Tag Archives: cancer

Small cancer risk following CT scans in childhood and adolescence confirmed

CT (computed tomography) scans have great medical benefits, but their increasing use since the 1980s has raised some concerns about possible cancer risks, particularly following exposures in childhood. Most previous studies have estimated risks indirectly, and some radiation experts have questioned the validity of these estimates. There is currently much uncertainty and as such, researchers from Australia and Europe carried out a study comparing cancer rates in patients exposed to CT scans at ages 0-19 years compared with unexposed persons of a similar age. All participants were born between 1985 and 2005 with total follow-up ending at the end of 2007. …

Inexpensive, accurate way to detect prostate cancer: At-home urine tests

After more than a decade of work, UC Irvine chemists have created a way to clearly identify clinically usable markers for prostate cancer in urine, meaning that the disease could be detected far sooner, with greater accuracy and at dramatically lower cost. The same technology could potentially be used for bladder and multiple myeloma cancers, which also shed identifiable markers in urine. "Our goal is a device the size of a home pregnancy test priced around $10…

Antidepressants may help with heart disease

For some patients with heart disease, taking antidepressants may reduce the risk of heart problems brought on by mental stress, a new study suggests. Researchers looked at patients with myocardial ischemia a condition in which the heart doesn't get enough blood as they preformed mentally stressful activities. All of the patients also had coronary heart disease, or a narrowing of the arteries that supply blood to the heart. Patients in the study who took the antidepressant escitalopram (sold as Lexapro) were about 2.5 times less likely than those who took a placebo to experience myocardial ischemia triggered by mental stress. The findings suggest that an antidepressant, or other treatments that help patients cope with stress, could improve symptoms for some people with coronary heart disease, said study researcher Dr. Wei Jiang, an associate professor of psychiatry and behavioral sciences at Duke University School of Medicine. However, future studies are needed to confirm the results, and to identify the people most likely to benefit from such treatment, Jiang said. Stress and the heart About 30 years ago, doctors observed that mental stress could bring on myocardial ischemia.tudies also have found that people with mental-stress-induced myocardial ischemia are at increased risk of dying from heart disease. Coronary heart disease is the leading cause of death in the United States and about 50 percent of patients with the condition experience mental-stress-induced myocardial ischemia yet few studies have attempted to find treatments. In the new study, 127 patients were randomly assigned to receive escitalopram or placebo for six weeks. Participants completed a number of tests at the beginning and end of the study, including a treadmill stress test, a math test and a test in which participants told a sad story in order to evoke emotion. During the tests, the researchers examined certain heart symptoms to diagnose myocardial ischemia, such as a reduction in blood pumped out of one of the heart's cambers. After six weeks, about 34 percent of participants taking the antidepressant did not experience myocardial ischemia during the mental-stress tests, compared with 17 percent in the placebo group. The antidepressant did not affect whether patients experienced myocardial ischemia during exercise. Dr. Andrew Freeman, a cardiologist at the National Jewish Health hospital in Denver, said it was not very surprising that drugs that blunt the brain's response to stress would also blunt the heart's response to stress. But what the findings mean for patients in the long term is not known, said Freeman, who was not involved in the study. Future studies are needed to see whether antidepressants might reduce the risk of cardiovascular events like heart attacks, Freeman said. How does it work?

