Tag Archives: national

Genetic signature of deadly brain cancer identified

"This study identifies a core set of genes and pathways that are dysregulated during both the early and late stages of tumor progression," said University of Rochester Medical Center (URMC) neurologist Steven Goldman, M.D., Ph.D., the senior author of the study and co-director of the Center for Translational Neuromedicine. "By virtue of their marked difference from normal cells, these genes appear to comprise a promising set of targets for therapeutic intervention." As its name implies, gliomas arise from a cell type found in the central nervous system called the glial cell. Gliomas progress in severity over time and ultimately become highly invasive tumors known as glioblastomas, which are difficult to treat and almost invariably fatal. …

Mystery behind dormant breast tumor cells that become metastatic unlocked

In a small but significant number of breast cancer patients, cancerous cells can move through the bloodstream from breast tissue to secondary sites in other parts of the body where they may remain in a dormant state, clinically undetected, for an extended period of time, before suddenly becoming metastatic. …

Michael Douglas’ interview: Can you get throat cancer from oral sex?

The Guardian newspaper published an interview with Michael Douglas on Sunday, in which the 68-year-old actor said his throat cancer hadn’t been caused by drinking or smoking – but by having oral sex. “Without wanting to get too specific, this particular cancer is caused by HPV, which actually comes about from cunnilingus,” Douglas told the British newspaper.  Douglas also went on to speculate that the stress of his son Cameron’s incarceration might have helped trigger the cancer as well. While a representative for Douglas maintains the actor did not specifically say oral sex was the cause of his cancer, the conversation still begs the question: Does having oral sex play a role in the development of oral cancer? While a connection between the two may seem bizarre, it is very possible that some oral cancers are the end result of intimate sexual contact. Rates of oral cancer – sometimes referred to as head and neck cancers – have been on the rise over the past decade.  While the main risk factors for oral cancers typically include drinking alcohol and smoking, around 25 percent of mouth and 35 percent of throat cancers are related to human papilloma virus (HPV) infection. “(HPV) is present within the fluids that are part of oral sexual behavior,” Dr. Marshall Posner, director of the head and neck oncology program at Mount Sinai Hospital in New York City, told FoxNews.com. “The vaginal fluids and semen will contain epithelial cells that have the virus on them and also free viral particles that can cause infection.” HPV cannot be transmitted through blood contact, but Posner said it may be possible to contract the virus from the direct contact of fluids through kissing. This can occur if an individual kisses someone who previously performed oral sex on someone else who had the virus. “If the virus is present in the oral pharynx and if it gets secreted in the saliva, then the saliva will contain potentially dangerous viral particles,” Posner said. There are more than 100 different types of HPV, and nearly everyone contracts some form of the virus in their youth.  Fortunately, the majority of HPV strains do not cause any symptoms, and in 90 percent of cases, the infection is naturally eradicated from the body within two years. However, some HPV types can cause genital warts, while others may lead to certain cancers in rare cases. HPV 16 and HPV 18 – which are sexually transmitted – are most closely associated with HPV-positive oropharyngeal cancer. According to Posner, 3 percent of adult males and 1 percent of adult females will have detectable HPV 16 in their saliva at any given moment in time.  However, just because HPV is detected in a sample of someone with oral cancer does not necessarily mean HPV caused the cancer.  According to the National Health Service in Britain, the virus becomes part of the pre-existing cancer cells’ genetic material, fostering the cells to grow. Oropharyngeal cancer symptoms include a lump in the back of the throat or mouth, pain in the ear or back of tongue, and difficulty swallowing. While the prognosis for HPV-negative oropharyngeal cancer is around 40 to 50 percent, the survival outcomes are generally better for HPV-positive cancers, ranging from 80 to 95 percent.  However, that prognosis is affected by drinking and smoking, which may have been a problem for Douglas. In the United States, HPV-related oropharyngeal cancer represents 60 percent of the total number of orapharyngeal cancer cases, which equal to about 15,000 per year.  Posner estimated that those cases will increase to 20,000 a year by the year 2015. While researchers cannot fully explain the rising rates of these cancers, one of the biggest risk factor for contracting HPV-positive oroharyngeal cancer includes having a high number of sexual partners, Posner said. “In smoking cigarettes and cancer, it doesn’t matter what brands you smoked, it matters how many you smoked,” Posner said.  “With HPV, it’s about the number of ‘brands’ you’ve been involved with. If you have numerous partners, you have a much higher risk of developing cancer. So (monogamous) people should go ahead and have the same intimate and personal relationship that they have with their partners and not be worried about it.” For those looking to protect themselves from contracting dangerous forms of HPV, practicing safe sex by using protection such as condoms and dental dams may help to diminish the spread of sexually transmitted diseases.  Posner also called for parents to get their children – including young boys –vaccinated against HPV. “I think people should make every effort to have children vaccinated, so I don’t have to treat this in the future,” Posner said.  I think it’s very important and to cure cancer we have to support research – it’s the best way we have to figure out how to cure this. Click to learn more about HPV from Mount Sinai Hospital.source : http://www.foxnews.com/health/2013/06/03/michael-douglass-reveal-can-get-throat-cancer-from-oral-sex/

