Tag Archives: gen

Breast reconstruction using patient’s own tissues yield higher satisfaction rates — ScienceDaily

But the findings may at least partly reflect differences in the characteristics of women choosing different options for breast reconstruction, according to the study by plastic surgeon Dr. Yassir Eltahir and colleagues of University Medical Center Groningen, the Netherlands. Higher Satisfaction Score with Autologous Breast Reconstruction The researchers used the recently developed “BREAST-Q” questionnaire to analyze patient satisfaction and quality of life after breast reconstruction. …

Potential target for treating triple-negative breast cancer identified

So-called “triple-negative” breast cancer represents between 12 and 17 percent of all breast cancers. It derives its name from the lack of receptors for estrogen, progesterone and Her2. The absence of these receptors rules out proven hormone therapies such as tamoxifen. …

Diverse gut bacteria associated with favorable ratio of estrogen metabolites

Since the 1970s, it has been known that in addition to supporting digestion, the intestinal bacteria that make up the gut microbiome influence how women’s bodies process estrogen, the primary female sex hormone. The colonies of bacteria determine whether estrogen and the fragments left behind after the hormone is processed continue circulating through the body or are expelled through urine and feces. Previous studies have shown that levels of estrogen and estrogen metabolites circulating in the body are associated with risk of developing postmenopausal breast cancer…

Diverse gut bacteria associated with favorable ratio of estrogen metabolites — ScienceDaily

Ovarian cancer treatment discovered by researchers

Trebananib (formally known as AMG 386; Amgen) is a first-in-class peptide-Fc fusion protein (or peptibody) that targets angiogenesis (the growth of new blood vessels into cancerous tumors) by inhibiting the binding of both angiopoietin 1 and 2 to the Tie2 receptor. This is very different mechanism of action than other agents that also effect angiogenesis by inhibiting vascular endothelial growth factor (VEGF) such as bevacizumab (Avastin; Genentech). Trebananib does not increase the risks of hypertension (high blood pressure) and bowel perforation like bevaciuzmab, but still has a similar impact on tumor shrinkage and delaying cancer progression…

Plasma tool for destroying cancer cells — ScienceDaily

source : http://www.sciencedaily.com/releases/2014/03/140325094818.htm

New technology detects cellular memory, aids in understanding of how diseases such as cancer arise — ScienceDaily

source : http://www.sciencedaily.com/releases/2014/02/140224110144.htm

Test developed to assess effect of more than 1,500 chemicals on estrogen — ScienceDaily

source : http://www.sciencedaily.com/releases/2014/02/140218142358.htm

Protecting the Skin From Sun Exposure — ScienceDaily

source : http://www.sciencedaily.com/releases/2014/01/140127122146.htm

Computer simulation of blood vessel growth

"Better understanding of the processes that regulate the growth of blood vessels puts us in a position ultimately to develop new treatments for diseases related to blood vessel growth," and to better understand cancer metastasis, says bioengineering professor Jeff Weiss of the university’s Scientific Computing and Imaging Institute. Weiss and Lowell Edgar, a postdoctoral fellow in bioengineering, published their study Wednesday, Jan. 22, in the Public Library of Science’s online journal PLOS ONE. …