Tag Archive psa

Vaccine therapy for prostate cancer patients with rising PSA examined — ScienceDaily

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As part of a Phase II clinical trial, adult patients with advanced prostate cancer (as evidenced by two rising prostate-specific antigen or PSA values and no visible metastasis) whose cancer is resistant to hormone therapy and had either surgery or radiation were recruited from member institutions in the ECOG-ACRIN Cancer Research Group. In their work, published in the current online edition of European Urology, ECOG-ACRIN investigators examined two different experimental treatment options. In step one, patients were treated with PROSTVAC-V/TRICOM and PROSTVAC-F/TRICOM. PROSTVAC-V is derived from a vaccinia virus that was used for many years to vaccinate against smallpox. …

Vaccine therapy for prostate cancer patients with rising PSA examined

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As part of a Phase II clinical trial, adult patients with advanced prostate cancer (as evidenced by two rising prostate-specific antigen or PSA values and no visible metastasis) whose cancer is resistant to hormone therapy and had either surgery or radiation were recruited from member institutions in the ECOG-ACRIN Cancer Research Group. …

New prostate cancer screening guideline recommends not using PSA test — ScienceDaily

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“Some people believe men should be screened for prostate cancer with the PSA test but the evidence indicates otherwise,” states Dr. Neil Bell, member of the Canadian Task Force on Preventive Health Care and chair of the prostate cancer guideline working group. “These recommendations balance the possible benefits of PSA screening with the potential harms of false positives, overdiagnosis and treatment of prostate cancer.” For men with prostate cancer diagnosed through PSA screening, between 11.3% and 19.8% will receive a false-positive diagnosis, and 40% to 56% will be affected by overdiagnosis leading to invasive treatment…

Professional recommendations against routine prostate cancer screening have little effect — ScienceDaily

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The study, published as a research letter online in JAMA Internal Medicine, focused on the use of PSA — prostate-specific antigen — to test for prostate cancer. “We found that the effect of the guidelines recommending against the routine screening of elderly men in particular has been minimal at best,” says Jesse Sammon, D.O., a researcher at Henry Ford’s Vattikuti Urology Institute and lead author of the study. The researchers found an estimated 17 million men age 50 or older without a history of prostate cancer or prostate problems who reported undergoing PSA screening…

Blood test for ‘nicked’ protein predicts prostate cancer treatment response

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The study evaluated two groups of 31 men with prostate cancer that had spread and whose blood levels of prostate-specific antigen (PSA) were still rising despite low testosterone levels. Investigators gave each man either enzalutamide (Xtandi) or abiraterone (Zytiga) and tracked whether their PSA levels continued to rise, an indication that the drugs were not working. In the enzalutamide group, none of 12 patients whose blood samples tested positive for AR-V7 responded to the drug, compared with 10 responders among 19 men who had no AR-V7 detected. In the abiraterone group, none of six AR-V7-positive patients responded, compared with 17 responders among 25 patients lacking AR-V7. …

New method for non-invasive prostate cancer screening

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Now a team of researchers led by Shaoxin Li at Guangdong Medical College in China has demonstrated the potential of a new, non-invasive method to screen for prostate cancer, a common type of cancer in men worldwide. …

Recommendations for prostate cancer active surveillance — ScienceDaily

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With active surveillance, patients undergo regular visits with prostate-specific antigen (PSA) tests and repeated prostate biopsies rather than aggressive treatment. …

Prostate cancer screening reduces deaths by a fifth: Large, long-term European trial — ScienceDaily

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Despite this new evidence for the effectiveness of prostate-specific antigen (PSA) testing to reduce mortality, doubts as to whether the benefits of screening outweigh the harms remain, and routine PSA screening programmes should not be introduced at this time, conclude the authors. The European Randomised study of Screening for Prostate Cancer (ERSPC) began in 1993 to determine whether screening men for PSA reduces deaths from prostate cancer. …

Vasectomy may increase risk of aggressive prostate cancer — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/07/140709182240.htm

Image fusion-guided biopsy significantly improves accuracy of prostate cancer diagnosis — ScienceDaily

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source : http://www.sciencedaily.com/releases/2014/05/140521133838.htm