Michael Douglas’ reveal: Can you get throat cancer from oral sex?

Michael Douglas made a shocking announcement on Sunday, maintaining that his throat cancer hadn’t been caused by drinking or smoking – but by having oral sex. “Without wanting to get too specific, this particular cancer is caused by HPV, which actually comes about from cunnilingus,” Douglas told The Guardian newspaper.  The 68-year-old actor also went on to speculate that the stress of his son Cameron’s incarceration might have helped trigger the cancer as well. While a connection between oral sex and cancer may seem bizarre, it is very possible that some oral cancers are the end result of intimate sexual contact. Rates of oral cancer – sometimes referred to as head and neck cancers – have been on the rise over the past decade.  While the main risk factors for oral cancers typically include drinking alcohol and smoking, around 25 percent of mouth and 35 percent of throat cancers are related to human papilloma virus (HPV) infection. “(HPV) is present within the fluids that are part of oral sexual behavior,” Dr. Marshall Posner, director of the head and neck oncology program at Mount Sinai Hospital in New York City, told FoxNews.com. “The vaginal fluids and semen will contain epithelial cells that have the virus on them and also free viral particles that can cause infection.” HPV cannot be transmitted through blood contact, but Posner said it may be possible to contract the virus from the direct contact of fluids through kissing. This can occur if an individual kisses someone who previously performed oral sex on someone else who had the virus. “If the virus is present in the oral pharynx and if it gets secreted in the saliva, then the saliva will contain potentially dangerous viral particles,” Posner said. There are more than 100 different types of HPV, and nearly everyone contracts some form of the virus in their youth.  Fortunately, the majority of HPV strains do not cause any symptoms, and in 90 percent of cases, the infection is naturally eradicated from the body within two years. However, some HPV types can cause genital warts, while others may lead to certain cancers in rare cases. HPV 16 and HPV 18 – which are sexually transmitted – are most closely associated with HPV-positive oropharyngeal cancer. According to Posner, 3 percent of adult males and 1 percent of adult females will have detectable HPV 16 in their saliva at any given moment in time.  However, just because HPV is detected in a sample of someone with oral cancer does not necessarily mean HPV caused the cancer.  According to the National Health Service in Britain, the virus becomes part of the pre-existing cancer cells’ genetic material, fostering the cells to grow. Oropharyngeal cancer symptoms include a lump in the back of the throat or mouth, pain in the ear or back of tongue, and difficulty swallowing. While the prognosis for HPV-negative oropharyngeal cancer is around 40 to 50 percent, the survival outcomes are generally better for HPV-positive cancers, ranging from 80 to 95 percent.  However, that prognosis is affected by drinking and smoking, which may have been a problem for Douglas. In the United States, HPV-related oropharyngeal cancer represents 60 percent of the total number of orapharyngeal cancer cases, which equal to about 15,000 per year.  Posner estimated that those cases will increase to 20,000 a year by the year 2015. While researchers cannot fully explain the rising rates of these cancers, one of the biggest risk factor for contracting HPV-positive oroharyngeal cancer includes having a high number of sexual partners, Posner said. “In smoking cigarettes and cancer, it doesn’t matter what brands you smoked, it matters how many you smoked,” Posner said.  “With HPV, it’s about the number of ‘brands’ you’ve been involved with. If you have numerous partners, you have a much higher risk of developing cancer. So (monogamous) people should go ahead and have the same intimate and personal relationship that they have with their partners and not be worried about it.” For those looking to protect themselves from contracting dangerous forms of HPV, practicing safe sex by using protection such as condoms and dental dams may help to diminish the spread of sexually transmitted diseases.  Posner also called for parents to get their children – including young boys –vaccinated against HPV. “I think people should make every effort to have children vaccinated, so I don’t have to treat this in the future,” Posner said.  I think it’s very important and to cure cancer we have to support research – it’s the best way we have to figure out how to cure this. Click to learn more about HPV from Mount Sinai Hospital.source : http://www.foxnews.com/health/2013/06/03/michael-douglass-reveal-can-get-throat-cancer-from-oral-sex/

