Tag Archives: united

Breast cancer specialist reports advance in treatment of triple-negative breast cancer

“Impact of the Addition of Carboplatin and/or Bevacizumab to Neoadjuvant Once-Per-Week Paclitaxel Followed by Dose-Dense Doxorubicin and Cyclophosphamide on Pathologic Complete Response Rates in Stage II to III Triple-Negative Breast Cancer: CALGB 40603 (Alliance)” was accepted as a rapid publication and published online this month by the Journal of Clinical Oncology. It will come out in print in September. Because of its rapid growth rate, many women with triple-negative breast cancer receive chemotherapy to try to shrink it before undergoing surgery. …

Knowledge is power: Men who are uneducated about their prostate cancer have difficulty making good treatment choices — ScienceDaily

UCLA researchers found that men who aren’t well educated about their disease have a much more difficult time making treatment decisions, called decisional conflict, a challenge that could negatively impact the quality of their care and their long-term outcomes. …

Knowledge is power: Men who are uneducated about their prostate cancer have difficulty making good treatment choices

UCLA researchers found that men who aren’t well educated about their disease have a much more difficult time making treatment decisions, called decisional conflict, a challenge that could negatively impact the quality of their care and their long-term outcomes. …

U.S. has seen widespread adoption of robot-assisted cancer surgery to remove the prostate

In 2001, surgeons began using robotic technologies in operations to remove the prostate. To examine trends in the use of such robotic-assisted radical prostatectomy (RARP) procedures for prostate cancer patients, Steven Chang, MD, MS, of Harvard Medical School, the Dana-Farber Cancer Institute, and Brigham and Women’s Hospital, led a team that analyzed 489,369 men who underwent non-RARP (i.e., open or laparoscopic radical prostatectomy) or RARP in the United States from 2003 to 2010. During the study period, RARP adoption (defined as performing more than 50 percent of annual radical prostatectomies with the robotic approach) increased from 0.7 percent to 42 percent of surgeons performing radical prostatectomies. Surgeons who performed at least 25 radical prostatectomies each year were more likely to adopt RARP…

New mouse model points to therapy for liver disease

Development of effective new therapies for preventing or treating NASH has been stymied by limited small animal models for the disease. In a paper published online in Cancer Cell, scientists at the University of California, San Diego School of Medicine describe a novel mouse model that closely resembles human NASH and use it to demonstrate that interference with a key inflammatory protein inhibits both the development of NASH and its progression to liver cancer. “These findings strongly call for clinical testing of relevant drugs in human NASH and its complications,” said senior author Michael Karin, PhD, Distinguished Professor of Pharmacology in UC San Diego’s Laboratory of Gene Regulation and Signal Transduction. “Our research has shown that, at least in this mouse model, chemical compounds that include already clinically approved drugs that inhibit protein aggregation can also be used to prevent NASH caused by a high fat diet.” The increasing prevalence of NAFLD is linked to the nation’s on-going obesity epidemic. …

Prostate cancer diagnosis improves with MRI technology — ScienceDaily

An ultrasound machine provides an imperfect view of the prostate, resulting in an under-diagnosis of cancer, said J. Kellogg Parsons, MD, MHS, the UC San Diego Health System urologic oncologist who, along with Christopher Kane, MD, chair of the Department of Urology and Karim Kader, MD, PhD, urologic oncologist, is pioneering the new technology at Moores Cancer Center. “With an ultrasound exam, we are typically unable to see the most suspicious areas of the prostate so we end up sampling different parts of the prostate that statistically speaking are more likely to have cancer,” said Parsons, who is also an associate professor in the Department of Urology at UC San Diego School of Medicine. “The MRI is a game-changer…

U.S. lung cancer rates vary by subtype, sex, race/ethnicity, and age

Overall, lung cancer rates are declining in the United States, but little is known about trends related to different subtypes of lung cancer and different demographic groups. To investigate, Denise Riedel Lewis, PhD, MPH, of the National Cancer Institute, and her colleagues analyzed information from the Surveillance, Epidemiology, and End Results (SEER) program. Their goal was to update the classification of lung cancer subtypes and to determine the rates of lung cancer overall as well as the rates of squamous cell, small cell, adenocarcinoma, large cell, other, and unspecified carcinomas among US whites and blacks diagnosed from 1977 to 2010 and white non-Hispanics, Asian/Pacific Islanders, and white Hispanics diagnosed from 1992 to 2010. The researchers found that squamous and small cell carcinoma rates declined since the 1990s, although less rapidly among females than males…