Tag Archives: harvard

Unsuspected gene found frequently mutated in colorectal, endometrial cancers

Reporting in the October 26, 2014 edition of Nature Genetics, investigators from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard said the mutated gene helps control an important cell-signaling pathway, Wnt, that has been implicated in many forms of cancer. They suggest that the RNF43 mutation may serve as a biomarker that identifies patients with colorectal and endometrial cancer who could benefit from precision cancer drugs that target the Wnt pathway, although no such drugs are currently available. “Tumors that have this mutation may be telling us that they are dependent on the Wnt signaling pathway, and they will be uniquely sensitive to drugs that inhibit this pathway,” said Charles Fuchs, MD, MPH, an author of the paper and director of the Center for Gastrointestinal Cancer at Dana-Farber. He is also affiliated with Brigham and Women’s Hospital and the Harvard School of Public Health…

U.S. has seen widespread adoption of robot-assisted cancer surgery to remove the prostate

In 2001, surgeons began using robotic technologies in operations to remove the prostate. To examine trends in the use of such robotic-assisted radical prostatectomy (RARP) procedures for prostate cancer patients, Steven Chang, MD, MS, of Harvard Medical School, the Dana-Farber Cancer Institute, and Brigham and Women’s Hospital, led a team that analyzed 489,369 men who underwent non-RARP (i.e., open or laparoscopic radical prostatectomy) or RARP in the United States from 2003 to 2010. During the study period, RARP adoption (defined as performing more than 50 percent of annual radical prostatectomies with the robotic approach) increased from 0.7 percent to 42 percent of surgeons performing radical prostatectomies. Surgeons who performed at least 25 radical prostatectomies each year were more likely to adopt RARP…

U.S. has seen widespread adoption of robot-assisted cancer surgery to remove the prostate — ScienceDaily

In 2001, surgeons began using robotic technologies in operations to remove the prostate. To examine trends in the use of such robotic-assisted radical prostatectomy (RARP) procedures for prostate cancer patients, Steven Chang, MD, MS, of Harvard Medical School, the Dana-Farber Cancer Institute, and Brigham and Women’s Hospital, led a team that analyzed 489,369 men who underwent non-RARP (i.e., open or laparoscopic radical prostatectomy) or RARP in the United States from 2003 to 2010. During the study period, RARP adoption (defined as performing more than 50 percent of annual radical prostatectomies with the robotic approach) increased from 0.7 percent to 42 percent of surgeons performing radical prostatectomies. Surgeons who performed at least 25 radical prostatectomies each year were more likely to adopt RARP…