Tag Archives: spotlight

Long term study: Breast cancer risk increased in young women after treatment for Hodgkin’s disease

The incidence figures for secondary breast cancer are based on long-term observation of 590 female patients in the German-Austrian pediatric treatment trials dating back to the years 1978 to 1995. The authors estimate that 19% of the girls treated with radiotherapy for Hodgkin’s disease develop secondary breast cancer within 30 years as a result of that therapy. …

Methylation signaling controls cancer growth

Angiogenesis creates new blood vessels in a process that can lead to the onset and progression of several diseases such as cancer and age-related macular degeneration. Vascular endothelial growth factor (VEGF) is a signaling protein produced by damaged cells, which binds to one of its receptors VEGFR-2, located on the surface of blood vessel cells. …

Scientists find potential new clues for identifying breast cancer risk

Dr. David Gilley’s laboratory at the Indiana University School of Medicine in Indianapolis and Dr. Connie Eaves’ laboratory at the BC Cancer Agency’s Terry Fox Laboratory in Vancouver, Canada, collaborated to determine how telomeres are regulated in different types of normal breast cells. …

‘Junk DNA’ plays active role in cancer progression, researchers find

The researchers, led by Dr Cristina Tufarelli, in the School of Graduate Entry Medicine and Health Sciences, discovered that the presence of this faulty genetic element — known as chimeric transcript LCT13 — is associated with the switching off of a known tumour suppressor gene (known as TFPI-2) whose expression is required to prevent cancer invasion and metastasis. …

When it comes to cancer, information is power

Noreen asked me to fill in for her today.  Don't worry, she has actually been feeling better this past week.  She got to take a break from chemo, which always makes her feel better, and she learned her tumor markers dropped from 600 to 53!  We are very excited about that bit of news. The reason I am writing this week is because there has been a lot of attention given to the announcement by Angelina Jolie that she underwent a preventative double mastectomy with reconstruction when she learned she had the BRCA (BReast CAncer ) gene.   I, too, had the surgery after testing positive for the gene.  People, myself included, were stunned by Angelina's announcement.  When one of the most famous and arguably beautiful women in the world has a preventative mastectomy, it sheds a spotlight on the issue and reminds us that not even fame and fortune can save us from cancer.   Since Angelina “came out,” breast cancer advocates, doctors, news commentators and others have given their opinions on whether or not Angelina and other women with the breast cancer gene and/or breast cancer have made the “right” decision by having a double mastectomy. But there is no “right” or “wrong” in these situations.  No one wants a mastectomy . . . no one.  Women (and some men) choose the long, painful and disfiguring surgery to either remove cancer from their bodies or to try and prevent it when they have a greatly increased risk of getting breast cancer.    Angelina and I had an 87 percent chance of developing breast cancer.  Eighty-seven percent! You have all followed Noreen's blogs.  She is one of my closest friends.  When I compared having a mastectomy to what she has endured, for me, a mastectomy felt like the better option.   Still, the message I want to send is that surgery is not the only option for women who have the breast cancer gene or otherwise have an increased risk. The important thing is that you don't keep your head in the sand.  Information is power.  You should talk to your health care provider and determine whether you are at an increased risk.   If testing for the breast cancer gene is recommended, just remember your life won't change if you find out you have it; you just have more information so you can explore more options.   Surgery is just one option.  Women at high risk are also eligible for increased screenings, which could help “catch” cancer early and give you a fighting chance if you do develop the disease.   Like I said, there is no right or wrong answer, but when you have all of the information, you can determine what option is best for you.     Noreen will be back next week.  Until then, keep up with her on Facebook    Michelle McBride is the President of the Noreen Fraser Foundation.source : http://www.foxnews.com/health/2013/05/15/when-it-comes-to-cancer-information-is-power/

Review on aspirin to treat and prevent heart attacks and commentary on aspirin to prevent colorectal and other cancers

This update was published in the current issue of the American Journal of Medicine by Hennekens and James E. Dalen, M.D., M.P.H., dean emeritus, University of Arizona College of Medicine and executive director of the Weil Foundation. In a commentary published in Clinical Investigation, Hennekens and David J…