Tag Archives: american

New therapy shown to improve progression-free survival and shrink tumors in rare cancer for the first time

The findings are potentially practice-changing for a historically "untreatable disease." Though uveal melanoma is rare — there are only 2,500 cases diagnosed in the United States each year — about half of patients will develop metastatic disease, and survival for patients with advanced disease has held steady at nine months to a year for decades. Researchers found that progression-free survival (PFS) in patients receiving selumetinib was nearly 16 weeks and 50 percent of these patients experienced tumor shrinkage, with 15 percent achieving major shrinkage. Patients receiving temozolomide, the current standard chemotherapy, had seven weeks of PFS and no tumor shrinkage. …

New technique alleviates painful bone metastases, study suggests

During the procedure, known as MR-guided focused ultrasound, doctors direct a concentrated beam of energy to specific nerve endings that are causing pain in bone metastases. These patients typically have a significant amount of discomfort — half of study participants rated their pain at least a 7 out of 10 — but within a handful of days, most said they felt significant relief. Although Fox Chase patients received local anesthesia during the procedure, the most commonly reported side effect was pain — which can often be alleviated with additional anesthesia, says study author Joshua Meyer, MD, attending physician in the Radiation Oncology Department at Fox Chase. "That’s temporary pain, which is gone as soon as the procedure is over," he says…

Bicycle helmet laws linked to fewer child deaths

U.S. states that require children and teenagers to wear helmets report fewer deaths involving bicycles and cars, according to a new study. Researchers analyzed the number of U.S. bicycle deaths between 1999 and 2010 and found that states with bicycle helmet laws reported about 20 percent fewer bike-related fatalities among people younger than 16 years old. “The impetus is that when you make it a law, parents realize it's important and parents get their kids to do it,” said Dr. William Meehan, the study's lead author from Boston Children's Hospital. About 900 people die as a result of bicycle crashes every year in the U.S. and about three quarters of those are from head injuries, according to Meehan and his colleagues. Previous research has found that wearing a helmet may reduce a person's risk of a head or brain injury by up to 88 percent, but few studies have looked at the effect of helmet laws on national injury and fatality rates. Using a national database that tracks the number of traffic-related deaths in the U.S., the researchers compared the number of children and teenagers killed while riding their bicycles in the 16 states that enacted helmet laws around the start of the study in 1999 to states without helmet laws. In 1999, only 16 states had helmet laws and the overall rate of bicycle-related child deaths in the U.S. was 4 per million. Between January 1999 and December 2010, there were 1,612 bicycle-related deaths among children younger than 16 years old, the researchers found. During that time, states with helmet laws had 2 bicycle-related deaths for every 1 million children younger than 16 years old. That compares to 2.5 deaths for every 1 million children in states without helmet laws. After adjusting for other state characteristics known to be associated with traffic-related deaths - such as household income, and drunk or elderly driving laws - the states with helmet laws still had fewer reported deaths in that age group. “We would recommend that any state that doesn't have a mandatory bicycle helmet law for children consider one or institute one,” Meehan said. Dr. Frederick Rivara, a professor of pediatrics at the University of Washington and Seattle Children's Hospital, said it's nice that the new study shows states with helmet laws report fewer deaths, but he said it's important to remember that helmets can also prevent serious injuries. “Bicycle fatalities represent only the very tip of the iceberg,” said Rivara, who has studied bicycle helmet safety but was not involved with the new research. The American Academy of Pediatrics currently recommends that children wear a helmet approved by the Consumer Product Safety Commission every time they ride a bicycle. “Helmets are very effective. They're cheap, they're light, they're comfortable and they work,” Rivara said.source : http://www.foxnews.com/health/2013/05/30/bicycle-helmet-laws-linked-to-fewer-child-deaths/

Is there a hidden scandal lurking in ObamaCare?

