Tag Archives: modern

New breast cancer test links immune ‘hotspots’ to better survival

Researchers used statistical software previously used in criminology studies of crime hotspots to track the extent to which the immune system was homing in and attacking breast cancer cells. The test, described in the journal Modern Pathology, could assess whether a woman’s immune system is holding a cancer at bay — and pick out those who will need intensive treatment to combat their more aggressive disease. Scientists at The Institute of Cancer Research, London, analysed tumour samples from 245 women with a type of breast cancer called oestrogen receptor negative (ER negative), which is particularly hard to treat. …

Patients treated with radiation therapy who have tumors in left breast have comparable overall survival to those with tumors in right breast –…

Studies have shown that breast cancer patients treated with radiation therapy have improved local-regional recurrence, and breast cancer-specific survival after breast-conserving surgery and overall survival (OS) after mastectomy. Long-term follow-up of historic radiation therapy trials for breast cancer has demonstrated a potential increase in cardiac mortality. However, these studies used earlier modes of radiation therapy including Cobalt and orthovoltage radiotherapy, and did not employ CT-based planning, which allows for greater cardiac avoidance. Three recent studies suggest that cardiac mortality has not been greater for patients treated for left-sided breast cancer since the 1980s, when techniques allowing for greater cardiac avoidance became more commonplace[1-3]. …

Breast conserving therapy shows survival benefit compared to mastectomy in early-stage patients with hormone receptor positive disease — ScienceDaily

The study findings defy the conventional belief that the two treatment interventions offer equal survival, and show the need to revisit some standards of breast cancer practice in the modern era. The research was presented at the 2014 Breast Cancer Symposium by Catherine Parker, MD, formerly a fellow at MD Anderson, now at the University of Alabama Birmingham. In the 1980s, both US-based and international randomized clinical studies found that BCT and mastectomy offered women with early stage breast cancer equal survival benefit…

Breast conserving therapy shows survival benefit compared to mastectomy in early-stage patients with hormone receptor positive disease

The study findings defy the conventional belief that the two treatment interventions offer equal survival, and show the need to revisit some standards of breast cancer practice in the modern era. The research was presented at the 2014 Breast Cancer Symposium by Catherine Parker, MD, formerly a fellow at MD Anderson, now at the University of Alabama Birmingham. In the 1980s, both US-based and international randomized clinical studies found that BCT and mastectomy offered women with early stage breast cancer equal survival benefit…