Category Archives: Cancer

Olive Oil 101: How to choose oils with the most health benefits

It is well known that extra virgin olive oil is good for the body – boosting heart health and even lowering the risk of certain kinds of cancer.  But not all olive oils are created equal. According to Nicholas Colman, the chief olive oil specialist at Eataly in New York City, olive oil has to be fresh in order to maintain its health advantages. “Even the best producer in the world – if their oil is old, you’re not going to reap the health benefits from it,” Coleman told FoxNews.com. Coleman said it’s important to pick your oil like you would pick your wine – taking into account when it was bottled, the kinds of olives that are in it, and the region from which it came. “When you taste a really, really great olive oil, you might notice a peppery finish build in the back of the throat – this tingle,” Coleman said. “And what causes that is oleocanthal, which is an antioxidant.  The more of that peppery burn you feel, the higher the presence of antioxidants in the oil and the healthier it is for the body.” Oils from Tuscany, Puglia and Sicily have the most antioxidants of the Italian extra virgin olive oils, Coleman said.  And price is an important factor too: Cheap olive oil from the grocery store may not cut it. “Usually they take olives from all over the world, and they buy oil that is left over at the end of the year,” Coleman said. “And they blend it all together and ship it to America.” While the oil’s color doesn’t affect its health benefits, Coleman said the bottle’s color does.  He advised picking a dark, glass bottle or tin, so the oil doesn’t photo-oxidize and degrade. And when you finally cook with your newly purchased olive oil in the kitchen, make sure to warm it slowly to preserve the antioxidants. For more information on how to choose the perfect olive oil, visit http://www.eataly.com/.source : http://www.foxnews.com/health/2013/05/19/olive-oil-101-how-to-choose-oils-with-most-health-benefits/

