Tag Archives: publication

Classic signaling pathway holds key to prostate cancer progression

Although it is well established that the androgen receptor is important for prostate cancer progression, it is unclear what drives this process. Frigo and his team demonstrated in this study that androgens take control of the AMPK signaling cascade, a master regulator of metabolism, to increase prostate cancer cell growth. "The androgen signaling cascade is important for understanding early and late-stage prostate cancer progression. …

Increased attention needed for cancer risk from silica

For centuries, silica has been known to cause lung disease (silicosis). Evidence that silica causes lung cancer has been more recent, accumulating over the last several decades. Writing in CA: A Cancer Journal for Clinicians, Kyle Steenland, PhD, at the Rollins School of Public Health at Emory University in Atlanta, and Elizabeth Ward, PhD, of the American Cancer Society highlight three important developments that hold potential to prevent illness and death from silica exposure at work…

Chronic diseases hinder good cancer survival rates

How much diseases such as diabetes, COPD (chronic obstructive pulmonary disease), arthritis, depression and cardiovascular disease mean for cancer survival depends on the type of cancer; but the overall picture is the same. Other diseases have a strong negative impact on both the one and five-year survival rate. For example, for breast cancer the five-year survival rate for patients without other diseases is 83 percent. For patients with one or two other chronic diseases the survival rate is 64 percent, while it is 50 percent for those with three or more diseases. …