Tag Archives: materials

Harnessing power of immune system for therapies against cancer

The new studies find high activity with investigative drugs for advanced melanoma, and show for the first time that ipilimumab, a treatment already approved for advanced melanoma, can substantially decrease the risk of melanoma recurrence in certain patients with earlier-stage disease. In addition, another small trial reports that a one-time, personalized immunotherapy treatment induces complete and long-lasting remissions in a small number of women with advanced cervical cancer — a disease with little to no effective treatment options. …

HPV testing: Benefit in primary screening

HPV testing is not reimbursed by SHI funds In screening for cervical cancer, the German statutory health insurance (SHI) funds currently offer an annual cytologic examination of mucosal cells from a smear taken from the neck of the womb (cervix). This test is called a Pap smear. Since it became known that infection with HPV is the main risk factor for developing cervical cancer, experts have been discussing whether HPV testing is also a suitable screening method or is even superior to a cytologic test…

Bonuses for doctors do little to improve cancer screening in Ontario

The study, published today in Annals of Family Medicine, tracked screening rates for cervical, breast and colorectal cancer in Ontario each year between 2000 and 2010. Researchers found no significant changes in breast and cervical cancer screening rates after bonuses were introduced for doctors in 2006. …

Even mild traumatic brain injury may cause brain damage

For the study, 44 people with a mild traumatic brain injury and nine people with a moderate traumatic brain injury were compared to 33 people with no brain injury. All of the participants took tests of their thinking and memory skills. At the same time, they had diffusion tensor imaging scans, a type of MRI scan that is more sensitive than traditional MRI for detecting damage to brain cells and helps map fiber tracts that connect brain regions. The people with brain injuries had their scans an average of six days after the injury. …

Rare form of tongue cancer suggests screening vigilance

A 65-year-old male patient with a history of chronic alcoholism complained of an odd, painless white growth over his tongue. Doctors at the Government Medical College in Latur, India were intrigued when they identified the hard white growth as a rare case of spindle cell carcinoma. Spindle cell carcinoma is an aggressive variant of squamous cell carcinoma. These tumors get their name from their distinctive spindle-shaped cells, readily detectable by immunohistochemistry…

New metastasis-suppressor gene identified by cancer researchers — ScienceDaily

Activation of the PI3K/AKT signal pathway is a known driver of the progression of prostate cancer to the castrate-resistant stage, the most lethal form of prostate cancer. Using a genome-wide genetic screen, Dr. Gelman and colleagues identified a previously unknown metastasis suppressor — the FOXO4 protein, which belongs to a family of genes that are produced by all human cells. …

Presence of uterine cancers at time of hysterectomy studied using morcellation

Despite the commercial availability of electric power morcellators for 2 decades, accurate estimates of the prevalence of malignancy at the time of electric power morcellation (in this study referred to as morcellation) have been lacking, according to background information in the article. Jason D. Wright, M.D., of the Columbia University College of Physicians and Surgeons, New York, and colleagues used a large insurance database to investigate the prevalence of underlying cancer in women who underwent uterine morcellation. …