The seven-year study began in 2007 and the findings revolutionized the standard protocol for patient management in NCCS with an attenuated-dose regimen of sunitinib for patients with mRCC. The new treatment regimen for sunitinib has been accepted by oncologists in Singapore. For the patients, this would mean an estimated 30 per cent reduction in fees because of the lower dosage. …
Their paper, “Interplay Between VEGF-A and cMET Signaling in Human Vestibular Schwannomas and Schwann Cells,” by Sonam Dilwali, B.S., Daniel Roberts, M.D., Ph.D., and Konstantina M. Stankovic, M.D., Ph.D., FACS, is online in the Feb. 20 issue of Cancer Biology and Therapy. …
For the study, which was published in Nature Communications, the group performed whole genomic sequencing on 30 individual tumors classified as liver cancer displaying a biliary phenotype. This type of cancer originates in the liver, but is different from hepatocellular carcinoma, the dominant form of primary liver cancer, and is generally more aggressive, with poorer prognosis. …
Each year, the American Cancer Society compiles the most recent data on cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute and the Centers for Disease Control and Prevention, and mortality data from the National Center for Health Statistics. The data are disseminated in two reports: Cancer Statistics 2015, published in CA: A Cancer Journal for Clinicians, and its companion, consumer-friendly publication, Cancer Facts & Figures 2015. The reports also estimate the number of new cancer cases and deaths expected in the United States in the current year. Largely driven by rapid increases in lung cancer deaths among men as a consequence of the tobacco epidemic, the overall cancer death rate rose during most of the 20th century, peaking in 1991. …
Prostate cancer is the most commonly diagnosed non-skin cancer in the United States, and it is second only to lung cancer as the leading cause of cancer deaths in American men. An estimated 233,000 new cases of prostate cancer will be diagnosed in the United States in 2014, and an estimated 29,000 will die of the disease. More than 2 million men are currently living with prostate cancer in the United States…
Prostate cancer is the most commonly diagnosed non-skin cancer in the United States, and it is second only to lung cancer as the leading cause of cancer deaths in American men. An estimated 233,000 new cases of prostate cancer will be diagnosed in the United States in 2014, and an estimated 29,000 will die of the disease. More than 2 million men are currently living with prostate cancer in the United States…
Lung cancer treatment and prognosis is critically dependent on accurate staging that takes into account the extent to which cancer has spread from the primary lung tumor to other locations. Examination of lymph nodes containing lung cancer cells that have spread can be done by surgical removal, historically the standard practice, or by using a less invasive more cost effective technique called endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). …
“The answer is that we really don’t know yet,” says Sonia Okuyama, MD, investigator at the CU Cancer Center and the paper’s first author. The small sample sizes of most studies, focus on non-Hispanic white patients (predominantly in breast cancer), varied design of the phone interventions offered, and lack of consistency in adhering to reporting guidelines means that despite a high number of published studies, few definitive findings are possible…
A connection between inflammation and cancer has been recognized for over a hundred years. This connection is particularly evident in colon carcinogenesis, because patients with IBD have a higher incidence of colon cancer than the general population. …
“We identified a mutation in recent H1N1 strains that allows viruses to avoid immune responses that are present in a large number of middle-aged adults,” said Scott Hensley, Ph.D., a member of Wistar’s Vaccine Center and an assistant professor in the Translational Tumor Immunology program of Wistar’s Cancer Center. Historically, children and the elderly are most susceptible to the severe effects of the influenza viruses, largely because they have weaker immune systems…