Tag Archive georgia

How breast cancer cells break free to spread in body

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A gene normally involved in the regulation of embryonic development can trigger the transition of cells into more mobile types that can spread without regard for the normal biological controls that restrict metastasis, the new study shows. Analysis of downstream signaling pathways of this gene, called SNAIL, could be used to identify potential targets for scientists who are looking for ways to block or slow metastasis. “This gene relates directly to the mechanism that metastatic cancer cells use to move from one location to another,” said Michelle Dawson, an assistant professor in the School of Chemical and Biomolecular Engineering at the Georgia Institute of Technology…

62% of colorectal cancer patients report financial burden from treatment, study finds

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The burden was greatest among patients who received chemotherapy and among younger patients who worked in low-paying jobs. The study surveyed 956 patients who had been treated for stage 3 colorectal cancer. Among this group, chemotherapy is known to increase survival by up to 20 percent and is routinely recommended following surgery. …

New treatment target identified for aggressive breast cancer — ScienceDaily

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The gene ErbB2, commonly called HER2, is highly expressed in about 25 percent of breast cancers. Scientists have now found the protein Erbin, thought to be an anti-tumor factor, also is highly expressed in these cancers and essential to ErbB2’s support of breast cancer. When scientists interfere with the interaction between the two in mice, it inhibits tumor development and the usual spread to the lungs, according to an international team reporting in the journal PNAS. The team documented the overexpression of both in 171 cases of mostly aggressive human breast cancer as well. …

Fundamental theory about education of immune police questioned by researchers

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It’s known that stem cells come out of the bone marrow and travel to the tiny thymus gland behind the breastbone to learn to become one of two CD4T cell types: one leads an attack, the other keeps the peace. One widely held concept of why they become one or the other is that, despite coming from the same neighborhood and going to the same school, they are exposed to different things in the thymus, said Dr. Leszek Ignatowicz, immunologist at the Medical College of Georgia at Georgia Regents University. In this case, the “things” are ligands and developing T cells are potentially exposed to thousands of these tiny pieces of us inside the thymus…

Protein appears to protect against bone loss in arthritis

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Arthritis as well as aging prompt the body to make more fat than bone, and the researchers have previously shown GILZ can restore a more youthful, healthy mix. It also tamps down inflammation, a major factor in arthritis…

Wide variation in lung cancer rates globally, study finds — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/05/140516111005.htm

Decreasing chemoresistance in ovarian cancer — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/05/140502130114.htm

New approach to leukemia testing may better define prognosis, treatment — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/03/140329175116.htm

Function of cancer-causing gene explored by researchers — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/03/140326182240.htm

Potential options for attacking stem cells in triple-negative breast cancer — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/02/140217084802.htm