Gene flaws surprisingly common in black women with breast cancer

Gene flaws that raise the risk of breast cancer are surprisingly common in black women with the disease, according to the first comprehensive testing in this racial group. The study found that one-fifth of these women have BRCA mutations, a problem usually associated with women of Eastern European Jewish descent but recently highlighted by the plight of Angelina Jolie. The study may help explain why black women have higher rates of breast cancer at young ages - and a worse chance of survival. Doctors say these patients should be offered genetic counseling and may want to consider more frequent screening and prevention options, which can range from hormone-blocking pills to breast removal, as Jolie chose to do. “We were surprised at our results,” said the study leader, Dr. Jane Churpek, a cancer specialist at the University of Chicago. Too few black women have been included in genetic studies in the past and most have not looked for mutations to the degree this one did, “so we just don't have a good sense” of how much risk there is, she said. Churpek gave results of the study Monday at an American Society of Clinical Oncology conference in Chicago. The researchers include Mary-Claire King, the University of Washington scientist who discovered the first breast cancer predisposition gene, BRCA1. Jolie revealed a few weeks ago that she carries a defective BRCA1 gene, giving her up to an 87 percent risk of developing breast cancer and up to a 54 percent risk for ovarian cancer. The actress's mother had breast cancer and died of ovarian cancer, and her maternal grandmother also had ovarian cancer. An aunt recently died of breast cancer. Children of someone with a BRCA mutation have a 50 percent chance of inheriting it. In the U.S., about 5 to 10 percent of breast cancers are thought to be due to bad BRCA genes. Among breast cancer patients, BRCA mutations are carried by 5 percent of whites and 12 percent of Eastern European (Ashkenazi) Jews. The rates in other groups are not as well known. The study involved 249 black breast cancer patients from Chicago area hospitals. Many had breast cancer at a young age, and half had a family history of the disease. They were given complete gene sequencing for all 18 known breast cancer risk genes rather than the usual tests that just look for a few specific mutations in BRCA genes. Gene flaws were found in 56, or 22 percent, of study participants; 46 of them involved BRCA1 or BRCA2 and the rest were less commonly mutated genes. Harmful mutations were found in 30 percent of black women with “triple-negative breast cancer” - tumors whose growth is not fueled by estrogen, progesterone or the gene that the drug Herceptin targets. Doctors have long known that these harder-to-treat cases are more common in black women. The National Cancer Institute, the Breast Cancer Research Foundation and Komen for the Cure paid for the study. It included many younger women and those with a family history of cancer, and they are known to have higher rates of gene mutations that raise risk, said Rebecca Nagy, a genetics counselor at Ohio State University and president of the National Society of Genetic Counselors. Still, “it has always stumped us” to see black families with lots of breast cancer but no mutations that can be found in ordinary testing for BRCA genes, she said. That was the situation for Alicia Cook, 44, a Chicago woman whose grandmother died of breast cancer, mother died of ovarian cancer and two sisters have had breast cancer. When she was first diagnosed with breast cancer nearly 10 years ago, a test for BRCA mutations was negative. Doctors said, “I'm sure there's something going on genetically” but they didn't have the tools to find it, Cook said. Last year, she had a recurrence and a sister who was diagnosed with the disease learned she carried a BRCA1 mutation. Cook was retested for the same mutation and found to have it. Now she is telling her relatives in hopes that more of them will seek genetic counseling and be aware of their risk. “You don't want to put people in fear, but knowledge is power,” she said.source : http://www.foxnews.com/health/2013/06/03/gene-flaws-common-in-black-women-with-breast-cancer/