America, we are in trouble – and we better wake up and act.   Just look at the state of affairs in our country today.  We are seeing scandal after scandal, with the Benghazi controversy, the IRS targeting of conservative groups, and the freedom of the press being challenged by the Department of Justice. The word scandal is defined by the Oxford Dictionary as “an action or event regarded as morally or legally wrong and causing general public outrage.”  I think the implementation of ObamaCare fulfills that definition. I remember back in 2010 when then-Speaker of the House Nancy Pelosi made her infamous remark about the Affordable Care Act, saying “we have to pass the bill so that you can find out what’s in it....” Well the bill has been passed, and now we see what’s in it: An utter mess with incomprehensible rules. If we compare the assertions the president made about ObamaCare when it was first introduced to the current bill as it has been passed today, we find that all the president’s guarantees regarding ObamaCare are not there.   The truth of the matter is that we were not fully informed.  For example, President Obama maintained that this bill would lower the cost of health care, especially in regards to insurance premiums.  That is simply not true.  Many different analyses clearly show that in some markets, insurance premiums can increase as high as 30 to 40 percent. One of the main reasons for this increase can be attributed to all the hidden taxes that this bill contains, which the insurance industry will likely pass on to consumers.   Another false guarantee given by the administration was that individuals would be able to keep their doctors and current level of service through ObamaCare.  Again, this is not true. The so-called insurance exchanges being set up in many states by the federal government will most likely create a non-competitive environment, meaning patients who cannot afford other types of insurance will be forced to buy insurance from the government.  And if their current doctors are not willing to participate in that single-payer health care system, these patients will ultimately lose the guarantee of keeping their own doctors. So what does this all mean? It means that if everything goes according to the president’s plan, the health care landscape is going to completely change over the next decade. A potential scenario is that private doctors will be employees of one large health care system. Health standards such as maintaining an ideal weight and eliminating habits like drinking alcohol and soda will be placed on families so that they can qualify for health care.  So in other words, your individual freedom will be targeted. I know many people argue that it’s better if everyone has health insurance and maintains a healthy lifestyle.  Yes it is, but I still believe that an individual’s health care should not be dictated by the government. Instead it should be a choice made by the individual and his or her health provider. Many senior politicians and consultants have found as of late that ObamaCare is a train wreck.  And yet, the person in charge of implementing ObamaCare, United States Secretary of Health and Human Services Kathleen Sebelius, continues to drive the train forward.  Rather than work with leaders who are suggesting changes ,she has decided to enlist the help of the private sector in getting donations to help fund ObamaCare.   Many have questioned this move, but one thing Secretary Sebelius knows is how to organize her community of followers.  Recently, she has teamed up with Nancy-Ann DeParle, former director of the White House Office of Health Reform, placing her in charge of asking insurance companies to donate $1 million or more to Enroll America, a non-profit organization promoting enrollment in the subsidized insurance markets, according to a report from Politico. You see, folks, ObamaCare is all about politics and control, and to me, that is a formula for disaster.  This is something that should not be taken for granted but rather openly evaluated by the American public.source : http://www.foxnews.com/health/2013/05/29/is-there-hidden-scandal-lurking-in-obamacare/

