Tag Archives: african

Global health experts call into question sub-Saharan cancer data

Cancer data compiled by the World Health Organisation’s (WHO) GLOBOCAN project has huge global influence and is used by Governments and international NGOs to determine health and funding priorities in sub-Saharan Africa. However, no independent evaluation of the data has ever been undertaken. For the first time, experts from Queen Mary University of London have critically evaluated all publically available information on the quality of cancer registration systems in sub-Saharan Africa. …

Toughest breast cancer may have met its match: Protein inhibitor makes cell susceptible to chemotherapy — ScienceDaily

A report of their findings was published online in the journal Proceedings of the National Academy of Sciences on Dec. 1. Triple-negative breast cancers account for about 20 percent of all breast cancers in the United States, and 30 percent of all breast cancers in African-American women. …

Lactose intolerants at lower risk of certain cancers: Study

“We found that people with lactose intolerance, who typically consume low amounts of milk and other dairy products, have a reduced risk of lung, breast and ovarian cancers,” says Jianguang Ji, Associate Professor at Lund University and researcher at the Center for Primary Care Research in Malm�. “The risk of cancer was not reduced in relatives of people with lactose intolerance, which indicates that protection against these cancers is related to diet. However, it would be wrong to conclude that milk is a risk factor for these cancers,” emphasises Jianguang Ji. There are large differences in the incidence of breast and ovarian cancers between different countries…

New at-risk group identified for gastrointestinal stromal tumors

“Previous journal articles never clearly differentiated GIST from several other tumors, even though they have different biologies,” said Jason Sicklick, MD, assistant professor of surgery and a surgical oncologist at UC San Diego Health System. “This study more clearly identifies at-risk populations in the United States as well as incidence rates, survival trends and risk factors for the disease.” Prior to 2001, GIST-specific histology codes were not used in medical coding, which meant that a variety of tumor types, such as leiomyoma and leiomyosarcoma, spindle cell, myofibroblastic, desmoid and KIT-positive metastatic melanomas were all lumped into one category. Sicklick and his team have used a new generation of precise pathologic diagnostic codes to better define the incidence and distribution of GIST among different patient groups. The research team from UC San Diego Moores Cancer Center found that the overall incidence rate was 6.8 cases per million people and that the rate rose from 2001 to 2011. …

Prostate Cancer: Watchful waiting isn’t right for everyone — ScienceDaily

“We know that African American men have more aggressive prostate cancer than Caucasian men,” says Kosj Yamoah M.D., Ph.D., Chief Resident, Department of Radiation Oncology at Thomas Jefferson University. “Our study shows that African American men who are diagnosed with a low-grade cancer at first — the cancers that are sometimes watched rather than treated — are more likely to develop aggressive disease sooner than Caucasian men.” Dr. Yamoah, together with Timothy Rebbeck and colleagues from the University of Pennsylvania, looked at patients whose cancers were low to intermediate grade and who underwent surgery to remove all or part of their prostate. The surgery was important because often men are given a so called “biopsy” Gleason score of cancer severity based on 12 needle biopsies of the prostate gland…

African American women receive less breast reconstruction after mastectomy

“We wanted to understand whether the racial disparity observed in breast reconstruction among women with breast cancer was related to where women received care, independent of race,” said Tracy Onega, PhD, Associate Professor of Community & Family Medicine, Norris Cotton Cancer Center, and The Dartmouth Institute for Health Policy and Clinical Practice, The Geisel School of Medicine at Dartmouth. “This study fills an important gap in addressing whether racial disparities in breast reconstruction are due — at least in part — to disproportionate use of hospitals with services available.” Breast reconstruction after mastectomy is associated with better quality of life and other benefits — in fact insurance coverage for reconstruction is legislatively mandated. …

Breast cancer specialist reports advance in treatment of triple-negative breast cancer — ScienceDaily

“Impact of the Addition of Carboplatin and/or Bevacizumab to Neoadjuvant Once-Per-Week Paclitaxel Followed by Dose-Dense Doxorubicin and Cyclophosphamide on Pathologic Complete Response Rates in Stage II to III Triple-Negative Breast Cancer: CALGB 40603 (Alliance)” was accepted as a rapid publication and published online this month by the Journal of Clinical Oncology. It will come out in print in September. Because of its rapid growth rate, many women with triple-negative breast cancer receive chemotherapy to try to shrink it before undergoing surgery. With the standard treatment, the cancer is eliminated from the breast and lymph nodes in the armpit before surgery in about one third of women…

Breast cancer specialist reports advance in treatment of triple-negative breast cancer

“Impact of the Addition of Carboplatin and/or Bevacizumab to Neoadjuvant Once-Per-Week Paclitaxel Followed by Dose-Dense Doxorubicin and Cyclophosphamide on Pathologic Complete Response Rates in Stage II to III Triple-Negative Breast Cancer: CALGB 40603 (Alliance)” was accepted as a rapid publication and published online this month by the Journal of Clinical Oncology. It will come out in print in September. Because of its rapid growth rate, many women with triple-negative breast cancer receive chemotherapy to try to shrink it before undergoing surgery. …