Could shedding extra pounds improve psoriasis?

Losing weight may ease psoriasis and improve quality of life for some overweight people with the chronic skin disease, new research from Denmark suggests. But the trial may have been too small to fully flesh out that link, and researchers said future studies will have to follow larger groups of patients for more time to make definitive conclusions. “The results, I would say, are promising,” said Dr. Joel Gelfand, a dermatologist from the University of Pennsylvania Perelman School of Medicine in Philadelphia. “It's still excellent advice to patients who are overweight with psoriasis to lose weight.” According to the National Institutes of Health, more than three percent of U.S. adults have psoriasis, which is characterized by itchy, painful plaques on the skin. Over the years, researchers have learned that obese people are more likely to develop psoriasis than their thinner peers and tend to have more severe disease. That could be due to more body-wide inflammation among people carrying around extra fat. “It's more than one thing that causes it, but obesity is probably one of the factors that can bring on psoriasis,” Gelfand, who wasn't involved in the new study, told Reuters Health. Genetics also plays a role. Conversely, Gelfand said there's been some suggestion that losing weight may ease psoriasis symptoms, based on reports of people who had bariatric surgery and saw their skin condition improve. For the new study, researchers led by Dr. Peter Jensen from Copenhagen University Hospital Gentofte wanted to shed more light on how weight loss influences psoriasis. They randomly assigned 30 overweight and obese people with psoriasis to go on a 4-month weight-loss diet of 800 to 1,200 calories per day and another 30 to stick to typical nutrition guidelines. By the end of the study, participants in the diet group had lost an average of 35 pounds, on average, compared to just one pound in the non-diet group. Dieters had a borderline larger improvement in their psoriasis severity and the amount of their body covered by psoriasis plaques. They started the study with an average severity score of 4.8, on a scale of 0 to 72. By 4 months, that had fallen to 2.5. Non-dieters saw only a slight drop in their psoriasis cover and severity, from 5.5 to 5.2. People in the weight-loss group also reported greater improvements in their quality of life during the study period, Jensen and his colleagues wrote Wednesday in JAMA Dermatology. The diet was tied to some mild side effects, including headaches and dizziness. One patient complained of being hungry throughout the study, the researchers reported, and another “consumed large amounts of sugar-free licorice, resulting in hypokalemia (low potassium) that normalized after he was instructed to stop eating licorice.” Gelfand said that because patients started out with mild to moderate psoriasis, they didn't have much room to improve when they lost weight. That, combined with the small group size, limits some of the conclusions that can be taken from the study. “The next step would be to do a much larger study in patients who have more severe psoriasis,” Gelfand said. In the meantime, he said weight loss can have other benefits for heavy people with psoriasis, such as improving how they respond to some medications and lowering their risk of heart disease.source : http://www.foxnews.com/health/2013/05/31/could-shedding-extra-pounds-improve-psoriasis/