Pork industry hunts for deadly pig virus

The sudden and widespread appearance of a swine virus deadly to young pigs - one never before seen in North America - is raising questions about the bio-security shield designed to protect the U.S. food supply. The swine-only virus, the Porcine Epidemic Diarrhea Virus (PEDV), poses no danger to humans or other animals, and the meat from infected pigs is safe for people to eat. Though previously seen in parts of Asia and Europe, the virus now has spread into five leading hog-raising U.S. states. How it arrived in the United States remains a mystery. While the U.S. imports millions of pigs each year from Canada, it imports pigs from virtually no other country, and no Canadian cases of PEDV have been confirmed. Veterinarians and epidemiologists say pigs are infected through oral means, and that the virus is not airborne and does it not occur spontaneously in nature. In recent years, with the emergence of dangerous pathogens such as H1N1, also known as swine flu, and bovine spongiform encephalopathy (BSE) or mad cow disease, the United States and other countries have sought to secure defenses both on the farm and at the national borders to protect against barnyard epidemics. “We're just trying to get a handle on what's happening,” said Tom Burkgren, executive director of the American Association of Swine Veterinarians. “It's like drinking water out of a fire hose. We're getting hits from all over the place.” Overall numbers of confirmed cases and mortality rates are not yet available, though anecdotal evidence suggests there are devastating losses for farms that are hit. “If you've got it, it's bad,” said Mark Greenwood, vice president of agri-business capital at AgStar Financial Services, who said none of his clients have been affected. “I spoke to a farmer in the Midwest who had it show up in a 2,000-head barn of pigs, and had a 40 percent death loss.” A spokeswoman for U.S. Department of Agriculture's Animal and Plant Health Inspection Service told Reuters the agency is working with state agencies and pork industry officials to discover where the virus originated. THE VIRUS SPREADS Confirmed cases have been reported in five hog-raising states including Iowa, the largest U.S. hog producer with 20 million hogs, according to the USDA. While only seven farms have had confirmed cases since May 17, more cases are expected as labs sift through samples, say sources investigating the outbreak. Colorado, Indiana, Illinois and Minnesota reportedly have positive tests for PEDV, according to state veterinarians and agriculture department officials, and the National Veterinary Services Laboratory in Ames, Iowa. PEDV, most often fatal to very young pigs, causes diarrhea, vomiting and dehydration. It also sickens older hogs, though their survival rate tends to be high. Known as a “coronavirus” because of the crown-like spikes on its surface, the virus afflicted China in recent years and killed more than 1 million piglets. PEDV is spread most commonly by pigs ingesting contaminated feces. Investigators are focused on physical transmission, perhaps a PEDV infected pig, equipment marred with feces, or even a person wearing dirty boots or with dirty nails. The mystery about how the virus entered the United States is raising concern about potential holes in the bio-security shield designed to protect the U.S. food and farming sectors. “Like everything else, we screw up from time to time,” said Ronald L. Plain, professor of agricultural economics at University of Missouri in Columbia, Missouri. “We know so little about the transmittal of this virus. We can't be sure if it's happening because of something we're supposed to do right and didn't - or by some mechanism we don't know that we're supposed to do differently.” Initial reporting about the virus may have been delayed, say sources, because its symptoms can be confused with a more common malady, transmissible gastroenteritis (TGE). Also, states are not required to report cases of PEDV to the federal government, and farmers are not required to report to state veterinarians. As part of its assessment of the situation, USDA will email epidemiological surveys to swine veterinarians who are dealing cases of PEDV. Meanwhile, the veterinarians are sending samples to diagnostic labs, where technicians are scrambling gathering the tools needed to check the samples for PEDV - supplies many labs did not have prior to the outbreak. While most farmers are taking a wait-and-see approach, some told Reuters they are turning away unnecessary visitors and double checking to ensure their safety protocols are being followed. LOOKING NORTH The search for leads also has turned to the nation's borders and ports of entry - specifically, Canada, where the United States imported 5.7 million head of live hogs last year. Canada has never had a confirmed case of the virus, though it does not test for it, government officials said. “Canada has very effective import measures in place to address this risk,” said Dr. Rajiv Arora, senior staff veterinarian for the Canadian Food Inspection Agency's foreign animal disease section. Canada can import live breeding pigs, under permits, from either the United States or the European Union, Arora said. The animals are quarantined by CFIA for a period of time, then inspected and tested - although not for PEDV - before released. Canada imported C$1.7 million ($1.6 million) worth of live swine in 2012, including both slaughter-ready and breeder pigs, according to Canada's Agriculture Department. CHINA HARD HIT Veterinarians and agricultural epidemiologists in the United States are drawing grim lessons from the devastating effect PEDV has had in other countries where it has hit. The first reports of suspected PEDV came in 1971 in the United Kingdom. As years passed, PEDV spread across parts of Europe and Asia. Veterinary researchers later concluded that lax bio-security measures contributed to PEDV's spread in Asia. One of the worst known outbreaks of the virus hit China's pig herds in late 2010, according to the Centers for Disease Control and Prevention's Emerging Infectious Diseases Journal. Vaccines had limited effectiveness and PEDV over ran southern China killing more than 1 million piglets. The death rate for virus-infected piglets ranged from 80 percent to 100 percent. Biosecurity measures in the U.S. food supply have been beefed up over the years, and especially after the outbreaks of mad cow disease and swine flu. Both outbreaks posed risks to human health. Today, trucks carrying live animals are supposed to be cleaned before entering and leaving farms. At commercial hog operations, visitors routinely shower and change clothing before stepping into a barn. Overseas visitors typically wait several days before being in the presence of a commercially raised hog. But the food shield is not impermeable. “If it becomes clear that this is not a novel way for to be transmitted, and that there had to be physical contact, that's going to be a major concern,” said William Marler, a leading food-safety attorney. “It means that there was a failure in the system.”source : http://www.foxnews.com/health/2013/05/29/pork-industry-hunts-for-deadly-pig-virus/

H1N1 flu outbreak kills 17 in Venezuela

An outbreak of H1N1 flu has killed 17 people in Venezuela and infected another 250, private media and local authorities said on Monday. H1N1, often referred to as swine flu, was a flu strain that swept around in the world in a 2009/2010 pandemic. “We're suffering a tail-end of the pandemic,” a former Venezuelan health minister, Rafael Orihuela, told a local TV station, commenting on the widespread reports of 17 deaths in the South American nation of 29 million people. Most of the cases were in border states near Colombia. Venezuela's government has not confirmed the figures given by media and local health authorities. But officials said high-risk groups had largely been immunized, with 3 million vaccinations carried out so far this year. The World Health Organization's (WHO) official data show 18,500 people were reported killed in the 2009/2010 H1N1 pandemic, but a study in The Lancet last year said the actual death toll may have been up to 15 times higher at more than 280,000.source : http://www.foxnews.com/health/2013/05/28/h1n1-flu-outbreak-kills-17-in-venezuela/

