Research suggests that the permanent pin prick marks made on the skin of women having radiotherapy reminds them of their diagnosis for years to come, reducing body confidence and self-esteem. It’s also more difficult to spot these tattoos in dark-skinned women, potentially leading to inconsistencies in the area being treated…
“Oncology is an exceptionally rewarding career, but it can be demanding and stressful at times,” said Dr Susana Banerjee, lead author of the study and a consultant medical oncologist at The Royal Marsden NHS Trust in London, UK. “Oncologists make complex decisions about cancer management, supervise the use of toxic therapies, work long hours, and continually face patients suffering and dying,” she said…
The drug, Verdinexor (KPT-335), works by preventing powerful tumor suppressing proteins from leaving the nucleus of cells, an exodus which allows cancer to grow unchecked. It’s the first new therapeutic option for dog lymphoma in more than two decades, potentially offering vets another alternative for treating the disease, which is the most common form of canine cancer…
In a survey of around 2,200 women, Cancer Research UK scientists at University College London (UCL) found that 64 per cent felt they fully understood the information given about overdiagnosis — the chance that screening will pick up cancers that would never have gone on to cause any harm — by the National breast screening programme. Information about overdiagnosis has only been included in the NHS breast screening invitation leaflets since late 2013, meaning that overdiagnosis is likely to be a new concept for many people. But despite uncertainty over the information they were given, intentions to attend breast screening remained high, with only seven per cent of women saying they would be less likely to attend screening after receiving the overdiagnosis information. …
In a survey of around 2,200 women, Cancer Research UK scientists at University College London (UCL) found that 64 per cent felt they fully understood the information given about overdiagnosis — the chance that screening will pick up cancers that would never have gone on to cause any harm — by the National breast screening programme. Information about overdiagnosis has only been included in the NHS breast screening invitation leaflets since late 2013, meaning that overdiagnosis is likely to be a new concept for many people. But despite uncertainty over the information they were given, intentions to attend breast screening remained high, with only seven per cent of women saying they would be less likely to attend screening after receiving the overdiagnosis information…
The findings, set out in the Journal of the National Cancer Institute, are based on the experience of more than 2,000 young women in England and Wales treated for the cancer over a period of more than 40 years. Previous research has suggested that women with Hodgkin lymphoma who receive certain types of chemotherapy or radiotherapy are at increased risk of going through the menopause early — but there was insufficient information to provide patients with detailed advice. But the new study, led by scientists at The Institute of Cancer Research, London, provides precise estimates of risk for women depending on which treatment types and doses they received and at what age — allowing doctors to give them detailed advice about their risks of future infertility…
The study was conducted amongst children with Down’s syndrome — who are 20-50 times more prone to childhood leukemias than other children — and involved analysing the DNA sequence of patients at different stages of leukemia. The researchers uncovered that two key genes (called RAS and JAK) can mutate to turn normal blood cells into cancer cells. However, these two genes never mutate together, as one seems to exclude the other. This discovery means we can begin to identify which of the two genes are mutated in patients, and therefore more effectively target their cancer in lower doses (reducing toxicity for the patient) with less side-effects…
The study demonstrates that sunscreen, even with a sun protection factor (SPF) 50, may not fully protect against the development of melanoma. According to the researcher at the UMH Berta López Sánchez-Laorden, sunscreen protects against immediate radiation damage including sunburn, but the radiation can still penetrate and damage the DNA of cells and cause cancer. Through the use of genetically modified mice particularly susceptible to melanoma, the researcher discovered that ultraviolet light causes mutations in the DNA of melanocytes in a gene called p53. …
Scientists discovered that cells can change into an invasive, liquid-like state to readily navigate the narrow channels in our body. …
source : http://www.sciencedaily.com/releases/2014/05/140513190535.htm