Pork industry hunts for deadly pig virus

The sudden and widespread appearance of a swine virus deadly to young pigs - one never before seen in North America - is raising questions about the bio-security shield designed to protect the U.S. food supply. The swine-only virus, the Porcine Epidemic Diarrhea Virus (PEDV), poses no danger to humans or other animals, and the meat from infected pigs is safe for people to eat. Though previously seen in parts of Asia and Europe, the virus now has spread into five leading hog-raising U.S. states. How it arrived in the United States remains a mystery. While the U.S. imports millions of pigs each year from Canada, it imports pigs from virtually no other country, and no Canadian cases of PEDV have been confirmed. Veterinarians and epidemiologists say pigs are infected through oral means, and that the virus is not airborne and does it not occur spontaneously in nature. In recent years, with the emergence of dangerous pathogens such as H1N1, also known as swine flu, and bovine spongiform encephalopathy (BSE) or mad cow disease, the United States and other countries have sought to secure defenses both on the farm and at the national borders to protect against barnyard epidemics. “We're just trying to get a handle on what's happening,” said Tom Burkgren, executive director of the American Association of Swine Veterinarians. “It's like drinking water out of a fire hose. We're getting hits from all over the place.” Overall numbers of confirmed cases and mortality rates are not yet available, though anecdotal evidence suggests there are devastating losses for farms that are hit. “If you've got it, it's bad,” said Mark Greenwood, vice president of agri-business capital at AgStar Financial Services, who said none of his clients have been affected. “I spoke to a farmer in the Midwest who had it show up in a 2,000-head barn of pigs, and had a 40 percent death loss.” A spokeswoman for U.S. Department of Agriculture's Animal and Plant Health Inspection Service told Reuters the agency is working with state agencies and pork industry officials to discover where the virus originated. THE VIRUS SPREADS Confirmed cases have been reported in five hog-raising states including Iowa, the largest U.S. hog producer with 20 million hogs, according to the USDA. While only seven farms have had confirmed cases since May 17, more cases are expected as labs sift through samples, say sources investigating the outbreak. Colorado, Indiana, Illinois and Minnesota reportedly have positive tests for PEDV, according to state veterinarians and agriculture department officials, and the National Veterinary Services Laboratory in Ames, Iowa. PEDV, most often fatal to very young pigs, causes diarrhea, vomiting and dehydration. It also sickens older hogs, though their survival rate tends to be high. Known as a “coronavirus” because of the crown-like spikes on its surface, the virus afflicted China in recent years and killed more than 1 million piglets. PEDV is spread most commonly by pigs ingesting contaminated feces. Investigators are focused on physical transmission, perhaps a PEDV infected pig, equipment marred with feces, or even a person wearing dirty boots or with dirty nails. The mystery about how the virus entered the United States is raising concern about potential holes in the bio-security shield designed to protect the U.S. food and farming sectors. “Like everything else, we screw up from time to time,” said Ronald L. Plain, professor of agricultural economics at University of Missouri in Columbia, Missouri. “We know so little about the transmittal of this virus. We can't be sure if it's happening because of something we're supposed to do right and didn't - or by some mechanism we don't know that we're supposed to do differently.” Initial reporting about the virus may have been delayed, say sources, because its symptoms can be confused with a more common malady, transmissible gastroenteritis (TGE). Also, states are not required to report cases of PEDV to the federal government, and farmers are not required to report to state veterinarians. As part of its assessment of the situation, USDA will email epidemiological surveys to swine veterinarians who are dealing cases of PEDV. Meanwhile, the veterinarians are sending samples to diagnostic labs, where technicians are scrambling gathering the tools needed to check the samples for PEDV - supplies many labs did not have prior to the outbreak. While most farmers are taking a wait-and-see approach, some told Reuters they are turning away unnecessary visitors and double checking to ensure their safety protocols are being followed. LOOKING NORTH The search for leads also has turned to the nation's borders and ports of entry - specifically, Canada, where the United States imported 5.7 million head of live hogs last year. Canada has never had a confirmed case of the virus, though it does not test for it, government officials said. “Canada has very effective import measures in place to address this risk,” said Dr. Rajiv Arora, senior staff veterinarian for the Canadian Food Inspection Agency's foreign animal disease section. Canada can import live breeding pigs, under permits, from either the United States or the European Union, Arora said. The animals are quarantined by CFIA for a period of time, then inspected and tested - although not for PEDV - before released. Canada imported C$1.7 million ($1.6 million) worth of live swine in 2012, including both slaughter-ready and breeder pigs, according to Canada's Agriculture Department. CHINA HARD HIT Veterinarians and agricultural epidemiologists in the United States are drawing grim lessons from the devastating effect PEDV has had in other countries where it has hit. The first reports of suspected PEDV came in 1971 in the United Kingdom. As years passed, PEDV spread across parts of Europe and Asia. Veterinary researchers later concluded that lax bio-security measures contributed to PEDV's spread in Asia. One of the worst known outbreaks of the virus hit China's pig herds in late 2010, according to the Centers for Disease Control and Prevention's Emerging Infectious Diseases Journal. Vaccines had limited effectiveness and PEDV over ran southern China killing more than 1 million piglets. The death rate for virus-infected piglets ranged from 80 percent to 100 percent. Biosecurity measures in the U.S. food supply have been beefed up over the years, and especially after the outbreaks of mad cow disease and swine flu. Both outbreaks posed risks to human health. Today, trucks carrying live animals are supposed to be cleaned before entering and leaving farms. At commercial hog operations, visitors routinely shower and change clothing before stepping into a barn. Overseas visitors typically wait several days before being in the presence of a commercially raised hog. But the food shield is not impermeable. “If it becomes clear that this is not a novel way for to be transmitted, and that there had to be physical contact, that's going to be a major concern,” said William Marler, a leading food-safety attorney. “It means that there was a failure in the system.”source : http://www.foxnews.com/health/2013/05/29/pork-industry-hunts-for-deadly-pig-virus/