10 things you only ask Google

Click over to the history tab in your browser and scan what's there. We're going to bet there's at least one semi-embarrassing health question you've been trying to get to the bottom of, but would never breathe a word about to your doctor.  To help you save time (and face), we canvassed doctors across America about common embarrassing symptoms and guess what? None of them flinched. They also had some fascinating clues as to what might be causing them—and what you can do about it. Here, strange symptoms you'd rather not talk about—explained. Why do I pee when I run? “Exercise-induced incontinence is not uncommon in women, and it's usually caused by one of two factors: “1. Stress incontinence occurs when the pressure inside the abdomen exceeds the resistance at the neck of the bladder (for example: if the urethral sphincter muscle doesn't close with enough force). Running or other strenuous physical exercise could cause this increase in abdominal pressure and subsequent urinary leakage. (Sound familiar? See 11 Fixes For A Weak Bladder.) “2. The other main reason is bladder overactivity, where the muscles of the wall of the bladder squeeze when they should be relaxed (during bladder filling). This gives people a sense of urgency, and may cause them to leak urine. “If you're experiencing urine leakage with running or other physical exercise, I encourage you to seek help from a urologist or your primary health care provider.” —Dr. Tomas L. Griebling, professor and vice-chair of urology at the University of Kansas My thighs chafe when I walk. What's up? …

Sugary drinks tied to kidney stone risk

Adults who drink at least one sugar-sweetened drink a day are slightly more likely to develop kidney stones than people who rarely imbibe them, according to a new study. While the recommendation for kidney stone prevention has been to drink a lot of fluids, the study suggests that it's not just the amount of fluid but the type of drink that also matters. Dr. Gary Curhan, the senior author of the study, said patients often ask for dietary advice to help prevent kidney stones. While the recommendation has been to drink plenty of fluids, Curhan said, patients often ask, “what should I drink? There's a lot of lore out there.” To see whether the type of beverage might matter, Curhan, of the Channing Division of Network Medicine at Brigham and Women's Hospital, and his colleagues collected data from three massive surveys of nearly 200,000 people. The questionnaires surveyed participants every two to four years and asked about diet, lifestyle and health, including how much they drank certain beverages and whether they developed kidney stones. None of the people in the study had kidney stones at the start. They found that 159 out of every 100,000 people who drank a sugar-sweetened non-cola beverage, such as clear soda, less than once a week developed kidney stones, compared to 306 out of every 100,000 who drank soda daily. After accounting for other factors, that translated to a 33 percent greater chance of developing kidney stones. Frequent punch drinkers also had an 18 percent higher chance of developing kidney stones. For every 100,000 people who drank punch at least every day, 226 developed kidney stones, compared to 158 out of every 100,000 participants who had punch less than once a week. Curhan said that while the numbers of people developing kidney stones in each group are not enormously different, the increased risk spread across an entire population is quite big. “Sodas are so commonly used that even though the absolute rate doesn't look that different, if there's a huge number of people consuming it, then the magnitude on the public health can be quite substantial,” Curhan told Reuters Health. Other drinks, such as coffee, tea, wine, beer and orange juice were tied to a lower risk of developing kidney stones. For instance, 205 out of every 100,000 people who rarely drank coffee developed kidney stones, compared to 137 out of every 100,000 people who drank it daily. Just 96 out of every 100,000 people who drank red wine daily developed kidney stones, while 174 out of every 100,000 people who drank red wine less than once a week developed kidney stones. Curhan's study, published in the Clinical Journal of the American Society of Nephrology, follows others showing a link between stones and fructose, non-dairy calcium, vitamin C supplements and other factors. The new study doesn't prove cause-and-effect between certain drinks and kidney stones, but it's possible that sugar could be involved, Curhan said, because it might play a role in how the body handles calcium. Another possibility is that sugary drinks might be contributing to obesity, and obesity is also tied to a higher kidney stone risk, said Dr. Elaine Worcester, a professor at the University of Chicago, who was not part of the study. Despite the lack of proof of a cause-effect relationship, Worcester said “these kinds of studies are the best we have to give advice to our patients.”source : http://www.foxnews.com/health/2013/05/23/sugary-drinks-tied-to-kidney-stone-risk/

Inexpensive, accurate way to detect prostate cancer: At-home urine tests

After more than a decade of work, UC Irvine chemists have created a way to clearly identify clinically usable markers for prostate cancer in urine, meaning that the disease could be detected far sooner, with greater accuracy and at dramatically lower cost. The same technology could potentially be used for bladder and multiple myeloma cancers, which also shed identifiable markers in urine. "Our goal is a device the size of a home pregnancy test priced around $10…

Poliovirus vaccine trial shows early promise for recurrent glioblastoma

The treatment, developed at Duke and tested in an ongoing phase 1 study, capitalizes on the discovery that cancer cells have an abundance of receptors that work like magnets drawing the poliovirus, which then infects and kills the cells. The investigational therapy, known as PVSRIPO, uses an engineered form of the virus that is lethal to cancer cells, while harmless to normal cells. …