New drug could reduce asthma attacks by 87 percent

An experimental drug being developed by Regeneron Pharmaceuticals Inc. and Sanofi SA showed promising results during a small, mid-stage clinical trial in treating a subset of patients with moderate to severe asthma, but some physicians cautioned that it was too early to say how effective the treatment may ultimately be. The drug, dupilumab, is considered one of Regeneron's most promising pipeline drugs and could eventually reach $750 million in annual U.S. sales if it gains U.S. approval to treat asthma, according to Barclays. Regeneron and Sanofi, which have a partnership to co-develop certain experimental drug programs, are also testing the drug to treat a type of eczema, the itchy skin condition, and have said dupilumab could eventually be applied to other allergic conditions. Results from the trial, published online Tuesday in the New England Journal of Medicine, showed that dupilumab reduced asthma attacks by 87 percent in patients taking the drug compared to those receiving a placebo. Side effects of the drug appeared to be relatively consistent with those of patients taking placebos. “It really raises the possibility that we've hit upon a fundamental pathway that's driving the allergic reaction in asthma,” said George D. Yancopoulos, Regeneron's chief scientific officer, in an interview. However, the trial was relatively small, enrolling 52 patients in each of the study's two treatment groups. An editorial accompanying the study results said the trial design, in which patients were gradually weaned off of standard therapies for asthma, did not reflect a “real world” environment. It's also unclear how large a swath of asthma patients will benefit from the drug, because only those with higher-than-normal disease-fighting white blood cells were admitted to the study, Michael E. Wechsler, director of the asthma program at National Jewish Health, a Denver-based research hospital that specializes in respiratory conditions, wrote in the editorial. Just 21 percent of patients screened for the trial met the inclusion criteria, Dr. Wechsler wrote. Asthma affects more than 24 million people in the U.S., but existing therapies are unable to control the condition for as many as 10 percent to 20 percent of patients, according to the study's authors. Click for more from The Wall Street Journal.source : http://www.foxnews.com/health/2013/05/22/new-drug-could-reduce-asthma-attacks-by-87-percent/

Cannabis use associated with lower blood sugar

A new study published in the American Journal of Medicine has revealed a potential benefit from the use of cannabis. The article, entitled “The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among U.S. Adults,” investigated the blood sugar-related effects of cannabis use among participants in the National Health and Nutrition Examination Survey from 2005 to 2010. In several other studies of large populations, lower rates of both obesity and diabetes have been noted among users of cannabis, as compared with non-users. This curious fact encouraged the three primary authors of the study to examine cannabis use among the 4657 participants in the national survey. The researchers noted that although cannabis smokers generally consume more calories than non-users, they paradoxically live with lower body mass indexes (BMIs) and reduced rates of both obesity and diabetes. Of the participants in the national survey, 579 were currently using cannabis and 1975 had previously used cannabis. To assess blood glucose, insulin resistance and other factors among cannabis users, the authors organized survey participants into three groups – those who had never used cannabis, those who had used cannabis but not within 30 days, and those who were current users. The authors put study participants through tests for fasting blood sugar levels, high density lipoprotein cholesterol (HDL-C) testing, and assessments of blood pressure, BMI and waist circumference. The researchers found that subjects who were current cannabis users had lower levels of fasting insulin, lower levels of insulin resistance, smaller waist circumference, and higher levels of HDL cholesterol, which is known to reduce the risk of cardiovascular disease. This supported findings from earlier studies in which cannabis users showed improved weight, improved insulin resistance, and reduced incidence of diabetes, as compared with non-users. While the potential relationship between cannabis and improved body mass and blood sugar has yet to be fully understood, it is believed that cannabis acts on the cannabinoid 1 and 2 receptors in the brain, enhancing the activity of adiponectin. This hormone helps to regulate blood sugar and plays a role in controlling weight and reducing the tendency toward diabetes.   Cannabis is the most widely used illicit drug in the United States, with approximately 17 million regular users. Medical marijuana has been legalized in 19 states plus the District of Columbia, and two states, Colorado and Washington, have legalized cannabis outright. A number of states have effectively decriminalized the possession of small quantities of cannabis and its use. This fundamental shift in legal status has drawn more researchers to investigate cannabis for any possible health benefits. This study strikes at the heart of two major epidemics: obesity and diabetes. Based on results reported in this study and supported by other epidemiological surveys, it is possible that cannabis use helps to reduce the tendency toward both obesity and type 2 diabetes. Thus, the substance that induces “the munchies” may hold hope for two epidemic diseases arising from overeating.Chris Kilham is a medicine hunter who researches natural remedies all over the world, from the Amazon to Siberia. He teaches ethnobotany at the University of Massachusetts Amherst, where he is Explorer In Residence. Chris advises herbal, cosmetic and pharmaceutical companies and is a regular guest on radio and TV programs worldwide. His field research is largely sponsored by Naturex of Avignon, France. Read more at& MedicineHunter.com.source : http://www.foxnews.com/health/2013/05/22/cannabis-use-associated-with-lower-blood-sugar/