GATA-3 is important for regulation and maintenance of immune system

GATA-3’s role in CD4 T-cells has been widely studied, but its role in CD8+ cells has received much less attention. "We want to know what the basic function of GATA-3 in regulating cell biology is, although it has been shown that GATA-3 is important for the function of CD4+ T cell type to clear extracellular parasites," said Yisong Wan, PhD, assistant professor of microbiology and immunology at the UNC School of Medicine and member of UNC Lineberger Comprehensive Cancer Center. The research, published online May 26 by Nature Immunology, shows that GATA-3 is required for the maintenance and function of CD8+ T-cells, a T-cell type mediating the immune response to clear pathogens, eradicate tumors and promote inflammation. …

Dealing with mean girls — and boys — in the workplace

Though most mean girls and tough boys of middle and high school grow out of their sophomoric behaviors, some cling to them well beyond college and into adulthood. That means you may encounter this behavior in the workplace. Author Meredith Fuller, a psychologist in Australia, interviewed over 200 women about mean girls in the workplace for her book, Working with Bitches. She discovered that certain personality “types” can make the lives of their coworkers miserable just as they did back in school. Grown women may feel some of the similar inhibitions they felt as teenagers when dealing with these difficult personalities in the workplace. Here are some of the most difficult personality types and how to deal with them: The Excluder:  She barely acknowledges you, pretends you don’t exist, fails to include you in important meetings and doesn’t bother giving you important information. How to cope: Most women don’t like to be disliked or excluded from the group, but ask yourself if you really want to be this person’s friend anyway. There’s a good chance you don’t. Her cold shoulder may simply be pushing a button of an earlier school girl experience. But if you flip your perspective and don’t take it personally, you may enjoy not having the burden of having to interact with her. This could be tricky, though, if you need information or input from her, but removing your emotional response will definitely ease these interactions. “Work out alternative ways to gather data or whatever else you need to do your job properly,” writes Fuller. Don’t try to push or goad her into communicating with you. You’ll just get the same treatment in spades. Instead, be civil and respond in a measured, mature way. That will help to diminish her effect on you.   The Screamer:  He yells to intimidate, insult and get a reaction. Like Ari Gold of Entourage, he's tightly wound and barks instructions at full volume. He’s critical and thinks he’s the only one who can get the job done correctly. He wants you to drop everything and race after whatever he's demanding. He’s volatile, impulsive and throws insults around the office. How to cope:  A screamer can’t hear you when he’s in a rage. So wait until he’s done before attempting to respond to his accusations. He probably doesn’t even want a response, because screaming is a one-way conversation. Trying to argue will only escalate it. Once you’ve identified a screamer, you can brace yourself to some degree for his outbursts – though they may still take a toll on you. Look at your own response to screamers, which is often influenced by your own experiences growing up. Do you find it highly distressing? Do you find it amusing, like watching a child have a tantrum? Or can you keep an emotional distance

