Tag Archive patients

Precision medicine for adrenal cancer, study suggests

Dr. Brilliant no comments

In a randomized phase 3 trial, adrenal cancer patients receiving the investigational drug linsitinib fared no better than patients receiving a placebo. But the researchers noticed a small subset of patients who had significant response and remained on the drug for an extended time. “While it was only a small subset of patients who responded to linsitinib, this remains very promising in the era of precision medicine,” says co-principle investigator Gary D. …

Scientists pioneer new drug regimen that reduces toxicities for renal cancer patients

Dr. Brilliant no comments

The seven-year study began in 2007 and the findings revolutionized the standard protocol for patient management in NCCS with an attenuated-dose regimen of sunitinib for patients with mRCC. The new treatment regimen for sunitinib has been accepted by oncologists in Singapore. For the patients, this would mean an estimated 30 per cent reduction in fees because of the lower dosage. …

Certain factors influence whether cancer patients involve family members in treatment decisions

Dr. Brilliant no comments

For the study, Gabriella Hobbs, MD, and Nancy Keating, MD, MPH, of Harvard Medical School, and their colleagues surveyed 5284 patients with a new diagnosis of lung or colon cancer, and asked participants how they involved their families in decisions about their care. Only 1.5 percent of patients reported family-controlled decisions. Among the remaining patients, 49.4 percent reported equally sharing decisions with family, 22.1 percent reported some family input, and 28.5 percent reported little or no input from their families. Non-English speaking Asian patients and Spanish-speaking Hispanic patients were more likely to report equally shared decisions with their families than other patients. …

Test predicts response to treatment for complication of leukemia stem cell treatment

Dr. Expert no comments

Patients with fatal blood cancers like leukemia often require allogenic stem cell SCT to survive. Donor stem cells are transplanted to a recipient, but not without the risk of developing GVHD, a life-threatening complication and major cause of death after SCT. The disease, which can be mild to severe, occurs when the transplanted donor cells (known as the graft) attack the patient (referred to as the host). …

Mutations prevent programmed cell death

Dr. Expert no comments

The scientists started analyzing samples of human mantle cell lymphoma in a bid to find errors in the DNA. They discovered a region that is mutated in almost 30 percent of patients…

Increased use of hypofractionated whole-breast irradiation for patients with early-stage breast cancer

Dr. Expert no comments

An analysis of randomized trials demonstrated that patients with early-stage breast cancer who are treated with breast-conserving surgery and adjuvant whole-breast irradiation have improved survival and a lower risk of tumor recurrence compared to patients who are not treated with radiation therapy. Patients are commonly treated with CF-WBI; however, several recent randomized trials[2-5] have confirmed that patients treated with HF-WBI have similar disease-free and overall survival rates as those treated with CF-WBI. CF-WBI delivers a total dose of 45-50 Gy in 25-28 daily fractions of 1.8-2.0 Gy over five to six weeks, while HF-WBI uses a shorter treatment course and a lower total dose and number of fractions, delivering a total dose of 39-42.5 Gy in 13-16 daily fractions of 2.5-3.2 Gy over three to five weeks. …

Physicians play critical role in ensuring bladder cancer patients understand link between smoking, their disease

Dr. Expert no comments

At least half of bladder cancer cases diagnosed in the United States are the result of cigarette smoking. …

Physicians play critical role in ensuring bladder cancer patients understand link between smoking, their disease — ScienceDaily

Dr. Expert no comments

At least half of bladder cancer cases diagnosed in the United States are the result of cigarette smoking. Bladder cancer is the second most common tobacco-related malignancy, a fact that is not well known even among bladder cancer surgeons, let alone the general public. Quitting smoking after cancer diagnoses can prolong survival, improve cancer prognoses, and decrease the risk of developing second cancers. …

Factors that may contribute to pancreatic cancer: New insight

Dr. Brilliant no comments

Pancreatic cancer is a stealthy cancer that is usually detected at very late stages and has a 5-year survival rate of less than 5 percent. …

One in three people with cancer has anxiety or other mental health challenges

Dr. Expert no comments

“These findings reinforce that, as doctors, we need to be very aware of signs and symptoms of mental and emotional distress. We must encourage patients to seek evaluation, support, and treatment if necessary as there are long-term risks often associated with more severe, untreated mental health disorders. This research also sheds light on which patients we should watch more closely,” said lead study author Anja Mehnert, PhD, a professor of psychosocial oncology at the University of Leipzig in Germany. “We also want to reassure patients who are struggling that they are not alone or unique, and that these mental and emotional challenges can be temporary, especially with effective psychological support or state-of-the-art mental health treatment.” Psychological support options may include individual, couples, family, and group psychotherapy, and relaxation therapy and imagery, among others, according to the authors…