Dr. John S. Kuo and colleagues of University of Wisconsin School of Medicine and Public Health, Madison, evaluated two “tumor-selective” fluorescent agents — called CLR1501 and CLR1502 — for their ability to differentiate brain tumors from normal brain tissue in mice…
The key to the advance is a new invention, called the SunTag, a series of molecular hooks for hanging multiple copies of biologically active molecules onto a single protein scaffold used to target genes or other molecules. Compared to molecules assembled without these hooks, those incorporating the SunTag can greatly amplify biological activity. …
The key to the advance is a new invention, called the SunTag, a series of molecular hooks for hanging multiple copies of biologically active molecules onto a single protein scaffold used to target genes or other molecules. Compared to molecules assembled without these hooks, those incorporating the SunTag can greatly amplify biological activity. …
At the heart of this pathway lies PPARγ (peroxisome proliferation-activated receptor gamma), a protein that regulates glucose and lipid metabolism in normal cells. Researchers demonstrated that by activating PPARγ with antidiabetic drugs in lung cancer cells, they could stop these tumor cells from dividing. “We found that activation of PPARγ causes a major metabolic change in cancer cells that impairs their ability to handle oxidative stress,” said Dr…
By clarifying which patients are at highest risk for reduced sperm production as adults, researchers expect the findings to eventually increase use of pre-treatment fertility preservation methods such as sperm banking. The study involved drugs called alkylating agents that are widely used to treat a variety of pediatric cancers. …
source : http://www.sciencedaily.com/releases/2014/02/140206111420.htm
"The shape of the particles really seems to matter because the stretched, ellipsoidal particles we made performed much better than spherical ones in activating the immune system and reducing the animals’ tumors," according to Jordan Green, Ph.D., assistant professor of biomedical engineering at the Johns Hopkins University School of Medicine and a collaborator on this work. A summary of the team’s results was published online in the journal Biomaterials on Oct. 5. According to Green, one of the greatest challenges in the field of cancer medicine is tracking down and killing tumor cells once they have metastasized and escaped from a tumor mass…
source : http://www.foxnews.com/health/2013/06/25/fda-gives-go-ahead-for-two-new-cigarettes-rejects-four/
Green veggies have long been hailed as the go-to good-for-you food, but dark fruits, veggies, and grains are nutritional powerhouses, too. Their color comes from anthocyanins, plant pigments that may help lower the risks of diabetes, heart disease, and cancer. In fact, “black foods have more antioxidants than light-colored foods because of their high pigment content,” said Cy Lee, a professor of food chemistry at Cornell University in Ithaca, New York. Can’t find one of these deep-hued superfoods at your local supermarket? Try natural-foods stores and ethnic groceries. Black rice Brown rice is good for you, but black rice is even better. That’s because the bran hull contains significantly higher amounts of vitamin E, which bolsters the immune system and protects cells from free radical damage. In fact, black rice contains more anthocyanin antioxidants than blueberries, according to a study from the Louisiana State University Agricultural Center. Health.com: Superfood Secrets for a Long and Healthy Life Black lentils These legumes are loaded with iron: One cup has about 8 milligrams, getting you almost halfway to the daily requirement of 18 milligrams for women. Lentils also boast high levels of soluble fiber, which may not only lower your cholesterol, but could also improve immune function, according to a new University of Illinois study. Blackberries Polyphenols found in dark berries may help reduce cognitive decline in older age by cleaning up cells that impair brain function, researchers at the Human Nutrition Research Center on Aging in Boston say. Blackberries are also hugely fiber-rich—one cup has almost 8 of the 25 grams you need daily. Health.com: Need More Fiber? Eat These Foods Black beans The dark skins of these beans are packed with bioflavonoids—potent plant-based nutrients that may protect against cancer, research out of Cornell University reveals. Black soybeans Move over, edamame. A Korean study found that eating black soybeans can help reduce the risk of thrombosis—a type of blood clot that’s potentially fatal—even more than yellow or green soybeans. And all soybean oil contains alpha-linolenic acid, a type of omega-3 fatty acid that may reduce the risk of heart disease. Health.com: The 10 Best Foods for Your Heart Black tea Green and white teas get all the health hype, but good old black tea has its perks, too. It contains theaflavins—antioxidants that a study from Rutgers University in New Jersey suggests may improve recovery from muscle soreness after intense exercise. Drinking black tea may also lower your risk of having a heart attack. This article originally appeared on Health.com.source : http://www.foxnews.com/health/2013/06/15/black-is-new-green-6-surprising-superfoods/
A New York man living in Tulsa went to get a nose job with a well-established Tulsa plastic surgeon and five years later does not have a nose. Dr. Angelo Cuzalina is known across Green County, Okla., for his plastic surgery. The Oklahoma Medical Board does not show any complaints in his history. He is listed as president of the American Board of Cosmetic Surgery. “I had the first surgery and suffered some breathing problems, nothing too bad, but it made it hard to exercise and sleep,” said Thakkar. He went back, again and again. Between 2006 and 2007 he had eight surgeries. He then left Tulsa until 2011 and came back for more surgeries. He had several infections. Finally, during a surgery, Thakkar says Cuzalina cut off his nose. “He told me that there was an infection in there and since I was on the operating table and unconscious he had to make the decision,” said Thakkar. On August 31st, 2012 Cuzalina sent Thakkar a form stating he will no longer work on him, “… you are considered medically unstable. Because of your ongoing threats and harassment against my staff, my practice, and me personally…”  the statement read. It was around this time Thakkar told FOX23 News, he learned Cuzalina was recording their audio and video without letting Thakkar know that was happening during his visits to the office. The lawsuit filed by Thakkar's attorney, Paul Boudreaux states: “During this period, and in violation of plaintiff’s medical confidentiality and privileges, Cuzalina hired private investigators and attorneys, and secured hidden audio and video recordings of Plaintiff without Plaintiff's permission or knowledge, in violation of the law and Plaintiff's reasonable expectations of privacy.” “In December of 2011, in the medical record he (Dr. Cuzalina) wrote I am suicidal, but at the same time the medication he is giving me it could easily kill a couple human beings,” said Thakkar. The lawsuit details those drugs: “.. prescribed an excessive amount of medication, enough to kill the patient, if taken, including but not limited to Loratab, Ambien, Valilum, and Oxycodone.” “I have more than 3,000 injections, pain pills and stuff so my liver is pretty much fried,” said Thakkar. FOX23 News learned of Thakkar's story on Friday and called to interview with Cuzalina's attorney, Tim Best. After a few conversations, Best said they are not comfortable doing an interview because they need a signed medical release to speak about Thakkar's medical history. Click for more from Fox News 23. source : http://www.foxnews.com/health/2013/06/07/man-without-nose-files-lawsuit-against-tulsa-plastic-surgeon/