“The take-home message of the study is that we have found a way to target breast cancer metastasis through a pathway regulated by an enzyme,” said lead author Xuefeng Wu, PhD, a postdoctoral researcher at UC San Diego. The enzyme, called UBC13, was found to be present in breast cancer cells at two to three times the levels of normal healthy cells. …
Now a team of scientists, led by Prof. Taeghwan Hyeon at the Institute for Basic Science (IBS)/Seoul National University and Prof. …
Acute lymphoblastic leukemia (ALL) is the most common cancer of childhood. This disease hinders the development of healthy blood cells while cancer cells proliferate. Currently, children with ALL receive chemotherapy for two to three years, exposing them to significant side effects including changes in normal development and future fertility. As a way to avoid these adverse effects, investigators have been researching how to supercharge the body’s innate cancer-fighting ability — a technique called immunotherapy…
Acute lymphoblastic leukemia (ALL) is the most common cancer of childhood. This disease hinders the development of healthy blood cells while cancer cells proliferate. Currently, children with ALL receive chemotherapy for two to three years, exposing them to significant side effects including changes in normal development and future fertility. …
Researchers at Boston University School of Medicine (BUSM) conducted hundreds of interviews to offer new insights into this frequent — and often controversial — clinic room conversation. …
Reporting online recently in the journal Gut, researchers at Washington University School of Medicine in St. Louis said they have made cell lines from individual patients in as little as two weeks…
GRP78, a protein that protects cells from dying, is more abundant in cancer cells and tissue than in normal organs and is thought to play a role in helping pancreatic cancer cells survive and thrive. Researchers at the University of Minnesota have found triptolide, an extract of the Chinese herb thunder god vine (Tirpterygium wilforii), suppresses GRP78, eventually leading to pancreatic cancer cell death. For mammals to use the proteins in our bodies, a process called protein folding must occur in the endoplasmic reticulum (ER) of cells. If proteins are not folded fast enough, unfolded proteins begin to build up and the cell becomes stressed…
Researchers at the Centre for Primary Health Care Research at Lund University and Region Skåne in Sweden have presented the new research findings based on studies of population registers. “The results of our study do not mean that an individual’s lifestyle is not important for the individual’s risk of developing cancer, but it suggests that the risk for the three most common types of cancer is dependent to a greater extent on genetics,” said Bengt Zöller, a reader at Lund University who led the study. The researchers studied adoptees born in Sweden in relation to both their biological parents and their adoptive parents. The Swedish multi-generation register and the cancer register were used to monitor 70 965 adopted men and women. …
The study, published today in Annals of Family Medicine, tracked screening rates for cervical, breast and colorectal cancer in Ontario each year between 2000 and 2010. Researchers found no significant changes in breast and cervical cancer screening rates after bonuses were introduced for doctors in 2006. …
source : http://www.sciencedaily.com/releases/2014/07/140722102249.htm