the December issue of the journal Healthcare provides the first empirical evidence on how the shared savings ACO model may affect the cost and experience of care for cancer patients. The researchers looked at the Physician Group Practice Demonstration, which ran from 2005 to 2010 in 10 physician groups, for the best current evidence on the likely effectiveness of accountable care organizations for Medicare beneficiaries…