Victims claim Marines failed to safeguard water supply

CAMP LEJEUNE, N.C. – & A simple test could have alerted officials that the drinking water at Camp Lejeune was contaminated, long before authorities determined that as many as a million Marines and their families were exposed to a witch's brew of cancer-causing chemicals. But no one responsible for the lab at the base can recall that the procedure -- mandated by the Navy -- was ever conducted. The U.S. Marine Corps maintains that the carbon chloroform extract (CCE) test would not have uncovered the carcinogens that fouled the southeastern North Carolina base's water system from at least the mid-1950s until wells were capped in the mid-1980s. But experts say even this “relatively primitive” test -- required by Navy health directives as early as 1963 -- would have told officials that something was terribly wrong beneath Lejeune's sandy soil. A just-released study from the federal Agency for Toxic Substances and Disease Registry cited a February 1985 level for trichloroethylene of 18,900 parts per billion in one Lejeune drinking water well -- nearly 4,000 times today's maximum allowed limit of 5 ppb. Given those kinds of numbers, environmental engineer Marco Kaltofen said even a testing method as inadequate as CCE should have raised some red flags with a “careful analyst.” “That's knock-your-socks-off level -- even back then,” said Kaltofen, who worked on the infamous Love Canal case in upstate New York, where drums of buried chemical waste leaked toxins into a local water system. “You could have smelled it.” Biochemist Michael Hargett agrees that CCE, while imperfect, would have been enough to prompt more specific testing in what is now recognized as the worst documented case of drinking-water contamination in the nation's history. “I consider it disingenuous of the Corps to say, `Well, it wouldn't have meant anything,”' said Hargett, co-owner of the private lab that tried to sound the alarm about the contamination in 1982. “The levels of chlorinated solvent that we discovered ... they would have gotten something that said, `Whoops. I've got a problem.' They didn't do that.” Trichloroethylene (TCE), tetrachloroethylene (PCE), benzene and other toxic chemicals leeched into ground water from a poorly maintained fuel depot and indiscriminate dumping on the base, as well as from an off-base dry cleaner. Nearly three decades after the first drinking-water wells were closed, victims are still awaiting a final federal health assessment -- the original 1997 report having been withdrawn because faulty or incomplete data. Results of a long-delayed study on birth defects and childhood cancers were only submitted for publication in late April. Many former Lejeune Marines and family members who lived there believe the Corps still has not come clean about the situation, and the question of whether these tests were conducted is emblematic of the depth of that mistrust. Marine Corps officials have repeatedly said that federal environmental regulations for these cancer-causing chemicals were not finalized under the Safe Drinking Water Act until 1989 -- about four years after the contaminated wells had been identified and taken out of service. But victims who have scoured decades-old documents say the military's own health standards should have raised red flags long before. In 1963, the Navy's Bureau of Medicine and Surgery issued “The Manual of Naval Preventive Medicine.” Chapter 5 is titled “Water Supply Ashore.” “The water supply should be obtained from the most desirable sources which is feasible, and effort should be made to prevent or control pollution of the source,” it reads. At the time, the Defense Department adopted water quality standards set by the U.S. Public Health Service. To measure that quality, the Navy manual identified CCE “as a technically practical procedure which will afford a large measure of protection against the presence of undetected toxic materials in finished drinking water.” Also referred to as the “oil and grease test,” CCE was intended to protect against an “unwarranted dosage of the water consumer with ill-defined chemicals,” according to the Navy manual. The CCE standard set in 1963 was 200 ppb. In 1972, the Navy further tightened it to no more than 150 ppb. In response to a request from The Associated Press, Capt. Kendra Motz said the Marines could produce no copies of CCE test results for Lejeune, despite searching for “many hours.” “Some documents that might be relevant to your question may no longer be maintained by the Marine Corps or the Department of the Navy in accordance with records management policies,” she wrote in an email. “The absence of records 50 years later does not necessarily mean action was not taken.” But the two men who oversaw the base lab told the AP they were not even familiar with the procedure. “A what?” asked Julian Wooten, who was head of the Lejeune environmental section during the 1970s, when asked if his staff had ever performed the CCE test. “I never saw anything, unless the (Navy's) preventive medicine people were doing some. I don't have any knowledge of that kind of operation or that kind of testing being done. Not back then.” “I have no knowledge of it,” said Danny Sharpe, who succeeded Wooten as section chief and was in charge when the first drinking water wells were shut down in the mid-1980s. “I don't remember that at all.” Wooten was an ecologist, and Sharpe's background is in forestry and soil conservation. But Elizabeth Betz, the supervisory chemist at Lejeune from 1979 to 1995, was also at a loss when asked about the CCE testing. “I do not remember any such test being requested nor do I remember seeing any such test results,” Betz, who later worked for the U.S. Environmental Protection Agency's national exposure branch at Research Triangle Park outside Raleigh, wrote in a recent e-mail. Hargett, the