Tag Archives: liverpool

Gene ‘switches’ could predict when breast cancers will spread to the brain — ScienceDaily

The researchers, based at the University of Wolverhampton, studied 24 breast cancers that had spread to the brain, along with samples from the original breast tumour, and found a handful of genes with faulty switches. Crucially, two of the genetic switches became faulty early on in the development of breast cancer, suggesting they may be an early warning signal for tumours that will spread to the brain. The scientists are now working to develop a blood test that might be able to detect these signals at an early stage, before the disease has spread. …

Scientists uncover potential drug to tackle ‘undruggable’ fault in third of cancers

A team of scientists at the Max Planck Institute of Molecular Physiology in Germany has uncovered a new strategy and new potential drug to target an important signalling protein in cells called Ras, which is faulty in a third of cancers. When the Ras protein travels from the centre of a cell to the cell membrane, it becomes ‘switched on’ and sends signals which tell cells to grow and divide. …

Gene ‘switches’ could predict when breast cancers will spread to the brain

The researchers, based at the University of Wolverhampton, studied 24 breast cancers that had spread to the brain, along with samples from the original breast tumour, and found a handful of genes with faulty switches. Crucially, two of the genetic switches became faulty early on in the development of breast cancer, suggesting they may be an early warning signal for tumours that will spread to the brain. The scientists are now working to develop a blood test that might be able to detect these signals at an early stage, before the disease has spread. Up to 30 per cent of breast cancers will eventually spread to the brain, often many years after the first tumour was treated…

Half of smokers using Liverpool Stop Smoking Services used e-cigs

The data — presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool — also highlights that smokers are more likely to try e-cigarettes if they feel more confident that the products are safer than tobacco smoking. Researchers from the University of Liverpool quizzed more than 320 smokers from the Roy Castle FagEnds study to understand the number of people who used e-cigarettes and what smokers thought about the products. Smokers appear undecided towards e-cigarettes, possibly due to the widely documented uncertainties about safety and effectiveness in helping smokers to successfully break their addiction. Some also viewed using e-cigarettes as an extension of smoking and perceived them as an inferior tool for helping to quit smoking…

Patients with emergency-diagnosed lung cancer report barriers to seeing their GP

The study, carried out by researchers from the London Cancer Alliance (LCA) and King’s College London investigated around 130 patients who were diagnosed with lung cancer after attending as an emergency at one of seven hospitals in south and west London. Overall, nearly half of the patients reported that something had put them off going to the doctor, including difficulty making an appointment, not being able to see their usual doctor, not having confidence in the GP, and fear of what the doctor might find. About a fifth of all patients (18 per cent) said they had not realised that their symptoms were serious.A fifth of all patients — who tended to be older, poorer and more fearful of what the doctor might find — delayed going to their doctor with their symptoms for more than 12 weeks. Three-quarters of the patients had consulted their GP about their symptoms, and one fifth had seen a GP at least three times. …

Showcase of latest advances in medical imaging for revolutionary proton therapy cancer treatment

The University of Lincoln’s Professor Nigel Allinson MBE will deliver the keynote talk at the tenth International Conference on Position Sensitive Detectors. The conference, which takes place from 7th to 12th September 2014, features the latest developments in this field from leading researchers around the world. Professor Allinson leads the pioneering PRaVDA (Proton Radiotherapy Verification and Dosimetry Applications) project. He and his multinational team are developing one of the most complex medical instruments ever imagined to improve the delivery of proton beam therapy in the treatment of cancer…