Tag Archives: germany

Experts warn of stem cell underuse as transplants reach one million worldwide

HSCT (also known as blood and marrow transplant) is most often used to treat diseases of the blood and several types of cancer such as multiple myeloma or leukemia. For many people with these diseases the only possibility of a cure is to have a HSCT. The procedure provides healthy cells from either the patient (autologous transplantation) or from a healthy donor (allogeneic transplantation) to replace those lost to disease or chemotherapy…

Mammography screening: Patient pamphlets do not affect willingness to participate

In Germany, the invitation to undergo mammography screening that is sent to all women between the ages of 50 and 69 is accompanied by an information leaflet explaining the advantages and disadvantages of screening. In this issue of Deutsches �rzteblatt International, Elisabeth Gummersbach and colleagues report on a study in which they determined how well the prospective subjects understood the information presented and whether this information influenced their willingness to undergo screening. It was found that the leaflet itself made little or no difference to the women’s willingness to participate. Rather, the most important factor in the decision whether to be screened was usually a doctor’s personal recommendation…

One in three people with cancer has anxiety or other mental health challenges

“These findings reinforce that, as doctors, we need to be very aware of signs and symptoms of mental and emotional distress. We must encourage patients to seek evaluation, support, and treatment if necessary as there are long-term risks often associated with more severe, untreated mental health disorders. This research also sheds light on which patients we should watch more closely,” said lead study author Anja Mehnert, PhD, a professor of psychosocial oncology at the University of Leipzig in Germany. “We also want to reassure patients who are struggling that they are not alone or unique, and that these mental and emotional challenges can be temporary, especially with effective psychological support or state-of-the-art mental health treatment.” Psychological support options may include individual, couples, family, and group psychotherapy, and relaxation therapy and imagery, among others, according to the authors…

Many patients in cancer centers may not experience a dignified death

Previous research has shown that hospitals are often ill-prepared to provide care for dying patients. To investigate whether the circumstances for dying on cancer center wards allow for a dignified death, Karin Jors, MA, of the University Medical Center Freiburg, and her colleagues surveyed physicians and nurses in 16 hospitals belonging to 10 cancer centers in Baden-W�rttemberg, Germany. The survey addressed topics regarding end-of-life care including structural conditions such as rooms and staff, education/training, working environment, family/caregivers, medical treatment, communication with patients, and dignified death. Among 1131 survey respondents, 57 percent believed that patients could die with dignity on their ward. …

New antifungal as effective as existing drugs with fewer adverse events

“There is a growing need for new antifungal therapies like isavuconazole because serious fungal infections caused by Aspergillus and other molds are on the rise due to the increasing numbers of immunosuppressed patients, including those with active cancer. These infections are associated with high morbidity and mortality. If approved, isavuconazole has the potential to be an important new option for the treatment of these life-threatening fungal infections,” says Andrew Ullman of Julius Maximilians University in Wuerzburg, Germany, one of the researchers presenting data. Invasive fungal infections are important causes of morbidity and death for patients with hematological malignancies…

Cetuximab or bevacizumab with combi chemo equivalent in KRAS wild-type MCRC

“The CALGB/SWOG 80405 trial was designed and formulated in 2005, and the rationale was simple: we had new drugs –bevacizumab and cetuximab– and the study was designed to determine if one was better than the other in first-line for patients with colon cancer,” said lead study author Alan P. Venook, distinguished Professor of Medical Oncology and Translational Research at the University of California, San Francisco, USA. The CALGB/SWOG 80405 trial studied patients whose tumours were KRAS wild-type at codons 12 and 13. …