Money talks when it comes to weight loss

The secret to weight loss may be much simpler than anyone ever imagined – so simple, in fact, you may wonder why it hasn’t been thought of before? A study completed by Mayo Clinic researchers has discovered that money is the most effective motivator when it comes to weight loss. When conducting a comparison between study groups, one group was incentivized, the other was not. The results were overwhelming, with 62 percent of study participants from the incentivized group completing the study, compared to only 26 of the non-incentivized group. And, the incentivized group lost an average of 9.08 pounds versus 2.34 pounds in the other group. Financial incentives for weight loss began to gain popularity in January, as New Year’s resolutions to finally drop excess pounds began to dominate water cooler chatter in offices across the nation. A number of websites and wellness firms now offer individuals, as well as teams, the ability to place bets on their weight loss efforts, and some even offer additional tools to help you succeed. According to a report by the National Business Group on Health, teaming up with co-workers to whittle your middle is an effective way to lose weight.  The media lit up in the wake of New Year’s resolutions to discuss the increases in employer-incentivized weight loss competitions. Wellness consultant groups and websites, like DietBet.com and Healthywage.com, have helped tens of thousands of employees shed as much as 5 percent of their body weight in just three months – enough to make a significant  difference in certain health risk factors. The effectiveness of the program is in line with the Mayo Clinic study: money talks when it comes to weight loss. And inside the office, the team mentality only enhances success. Independent wellness firms work with employers to establish teams within the office and offer a grand prize (as much as $10,000 cash) for the winning team and smaller prizes for milestones along the way, as well as runner-up rewards. In an interview, an employee of a participating company told The Wall Street Journal that staying on track was easier because he feared letting down his team in the pursuit of $10,000. A fellow teammate responded, agreeing, “The last thing you want to do is catch the wrath of your team.” Independent firms offer complete programs, including private weigh-ins. Employees may participate on a voluntary basis and a small fee is often required, but the rewards – even if you don’t win the grand prize – often outweigh the fee. There is speculation, as with most diets, about maintaining your weight loss after the allure of the money has long passed. However, studies have shown that in team weight loss “competitions” like these, many times teammates continue to help each other stay on track. Physician-supervised weight loss is also a healthy way to not only achieve weight loss results for contests like these, but to ensure you maintain it. Your doctor can be a vital part of your weight management team and help you uncover strategies that will lead to long term weight loss success – long after you have pocketed your weight loss earnings. Click to learn more about the Mayo Clinic study. Dr. Jennifer Landa is Chief Medical Officer of BodyLogicMD, the nation's largest franchise of physicians specializing in bioidentical hormone therapy. Dr. Jen spent 10 years as a traditional OB-GYN, and then became board-certified in regenerative medicine, with an emphasis on bio-identical hormones, preventative medicine and nutrition. She is the author of “The Sex Drive Solution for Women.” & Learn more about her programs at www.jenlandamd.com.& source : http://www.foxnews.com/health/2013/05/27/money-talks-when-it-comes-to-weight-loss/