Researchers behind a study at The University of Texas MD Anderson Cancer Center believe they may have found a molecule-based approach to halting 3q26.2’s destructive nature. By manipulating a non-coding microRNA (miRNA) known as miR569 that is part of the amplicon, scientists were able to increase cell death in vitro and in vivo…
According to the study published in Preventing Chronic Disease, a publication of the Centers for Disease Control and Prevention, HPV vaccination rates are low among Puerto Rican women. Fifty one percent of Puerto Rican girls aged 11 to 18 have started the 3-step vaccination process and only 21 percent have completed the series. “Our study is the first to provide insight into common psychosocial barriers affecting HPV vaccination in Puerto Rico,” said Mar�a E…
Their findings will be reported online Dec. 6 in the New England Journal of Medicine, and presented on Dec. …
The study suggests that doctors and patients may find it difficult to withhold treatment previously considered standard of care, even in the setting of high quality data demonstrating that the advantages are small. “The onus is on physicians to critically analyze data to shape our treatment recommendations for patients, weighing the potential toxicities of treatment against clinical benefit,” said Rachel Blitzblau, M.D., Ph.D., the Butler Harris Assistant Professor of Radiation Oncology at Duke University Medical Center. Blitzblau was the senior author of a study published online Dec. 8, 2014, in the journal Cancer. …
The results provide some of the most dramatic evidence to date of the potential of therapies that increase the ability of the immune system to kill cancer cells. While clinical trials of such immunotherapies in other cancers have shown them to be highly effective in a subgroup of patients, the new study stands out because nearly all patients benefited from the treatment…
The team identified a critical pathway of molecular signals which throw a lifeline to cancer cells, enabling them to survive even though they contain vast DNA errors which would usually trigger cell death. The PKCƐ signal pathway, which is used by cancer cells but rarely by normal cells, could be important in targeting some cancer cells as they rely on this pathway to survive…
The research, which has shown promise in clinical samples, has been published in the scientific journal, Cell Death and Disease. The group of scientists coordinated by Dr Salvador Macip from the Mechanisms of Cancer and aging Lab and the Department of Biochemistry of the University of Leicester carried out the study to find new ways of identifying old cells in the body…
The question becomes who is invading whom — do cancer cells invade the basement membrane or do some fibroblasts help invading cancers? Researchers at the Institut Curie in Paris now say that they have evidence of a coordinated attack on the basement membrane by cancer cells in situ and CAF cells in the extracellular matrix that begins long before the actual translocation of cancer cells. …
The new report by Cancer Research UK and the National Cancer Intelligence Network reveals the difference in rates of surgery across 21 different cancer types. While many factors might be at play — frailty, suffering more than one illness, being diagnosed at a late stage, patients choosing not to undergo surgery — these statistics paint a worrying picture. Younger cancer patients were more likely to have surgery for 19 cancer types, with the largest differences between age groups seen in kidney and ovarian cancers. …
Published online Dec. …