former co-owner of Grainger Laboratories in Raleigh, said he never saw any evidence that the base was testing and treating for anything beyond e coli and other bacteria. “That was a state regulation ... that they had to maintain a sanitary water supply,” he said. “And they did a good job at that.” Motz, the Marine spokeswoman, told the AP that the method called for in the manual would not have detected the toxins at issue in the Camp Lejeune case. “The CCE method includes a drying step and a distillation (evaporation) step where chloroform is completely evaporated,” she wrote in an email. These volatile organic compounds, “by their chemical nature, would evaporate readily as well,” she wrote. ATSDR contacted the EPA about the “utility” of such testing and concluded it would be of no value in detecting TCE, PCE, or benzene, Deputy Director Tom Sinks wrote in an email to members of a community assistance panel on Lejeune. “It is doubtful that the weight of their residue would be detectable when subjected to this method,” Sinks wrote. Kaltofen, a professor at Worcester Polytechnic Institute in Massachusetts, acknowledged that CCE is “a relatively primitive test.” But in addition to the water's odor, Kaltofen said, “there are some things that a careful analyst would easily have noticed.” Hargett agreed. “It would have prompted you to simply say, `Wow. There is something here. Let's do some additional work,”' he told the AP. Any “reputable chemist ... would have raised their hands to the person responsible and said, `Guys. You ought to look at this. There's more here.”' The Marines have said such high readings were merely spikes. But Kaltofen countered that, “You can't get that level even once without having a very serious problem ... It's the worst case.” In a recent interview, Wooten told the AP that he knew something was wrong with the water as early as the 1960s, when he worked in the maintenance department. “I was usually the first person in in the big building that we worked in,” he said. “And I'd cut the water on and let it run, just go and flush the commodes and cut the water on and let it run for several minutes before I'd attempt to make coffee.” Wooten said he made repeated budget requests for additional equipment and lab workers. But as Betz told a federal fact-finding group, “the lab was very low on the priority list at the base.” She said her group -- the Natural Resources and Environmental Affairs Department -- was “like the `red headed stepchild.”' Even a series of increasingly urgent reports from an Army lab at Fort McPherson, Ga., beginning in late 1980, failed to prompt any real action. “WATER HIGHLY CONTAMINATED WITH OTHER CHLORINATED HYDROCARBONS (SOLVENTS!)” cautioned one memo from the Army lab in early 1981. Because the base water system drew on a rotating basis from a number of different wells, subsequent tests showed no problems, and officials chalked these “interferences” up to flukes. One base employee told the fact-finding group that in 1980, “they simply did not have the money nor capacity” to test every drinking-water well on the base. “This type of money would have cost well over $100,000, and their entire operating budget was $100,000,” the employee said, according to a heavily redacted summary obtained by the AP from the Department of Justice through the Freedom of Information Act. “However, they did not do the well testing because they did not think they needed to.” So, from late 1980 through the summer of 1982, the former employee told investigators, “this issue simply laid there. No attempts were made to identify ground contamination” at Hadnot Point or Tarawa Terrace, where most of the enlisted men and their families lived. It wasn't until a letter from Grainger in August 1982 reported TCE levels of 1,400 ppb that any kind of widespread testing began. Though the EPA did not yet enforce a limit for TCE at the time, the chemical had long been known to cause serious health problems. “That is when the light bulb went off,” Sharpe told federal investigators in a 2004 interview, obtained by the AP. “That is when we connected the tests of the 1980, 1981, and 1982 time period where traces of solvents were detected to this finding.” Still, it was not until the final weeks of 1984 that the first wells were closed down. Between the receipt of that 1982 letter and the well closures, the employee told the fact-finding group, “they simply dropped the ball.” Each year of delay meant an additional 10,000 people may have been exposed, according to Marine estimates. Municipal utilities around the country were using far more sophisticated tests to detect much lower contaminate levels, said Kaltofen, while the people at Camp Lejeune were doing “the bare minimum. And it wasn't enough.” Last year, President Obama signed the Camp Lejeune Veterans and Family Act to provide medical care and screening for Marines and their families, but not civilians, exposed between 1957 and 1987 -- although preliminary results from water modeling suggest that date be pushed back at least another four years. The law covers 15 diseases or conditions, including female infertility, miscarriage, leukemia, multiple myeloma, as well as bladder, breast, esophageal, kidney and lung cancer. Jerry Ensminger, a former drill sergeant, blames the water for the leukemia that killed his 9-year-old daughter, Janey, in 1985. He and Michael Partain -- a Marine's son who is one of at least seven dozen men with Lejeune ties diagnosed with a rare form of breast cancer -- have scoured the records, and he thinks the Corps has yet to accept responsibility for its role in this tragedy. “If I hadn't dug in my heels,” Ensminger said, “this damned issue would have been dead and buried along with my child and everybody else's.”source : http://www.foxnews.com/health/2013/05/18/victims-claim-marines-failed-to-safeguard-water-supply/

