Researchers led by LMU’s Professor Angelika Vollmar and Professor Stephan Sieber of the Technische Universit�t M�nchen have identified a class of chemicals that represent a potential new weapon in the fight against malignant tumors. The compound is itself non-toxic, but it stimulates the killing of rapidly dividing cells by chemotherapeutic drugs. …
“This study shows that a single receptor may play various roles depending on whether its site of action is in the nucleus or on the cell membrane,” states Dr. Jean-S�bastien Joyal, MD, PhD, a pediatric intensivist at the Sainte-Justine UHC and an assistant professor at the Universit� de Montr�al. The groundbreaking discovery has significant clinical implications, since many drugs act on this family of receptors irrespective of their site of action in the cell. “Our results are extremely encouraging. …
Now a team of scientists, led by Prof. Taeghwan Hyeon at the Institute for Basic Science (IBS)/Seoul National University and Prof. …
In a study published last year, the group succeded in eradicating lung tumors in transgenic mice by adopting the same strategy involving the expression of Omomyc, a Myc inhibitor designed by Soucek. They also confirmed that there were no side effects post-administration of repeated and long-term treatment. Importantly, there was no evidence of resistance to therapy — one of the greatest challenges in the treatment of cancer. …
Researchers from the University of São Paulo (USP) have identified an RNA known as INXS that, although containing no instructions for the production of a protein, modulates the action of an important gene in the process of apoptosis, or programmed cell death. …
source : http://www.sciencedaily.com/releases/2014/06/140627113054.htm
source : http://www.sciencedaily.com/releases/2014/06/140624105237.htm
source : http://www.sciencedaily.com/releases/2014/05/140521094958.htm
source : http://www.sciencedaily.com/releases/2014/04/140405233847.htm
source : http://www.sciencedaily.com/releases/2014/04/140401112113.htm