The Sydney-based research team has found a gene that drives the aggressive disease, and hopes to find a way to ‘switch it off’. The aggressive form of triple-negative breast cancer appears to arise from stem cells, while the more benign form appears to arise from specialised cells. …
In a revolutionary approach the researchers from the Cancer Research UK Cambridge Institute made the discovery by combining images from cancer samples with genetic data. …
The results of a Cancer Research UK trial involving more than 1,000 people are being presented at the National Cancer Research Institute’s annual conference in Liverpool. …
Cancer arises due to genetic changes which cause normal cells to develop into tumors. As we learn more about breast cancer, we are seeing that it is not one single disease — the mutations in the genes that cause different cancers are not alike, and this is why tumors respond differently to treatment and grow at different rates. Currently, there are two key markers that clinicians use to predict response to treatments. Spotting the trends in tumor genetics and creating a system to diagnose tumor types is a primary objective of cancer scientists. …
With 35,000 new cases every year in the UK, and around 10,000 deaths, prostate cancer is the second most common cancer in men worldwide. Rates are higher in developed countries, which some experts believe is linked to a Westernised diet and lifestyle. To assess if following dietary and lifestyle recommendations reduces risk of prostate cancer, researchers at the Universities of Bristol, Cambridge and Oxford looked at the diets and lifestyle of 1,806 men aged between 50 and 69 with prostate cancer and compared with 12,005 cancer-free men. …
In a study run through the international PALB2 Interest Group a team of researchers from 17 centres in eight countries led by the University of Cambridge analysed data from 154 families without BRCA1 or BRCA2 mutations, which included 362 family members with PALB2 gene mutations. The effort was funded by the European Research Council, Cancer Research UK and multiple other international sources. Women who carried rare mutations in PALB2 were found to have on average a 35% chance of developing breast cancer by the age of seventy…
source : http://www.sciencedaily.com/releases/2014/06/140611132034.htm
source : http://www.sciencedaily.com/releases/2014/05/140531090645.htm
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source : http://www.sciencedaily.com/releases/2014/03/140324090320.htm