Can you think yourself well?

What if you had the ability to heal your body just by changing how you think and feel? I know it sounds radical, coming from a doctor. When people are doing everything “right”—eating veggies, avoiding red meat and processed foods, exercising, sleeping well and so forth—we should expect them to live long, prosperous lives and die of old age while peacefully slumbering, right? So why is it that so many health nuts are sicker than other people who pig out, guzzle beer and park in front of the TV…

Flesh-eating bacteria victim Aimee Copeland gets new bionic hands

Last summer, the nation was captivated by the story of Aimee Copeland, a University of West Georgia graduate student who lost both her hands and a leg to a terrible bout with flesh-eating bacteria, which she contracted during a zip-lining accident.   Now, a little over a year later, 25-year-old Copeland has been fitted with a new pair of prosthetic hands, which allow her to wipe down tables, fold towels and even straighten her hair, WLTX.com reported.   Thanks to a gift from Touch Bionics in Hilliard, Ohio, Copeland is the first woman in the world with bilateral upper limb amputations to be fitted with iLimb Ultra Prosthetic Hands.  According to the company, the prosthetic hands cost $100,000 each, but Touch Bionics gave them to Copeland free of charge, as she had run out of insurance to pay for them herself. To date, the iLimb hands are the most advanced and most versatile high-tech prosthetic hands available, and Copeland has spent the past week in Hilliard getting them fitted and learning how to use them.  In a video from WXIA of Columbus, Ohio, she was able to delicately pick up a single M&M. “It feels amazing, because you know, with the other arms I had, they really didn’t feel like an extension of my body,” Copeland told WXIA.  “This just feels very freeing; it’s more light-weight. And the hand actually… it seems like this could be my actual hand.” Copeland’s ordeal began in May 2012, when she was enjoying a trip kayaking down a creek with some of her friends in Carrollton, Ga.  But when Copeland stopped to ride on a homemade zip line along the water, the line snapped and cut a large gash in her left calf.   Doctors ultimately had to staple her leg up with 22 staples, and they told her to take pain medication.  But the pain did not subside, so a friend drove Copeland to the emergency room the next day, where doctors diagnosed her with necrotizing fasciitis – the infection and destruction of a layer of tissue right underneath the skin.  The bacteria had entered Copeland’s body through the gash she had received during the zip-lining accident.   Despite her initial odds of survival being “slim to none,” then 24-year-old Copeland eventually pulled through, but both her hands and her entire left leg had to be amputated in order to ensure her survival.  After two months in the hospital and two months of rehabilitation, Copeland returned to her renovated home in Snellville, Ga., where she began physical therapy. Click for more from WLTX.com.source : http://www.foxnews.com/health/2013/05/17/flesh-eating-bacteria-victim-aimee-copeland-gets-new-bionic-hands/

What you need to know about new PSA screening guidelines

Recently, the American Urological Association (AUA) announced new guidelines for prostate specific antigen (PSA) testing.  These guidelines were designed to help urologists, and ultimately patients, reduce prostate cancer mortality by making informed screening decisions.  These recommendations were based on comprehensive literature reviews and the strength of the existing evidence.   Here is what you need to know: • The AUA recommends against screening in men under age 40.  Such blanket recommendations can increase the risk of younger men being overlooked and potentially resulting in worse disease later in life. Men under 40 need to be educated about prostate cancer and given a clear understanding of their individual risk factors.   Obesity/excess weight, a family history of prostate cancer, and African American race are the driving risk factors of this disease. • The AUA recommends against routine screening in men of average risk aged 40 to 54 years old.  Early diagnosis and treatment are the two most important factors to successfully eliminating prostate cancer. • The AUA strongly recommends careful consideration of the pros and cons of screening for men between the ages of 55 and 69.  The risk of prostate cancer increases significantly by age 65; so it’s wise for men in this age bracket to be screened. These men have the greatest opportunity for early detection and treatment to eliminate their prostate cancer with optimal quality of life. • The AUA suggests screening for prostate cancer every two years rather than annually. PSA is not a perfect test.  Prostate cancer can be an indolent cancer, taking many years to decades before it causes problems or it can behave in a highly aggressive manner. PSA is not able to differentiate these two cases. However, by tracking PSA velocity and density we can more accurately predict one’s risk of cancer. • The AUA recommends against PSA screening in men over age 70 with a life expectancy less than 10-15 years.  Now that such a large percentage of Americans live well into their 80s, prostate cancer screening should be part of overall wellness monitoring for these men. Prostate cancer remains the second leading cause of cancer death in men, killing approximately 34,000 men each year.  Since the widespread adoption of PSA screening in the early 90s, there has been a 39 percent reduction in prostate cancer mortality rates; so there is no doubt that PSA screening is successful – when used correctly.   Speak with your doctor about your individual risk factors for prostate cancer and your treatment goals.  Through comprehensive education about prostate cancer testing, diagnosis, and treatment options, American men can make well-informed decisions about what’s best for them. Dr. David B. Samadi is the Vice Chairman of the Department of Urology and Chief of Robotics and Minimally Invasive Surgery at the Mount Sinai School of Medicine in New York City. He is a board-certified urologist, specializing in the diagnosis and treatment of urological disease, with a focus on robotic prostate cancer treatments. To learn more please visit his websites RoboticOncology.com and SMART-surgery.com. Find Dr. Samadi on Facebook.Dr. David B. Samadi is the Vice Chairman of the Department of Urology and Chief of Robotics and Minimally Invasive Surgery at the Mount Sinai School of Medicine in New York City. He is a board-certified urologist, specializing in the diagnosis and treatment of urological disease, with a focus on robotic prostate cancer treatments. To learn more please visit his websites RoboticOncology.com and SMART-surgery.com. Find Dr. Samadi on Facebook.source : http://www.foxnews.com/health/2013/05/17/what-need-to-know-about-new-psa-screening-guidelines/