Foster Farms recalls grilled chicken breast strips for containing allergens

SAN FRANCISCO – & California-based chicken producer Foster Farms is recalling about 6,165 pounds of its ready-to-eat grilled chicken breast strips because the strips contain wheat and soy -- known allergens -- which are not listed on the labels of its packages, federal agriculture officials said. The mislabeled packages were discovered when a customer complained, the U.S. Department of Agriculture's Food Safety and Inspection Service said in announcing the recall Tuesday. The problem occurred when labels for another chicken product that does not contain wheat or soy were inadvertently used, food safety inspectors and officials at Foster Farms said. There have been no reports of adverse reactions from the sale of the mislabeled products, officials said. The chicken breast strips being recalled were sold in 4.5-pound cases containing 12, 6-ounce trays of “Foster Farms Grilled Chicken Breast Strips Boneless & Skinless With Rib Meat 97% Fat Free,” with an identifying case code of “000606.” The recalled product bears the establishment number “P-20923” inside the USDA mark of inspection and a use-by date of “JUN 22 2013” printed on each tray. They were produced April 23 and were distributed to retailers in Arizona, California, Hawaii, Nevada, Oregon, Utah and Washington. Based in Porterville, Foster Farms is a family-owned company that has been operating since 1939, according to the company's website. In a statement, Fosters Farms spokeswoman Lorna Bush said “food safety is, and always has been, our top priority.”source : http://www.foxnews.com/health/2013/05/22/foster-farms-recalls-grilled-chicken-breast-strips-for-containing-allergens/

Changing cancer’s environment to halt its spread

The study team, led by Randolph Watnick, PhD, at Boston Children’s Hospital, Vivek Mittal, PhD, at Weill Cornell Medical College and Lars Akslen, MD, PhD, at the University of Bergen, released their findings in the May issue of the journal Cancer Discovery. The main cause of cancer mortality is not the primary tumor itself, but rather its spread — metastasis — to other locations in the body and subsequent organ failure. Previous studies by Watnick, a member of Boston Children’s Vascular Biology Program, and others have shown that tumors capable of metastasis release proteins that help prepare new homes in distant organs for their metastatic progeny. …

Cancer and birth defects in Iraq: The nuclear legacy

The radioactive element uranium is widely dispersed throughout Earth’s crust and is much sought after as a fuel for nuclear power plants and for use in weapons. Depleted uranium (DU), commonly used in modern munitions such as defensive armour plating and armour-piercing projectiles, is 40 per cent less radioactive than natural uranium, but remains a significant and controversial danger to human health. The World Health Organisation (WHO) sets a maximum uranium exposure of 1 millisievert (mSv) per year for the general public, but environmental scientists at the University of Mosul and the Institute of Forest Ecology, Universitaet für Bodenkultur (BOKU), Vienna, Austria, led by Riyad Abdullah Fathi have measured significant levels of uranium in soil samples from three sites in the province of Nineveh in the north of Iraq. Writing in the journal Medicine, Conflict and Survival, Fathi and colleagues link their findings with dramatic increases in cancers reported to the Mosul Cancer Registry and the Iraqi national cancer registry (which began collecting data in 1975)…

New tumor-killer shows great promise in suppressing cancers

This molecule is based on a natural protein present in human breast milk, which has been found to have strong and wide-ranging tumour killing properties when bound to certain lipids. Lipids are organic molecules like amino acids and carbohydrates, made up of carbon and hydrogen, and help to store energy and to form biological membranes. …