Tag Archives: social

Potential new target to treat malignant pleural mesothelioma

In the September issue of the International Association for the Study of Lung Cancer’s journal, the Journal of Thoracic Oncology (JTO), researchers conclude that Ephrin (EPH) B2 seems to play an important role in malignant pleural mesothelioma cell lines and tumors. Using expression arrays, researchers from the New York University Langone Medical Center looked at EPHB2 in 34 malignant pleural mesothelioma tumors , and found it significantly elevated in tumor tissue compared with matched normal peritoneum. They found EPHB2 overexpressed in all malignant pleural mesothelioma cell lines, but not in benign mesothelial cells…

People who eat nuts more than three times a week have reduced risk of dying from cancer or cardiovascular disease

The PREDIMED nutrition trial based in Spain looked at the effect on the primary prevention of cardiovascular disease of over 7000 older people (aged 55 to 90) randomized to a Mediterranean Diet supplemented with extra virgin olive oil or nuts, compared to a control group following a low fat diet. In Mediterranean regions, nut consumption is relatively high compared to other countries…

Ground-breaking new method of ‘starving’ cancer cells

Chris Proud, Professor of Cellular Regulation in Biological Sciences at the University of Southampton says: "Cancer cells grow and divide much more rapidly than normal cells, meaning they have a much higher demand for and are often starved of, nutrients and oxygen. We have discovered that a cellular component, eEF2K, plays a critical role in allowing cancer cells to survive nutrient starvation, whilst normal, healthy cells do not usually require eEF2K in order to survive. Therefore, by blocking the function of eEF2K, we should be able to kill cancer cells, without harming normal, healthy cells in the process." Almost all cells in the human body contain the same basic components, meaning that to attack one of them in a cancer cell, that component will also be affected in normal cells…

Men say they want prostate cancer test, despite risks

The U.S. Preventive Services Task Force (USPTF) recommends that middle-aged men not receive the prostate-specific antigen test (PSA) because research has shown that the benefits of testing do not outweigh the risks, which include false positive results. More than three quarters of the men who participated in the survey said they were not aware of the new recommendation, said Linda Squiers, Ph.D., senior health communication scientist at RTI International in Rockville, MD, and lead author of the study…

Facebook helped boost organ donor registration

Raising awareness of organ donation on social media websites can help boost donation rates, according to a new study. Facebook began allowing users to make their status as organ donors visible in their profiles in May 2012, and on the first day of the change, about 13,000 people in the U.S. registered to become organ donors 20 times more than the average number of daily registrations. The effect of the social media initiative on its first day varied across states, ranging from a seven-fold increase in registrations in Michigan, to 100-fold increase in Georgia, the results showed. The findings mean that social media might be an effective tool for encouraging organ donation, as well as tackling other public health problems in which communication and education are essential, the researchers said. Our research speaks to on-going efforts to address the organ availability crisis in the United States. It also suggests that social media and social networks may be valuable tools in re-approaching refractory public health problems, said study researcher Dr. Andrew Cameron, the surgical director of liver transplantation at Johns Hopkins Hospital in Baltimore. Today, more than 118,500 people in the U.S. are on the waiting list for organs, and one name is added to the list every ten minutes, according to the United Network for Organ Sharing. On average, 18 people die every day waiting for an organ. Despite countless previous efforts, organ donation rates in the United States have not grown, while need for transplants has risen dramatically. Therefore, new efforts are needed to boost organ donation through public education, the researchers said. The Facebook initiative t let users add their organ-donation status to the timeline for their friends and family to see. It also directed people to the official organ donation registry websites of their states. The results showed high registration rates following the Facebook initiative, compared with usual rates at the Department of Motor Vehicles (DMV). The boost may stem from the fact that people are more open to making decisions about sensitive and difficult topics when they are in an environment “amongst friends,” compared with the environment at the DMV, the researchers said. However, after the initial spike, registration rates diminished over the following weeks. The researchers said this shows more work is needed to find ways to sustain the increase. “The next challenge for efforts like the organ donor initiative will be utilization of social media applications like Facebook, Twitter, YouTube or Instagram more effectively and more durably,” the researchers wrote in the study, which was published today (June 18) in the American Journal of Transplantation. Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.source : http://www.foxnews.com/health/2013/06/18/facebook-helped-boost-organ-donor-registration/

Can a common hormone prevent unborn babies from developing autism?

Fetal alcohol spectrum disorder (FASD) and autism spectrum disorder (ASD), both conditions that are neurodevelopmental in origin, may share some similar molecular vulnerabilities, according to a new rodent study published in Alcoholism: Clinical & Experimental Research. When researchers from Northwestern Medicine in Chicago, Ill., exposed pregnant rats to alcohol, they found their offspring experienced symptoms of social impairment and altered-levels of genes that have been previously linked to autism in humans. “The novel finding here is that these two disorders share molecular vulnerabilities, and if we understand those, we are closer to finding treatments,” Eva Redei, the senior author of the study and professor of psychiatry and behavioral sciences at Northwestern University Feinberg School of Medicine, said in a press release. Furthermore, study authors found that when the pregnant, alcohol-exposed rats were given low doses of the thyroid hormone thyroxin, they were able to lessen some of the effects of alcohol damage and reverse the expression of autism-related genes in offspring. Though more research needs to be done, Dr. Manny Alvarez, senior managing health editor for FoxNews.com, hopes these findings will lead researchers to explore the potential for thyroxin to be utilized in patients who are at risk for having an autistic child. “We’re still poor at identifying patients at risk for autism, but now we now there is family history, sibling history and some genetic deletions strongly associated with autism,” Alvarez said. “One could argue that perhaps in patients at risk for having an autistic child, after more human studies, the prophylactic use of thyroxin can help prevent the neural behavioral changes of autism.”source : http://www.foxnews.com/health/2013/06/14/link-between-fetal-alcohol-syndrome-and-autism-spectrum-disorder-may-point-to/

Chemotherapy: Greater potential benefit in overall survival for eribulin compared with capecitabine

The specific patient populations who appeared to benefit from eribulin, in comparison to capecitabine, are as follows: Patients with more than two organs involved with metastatic breast cancer Patients who had not received chemotherapy for six months or longer Patients who had received anthracycline and/or a taxane therapies in the metastatic setting Previous pre-specified exploratory analysis of overall survival and progression-free survival showed women with triple-negative, ER-negative, HER2-negative also had a greater relative benefit in overall survival with eribulin over capecitabine. …