The researchers published their findings, "Silencing of RB1 and RB2/p130 during adipogenesis of bone marrow stromal cells results in dysregulated differentiation," in the Feb. 1, 2014, issue (online Nov. 25) of the journal Cell Cycle…
Clinical Cancer Advances 2013: ASCO’s Annual Report on Progress Against Cancer reveals how marked expansion in our knowledge and understanding of cancer is already improving treatment while also pointing the way towards even more effective approaches in the future. Published today in the Journal of Clinical Oncology, the ASCO report covers a broad range of cancer types and highlights a selection of the most recent achievements across the entire continuum of cancer care, from prevention and screening to treatment and survivorship. "For patients today, these results can be critical. Scientifically, they demonstrate how our long term investment in science and technology can yield practical advances now and in the near future," said ASCO President Clifford A…
It is not uncommon for influenza viruses to develop genetic mutations that make them less susceptible to anti-flu drugs. However, these mutations usually come at a cost to the virus, weakening its ability to replicate and to spread from one person to another…
In an article published online today in the journal Urologic Oncology, urologist Ralph de Vere White and medical oncologist Primo Lara, Jr. of the UC Davis Comprehensive Cancer Center describe a framework for urology and medical oncology interactions to enhance patient care, improve outcomes and yield clinical research advances…
The (REiNS) Collaboration was formed to achieve consensus regarding the design of clinical trials for treatments of NF and related disorders, with a focus on developing a standard set of appropriate and meaningful outcome measures. "This supplement presents the initial progress of several of the working groups and includes the first series of consensus recommendations for NF clinical trial endpoints by the REiNS International Collaboration," according to an introduction by Dr Scott R. …
Cell-cycle Cells in all organisms grow and divide into two daughter cells by an ordered sequence of events called "cell cycle." Basically , the cells have to complete four main processes during the cell cycle : growth ( G1 and G2 phases ) , doubling the DNA ( S phase ) , segregate chromosomes ( M phase , mitosis) and divide ( cytokinesis ) . …
For centuries, silica has been known to cause lung disease (silicosis). Evidence that silica causes lung cancer has been more recent, accumulating over the last several decades. Writing in CA: A Cancer Journal for Clinicians, Kyle Steenland, PhD, at the Rollins School of Public Health at Emory University in Atlanta, and Elizabeth Ward, PhD, of the American Cancer Society highlight three important developments that hold potential to prevent illness and death from silica exposure at work…
Dobek is part of a research team, headed by Dr. Kerri Winters-Stone, that found that the bone benefit from one year of such training could be maintained, even with less exercise, up to a year later, which could help prevent bone fractures in the long run. …
"There are many prognostic indices, but until now none meant to be used immediately upon hospital admission," says Stacy Fischer, MD, CU Cancer Center investigator and assistant professor of internal medicine at the University of Colorado School of Medicine. "Basically, with five criteria — none of which require obtaining labs or data gathering — we can accurately predict who is at low, medium and high risk for death within a year," says Jeanie Youngwerth, MD, CU Cancer Center investigator and Palliative Care specialist at the University of Colorado Hospital and School of Medicine. …
The journal Blood has published a new study on a drug candidate for multiple myeloma, a form of cancer that affects about one per cent of all tumour patients, with some 600 people a year developing the disease in Sweden. …