Study brings greater understanding of tumor growth mechanism

The study is published in Brain: A Journal of Neurology. Tumour suppressors exist in cells to prevent abnormal cell division in our bodies. The loss of a tumour suppressor called Merlin leads to tumours in many cell types within our nervous systems. There are two copies of a tumour suppressor, one on each chromosome that we inherit from our parents…

Students visiting PSU come home with bedbug bites

Some of 40 chaperones and students visiting Penn State's main campus say they came home with bedbug bites. The school says bedbugs were reported in the Curtin Hall dormitory. Three rooms were treated, and all of the residence hall's rooms are being checked. A university spokeswoman says a pest control service used a heat treatment to get rid of the bugs. Several Pittsburgh high school students staying in the dorm for the Junior Academy of Science State Meet science competition over the weekend say they came home with bedbug bites. Parents say the students were sent home with their luggage and clothes wrapped in garbage bags and information on how to prevent the bugs from spreading to their homes. The students say the rooms were dirty when they arrived.source : http://www.foxnews.com/health/2013/05/17/students-visiting-psu-come-home-with-bedbug-bites/

Organic industry clout grows with consumer demand

The organic food industry is gaining clout on Capitol Hill, prompted by rising consumer demand and its entry into traditional farm states. But that isn't going over well with everyone in Congress. Tensions between conventional and organic agriculture boiled over this week during a late-night House Agriculture Committee debate on a sweeping farm bill that has for decades propped up traditional crops and largely ignored organics. When Rep. Kurt Schrader, D-Ore., a former organic farmer, offered an amendment to make it easier for organic companies to organize industrywide promotional campaigns, there was swift backlash from some farm-state Republicans, with one member saying he didn't want to see the industry get a free ride and another complaining about organics' “continued assault on agriculture.” “That's one of the things that has caught me and raises my concerns, is that industry's lack of respect for traditional agriculture,” said Rep. Austin Scott, R-Ga., referring to some organic companies' efforts to reduce the number of genetically modified crops in the marketplace. At the same time, Scott acknowledged that he and his wife buy organic foods. Growing consumer interest in organics has proved tough for some Republicans on the committee to ignore. Eight Republicans, most of them newer members of the committee, joined with all of the panel's Democrats in supporting the amendment, which was adopted 29-17. Rep. Vicky Hartzler, a Missouri Republican who owns a farm equipment business and a corn and soybean farm, said she supported the amendment not only because helping organics is good for agriculture but because many of her constituents eat organic foods. “Organics are a niche market in agriculture with a growing market share, so it makes sense for me to allow farmers to invest some of their own funds to promote their products,” she said. The amendment would allow the organic industry to organize and pay for a unified industry promotional campaign called a “checkoff” that is facilitated by the Agriculture Department but is no cost to the government. These promotional programs have traditionally been limited to individual commodities or crops, producing familiar campaigns like “Got Milk?” and “Beef: It's What's for Dinner.” The amendment would not set up such a program for organics, but it would allow USDA to approve an organic promotional campaign if the industry decided it wanted one. Laura Batcha of the Organic Trade Association says one reason the industry would approve a campaign is that many organic producers are concerned that consumers don't understand that products labeled “natural” aren't necessarily organic, which requires certification. The organic industry has exploded in the last decade, with $35 billion in sales and 10 percent growth just last year. There are more than 17,000 certified organic businesses in the country. Producers of organic crops and conventional crops have long been at odds, as organic products have grabbed market share - more than 4 percent of food and beverage sales in 2011 - and the industry has advertised organic foods as healthier than other foods. Organic products are required to be certified by the USDA and are grown without pesticides and genetically modified ingredients, mainstays of traditional agriculture. Government-managed promotional checkoff programs like the one that would be allowed under the amendment are required to be positive and not disparage other products, and some lawmakers seemed wary that such a campaign would be possible. “How do I present organic pork without disparaging non-organic pork?” asked House Agriculture Chairman Frank Lucas, R-Okla., who