Tag Archive france

Promising results shown with targeted approaches in subsets of non-small cell lung cancer

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“Reports of lung cancers bearing mutations in BRAF have generated considerable interest because these mutations may be associated with increased sensitivity to BRAF tyrosine-kinase inhibiting agents,” says lead author Dr David Planchard, pulmonary oncologist at the Gustav-Roussy Cancer Campus, Paris, France. Planchard says studies suggest that activating BRAF mutations are present in around 2% of lung carcinomas — approximately 80% of which are V600E mutations. The BRAF V600E mutations are frequently associated with shorter disease-free, overall survival, and lower response rates to platinum-based chemotherapy. …

Skin pigment renders sun’s UV radiation harmless using projectiles

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In a new study, the team from Lund University, working with colleagues in France and Italy, have studied pigment in the skin and its building blocks. …

Rates of heart disease, stroke continue to decline in Europe

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The research, which provides an update for 2014 on the burden of cardiovascular disease (CVD) in Europe, shows that death rates from CVD (diseases of the heart and blood vessels) vary enormously. For some eastern European countries, including Russia and Ukraine, the death rate from coronary heart disease for 55-60 year olds is greater than the equivalent rate in France for people 20 years older. The age adjusted CVD death rates for men and women of all ages were six-fold higher in Russia than in France. In 2010 in Russia 915 men and 517 women died per 100,000 of the population, whereas the equivalent rates in France were 150 and 87 per 100,000 respectively. …

Postmenopausal breast cancer risk decreases rapidly after starting regular physical activity — ScienceDaily

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“Twelve MET-h [metabolic equivalent task-hours] per week corresponds to walking four hours per week or cycling or engaging in other sports two hours per week and it is consistent with the World Cancer Research Fund recommendations of walking at least 30 minutes daily,” said Agn├Ęs Fournier, PhD, a researcher in the Centre for Research in Epidemiology and Population Health at the Institut Gustave Roussy in Villejuif, France. “So, our study shows that it is not necessary to engage in vigorous or very frequent activities; even walking 30 minutes per day is beneficial.” Postmenopausal women who in the previous four years had undertaken 12 or more MET-h of physical activity each week had a 10 percent decreased risk of invasive breast cancer compared with women who were less active. Women who undertook this level of physical activity between five and nine years earlier but were less active in the four years prior to the final data collection did not have a decreased risk for invasive breast cancer. “Physical activity is thought to decrease a woman’s risk for breast cancer after menopause,” said Fournier…

Prostate cancer screening reduces deaths by a fifth: Large, long-term European trial

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Despite this new evidence for the effectiveness of prostate-specific antigen (PSA) testing to reduce mortality, doubts as to whether the benefits of screening outweigh the harms remain, and routine PSA screening programmes should not be introduced at this time, conclude the authors. The European Randomised study of Screening for Prostate Cancer (ERSPC) began in 1993 to determine whether screening men for PSA reduces deaths from prostate cancer. …

Diets rich in antioxidant resveratrol fail to reduce deaths, heart disease or cancer — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/05/140512214128.htm

‘Remodelling’ damaged nuclei: Discovery could lead to new treatments for accelerated aging disease — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/05/140501142221.htm

Six months hormonal treatment in addition to radiotherapy improves survival for men with localized prostate cancer — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/04/140406214415.htm

Deaths from breast cancer fall in Europe, but unexplained differences between countries remain — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/03/140320101112.htm

Preventive ovarian surgery should be performed early for greatest benefit; substantial mortality risk reduction found — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/02/140224171145.htm