"While it is established that tobacco smoke is a risk factor for nasopharyngeal carcinoma [the most common cancer arising from the upper part of the throat behind the nose and near the base of skull], its role in influencing survival of patients with established cancers is not known," said Fang-Yun Xie, M.D., professor in the Department of Radiation Oncology at the Sun Yat-sen University Cancer Center in Guangzhou, China. …
The findings are important because lowering the cell cycle progression (CCP) score may help prevent prostate cancers from becoming more aggressive, said study lead author William Aronson, a clinical professor of urology at UCLA and chief of urologic oncology at the West Los Angeles Veterans Affairs Medical Center. "We found that CCP scores were significantly lower in the prostate cancer in men who consumed the low-fat fish oil diet as compare to men who followed a higher fat Western diet," Aronson said…
Now, an ASU research team led by Biodesign Institute executive director Dr. Ray DuBois, M.D., PhD, has shown that a key genetic culprit, called CXCR2, is implicated in the tumor formation, growth and progression in a mouse model of colon cancer. …
Results from the research, which looked retrospectively at the treatment of women diagnosed with cervical cancer during a two year period, showed 18% of cervical cancer patients in the East African country died within two years of a diagnosis. Dr Ian Hampson, from The University of Manchester’s Institute of Cancer Sciences who oversaw the research, said the findings, published in PLOS One this week, add further weight to the call to spend more on cancer screening and prevention in Kenya…
"The gold standard of diagnosis is currently colonoscopy," says corresponding author of the study, Dr. Rima Rozen, a geneticist from the Departments of Human Genetics and Pediatrics at The Montreal Children’s Hospital of the MUHC and McGill University. "This is an invasive procedure, where the physician looks for abnormal tissue or growths also known as polyps." Additionally, given surging demand for colonoscopies, this research may ultimately offer an alternative option for early diagnosis, paving the way for the reduction in wait time. According to Dr…
The study, to be published online Nov. …
The study appears online this week in the Early Edition of the Proceedings of the National Academy of Sciences. "Cancer cells behave in complex ways, and this work shows how such complexity can arise from the operation of a relatively simple decision-making circuit," said study co-author Eshel Ben-Jacob, a senior investigator at Rice’s Center for Theoretical Biological Physics (CTBP) and adjunct professor of biochemistry and cell biology at Rice. "By stripping away the complexity and starting with first principles, we get a glimpse of the ‘logic of cancer’ — the driver of the disease’s decision to spread." In the PNAS study, Ben-Jacob and CTBP colleagues José Onuchic, Herbert Levine, Mingyang Lu and Mohit Kumar Jolly describe a new theoretical framework that allowed them to model the behavior of microRNAs in decision-making circuits…
The study, carried out by researchers at the UCL Department of Women’s Cancer, found that abnormal levels of female hormones in the bloodstream could be the answer. The findings have already led to more research into novel ways of preventing cancers in women at risk. According to the results of the study, women with BRCA1 or BRCA2 mutations are exposed to different levels of the female hormones oestradiol and progesterone, which are already known to be risk-factors for breast and ovarian cancer. …
Prof Boniol, Research Director at the International Prevention Research Institute (iPRI) and Professor at the Strathclyde Institute for Global Public Health at iPRI, Lyon, France, will tell the congress that the total harm men experience in terms of impotence and incontinence, and the side-effects from prostate cancer treatments, severely affects their quality of life, and should further discourage the use of PSA testing for prostate cancer screening. Prof Boniol will say: "The test measures PSA protein levels, which are produced by the prostate gland, in a man’s blood, and may help detect early cancer…
It was published early online October 4, 2013 in Cancer Epidemiology, Biomarkers, and Prevention. …