opposed the amendment. Mike Conaway, R-Texas, took issue with part of the amendment that would allow the organic producers to opt out of other commodity campaigns, an option that isn't given to conventional producers. “Looks to me like they have a free ride on this thing,” Conaway said, in an at times angry exchange with Schrader. Despite the rancor, the chances that the amendment will become law are good, as the Senate Agriculture Committee added the same amendment to its version of the farm bill. Schrader told his colleagues that embracing organics is essential to appealing to consumers in a time when big farms are often demonized by popular culture. He said that many young people are coming back to farms because of nontraditional agriculture. “American agriculture is under siege,” he said. “Urban folks do not understand where their food and fiber comes from. ... The point here is to hopefully position American agriculture where we're not always trying to catch up to what the American consumer wants.”source : http://www.foxnews.com/health/2013/05/17/organic-industry-clout-grows-with-consumer-demand/

Experts devise new embryo selection method to boost IVF success

British fertility experts have devised a new IVF technique that takes thousands of snapshots of a developing embryo that they say can help doctors pick those most likely to implant successfully and develop into healthy babies. At a briefing in London before publishing their results, the researchers said they are already using the technique to select “low risk” embryos that are the least likely to have chromosomal abnormalities that could hamper their development. In their study, published in the journal Reproductive BioMedicine Online, the team's chances of producing a successful live birth after in-vitro fertilization (IVF) were increased by 56 percent using the new technique compared to the standard method of selecting embryos that look best through a microscope. “In the 35 years I have been in this field, this is probably the most exciting and significant development that can be of value to all patients seeking IVF,” said Simon Fishel, a leading fertility doctor and director at the IVF clinic operator CARE Fertility where the technique is being developed. Independent scientists not involved in the work welcomed it as a significant advance but said full randomized controlled trials - the gold standard in medicine - should be conducted before it is adopted as mainstream practice. “This paper is interesting because we really do need to make advances in selecting the best embryos created during IVF,” said Allan Pacey of Sheffield University, chair of the British Fertility Society. “The idea of monitoring embryo development more closely is being used increasingly in clinics around the world and so it is good to see the science involved submitted to peer review and publication,” he added. “All too often, developments in IVF are trumpeted as advances when they remain unproven.” Experts say that today, as many as 1 to 2 percent of babies in the Western world are conceived through IVF. The standard methods of selecting embryos are based largely on what they look like through a microscope, and many IVF cycles fail because the embryo chosen and transferred to the womb fails to develop. The scientists who led this study said that using time-lapse images, they had found that developmental delays in the embryo at crucial stages are good indicators of likely chromosomal abnormalities that could result in a failed pregnancy. Viewing far more images “In conventional IVF laboratories, embryo development will be checked up to six times over a 5-day period,” said Alison Campbell, Care Fertility's embryology director and the lead researcher on the study being published. “With time-lapse we have the ability to view more than 5,000 images over the same time period to observe and measure more closely each stage of division and growth.” Using this new knowledge, the team developed what they call morphokinetic algorithms to predict success (MAPS). By applying these MAPS to the selection of embryos, they predict they could reach a live birth rate for patients undergoing IVF of 78 percent - about three times the national average. Fishel, whose CARE Fertility clinics are Britain's largest independent provider of assisted conception cycles, with around 3,500 a year, said he is charging around 750 pounds ($1,100) for IVF using the MAPS technique - compared to several thousand pounds for a standard IVF cycle. But Sue Avery, head of the Women's Fertility Centre in Birmingham, said it was too soon for all clinics to adopt it. “Until the new technique is compared to current practice we cannot know whether different embryos are being chosen,” she said. “The IVF community needs a prospective randomized controlled trial to prove that the new approach delivers better results before it can be recommended to patients.”source : http://www.foxnews.com/health/2013/05/17/experts-devise-new-embryo-selection-method-to-boost-ivf-success/

Combined supplements no better for cholesterol

The cholesterol-lowering agent red yeast rice, an alternative treatment method for patients that can't tolerate statin drugs, doesn't work any better when a plant-derived compound called sterol is added to it, according to a new study.  “I expected to see a synergistic effect with red yeast rice, and I was shocked to see no effects whatsoever,” the study's lead author Dr. David Becker said. Statin drugs like Lipitor are the first-line option for lowering low-density lipoprotein (LDL) levels, or “bad cholesterol,” for patients at risk for heart disease, said Becker, a cardiologist with Temple Health Systems in Philadelphia. But while 15 million Americans take statin drugs, according to IMS Health, “10 to 20 percent of people can't tolerate statins and stop them,” said Becker, because of bothersome side effects, like muscle pain. Some of those people turn to red yeast rice, which is made by culturing yeast on the grain, and contains a statin-like compound that slows the body from making its own cholesterol. Red yeast rice supplements usually cost about $20 for a bottle of between 100 and 200 600-milligram tablets. Previous studies found that phytosterols, plant-derived steroids found in vegetable oil, lower LDL levels when used alone. Outside of dietary sources like margarine, phytosterol supplements are available in drug stores for about $20 for 200 900-milligram tablets. The study included 220 people with high LDL, averaging around 150 milligrams per deciliter, who had discontinued or declined statins prescribed by their doctor. (For people without heart disease risk factors, national U.S. guidelines recommend levels below 130.) They all took 1,800 milligrams of red yeast rice twice per day. Half of the group also took two 450-milligram tablets of phytosterols twice daily, while others took a placebo, for one year. Half of the participants attended meetings with doctors, dietitians and exercise physiologists for three months and was told to exercise and eat a Mediterranean diet for the rest of the year. The other half did not have special diet or exercise instructions. There was no difference in LDL cholesterol between the phytosterol or placebo groups at three months, six months or one year, according to the study published in the American Heart Journal. “There was absolutely no effect of phytosterols in any manner across the board,” Becker said. Though the diet and exercise group members seemed to have a head start at lowering their LDL, at the end of the study both groups had arrived at the same average of about 110 milligrams per deciliter. SEVERAL LIMITATIONS The trial had several limitations, according to Dr. Jeffrey Shanes, a cardiologist at Loyola-Gottlieb Memorial and Elmhurst Memorial Hospitals in Melrose Park, Illinois. About 30 percent of study participants dropped out of the trial after being screened and put in a treatment group, Shanes, who was not involved in the study, said. The statin-like compound in red yeast rice can cause the same muscle pain as synthetic statins for some patients, he said. Red yeast rice contains some sterols of its own, so it's possible that adding more sterols didn't appear to lower LDL any further because they were already in play, Shanes said. Becker would recommend diet and exercise before red yeast rice, he said. Batches subject to poor quality control may contain a potentially fatal liver-damaging byproduct of yeast fermentation, for example. And it may also increase the risk of muscle injury when combined with other cholesterol drugs. “Under no circumstances should people be going to Walgreens and getting red yeast rice because of the potential drug interactions, because every batch is different,” Shanes said.source : http://www.foxnews.com/health/2013/05/17/combined-supplements-no-better-for-cholesterol/