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Vitamin D supplements could help Crohn’s patients fight fatigue, improve quality of life

Scientists have long known that Crohn’s patients – even when they are in remission – suffer from fatigue and low quality of life. So when Tara Raftery, a research dietitian at Trinity College in Dublin, Ireland, who works specifically on Crohn's disease, saw emerging evidence suggesting a lack of vitamin D may alter muscle function and strength she decided to set up a study investigating the possible effects of vitamin D on fatigue and quality of life in Crohn’s patients. Crohn’s disease is an inflammatory condition  with no known cure and often causes diarrhea, abdominal pain, mouth sores and joint pain. Patients often feel extremely fatigued – either from the extensive medicines they have to take or from the disease itself. “Some research has suggested that vitamin D supplementation might influence muscle strength and quality of life,” Raftery told FoxNews.com. “But this was yet to be shown in Crohn’s disease.” Raftery said she and her doctorate supervisor, Maria O’Sullivan, performed a three-month study, where half of the participants – all Crohn’s patients who were in remission –  were given vitamin D supplements and the other half were given a placebo. “So at the start of the study, we measured their baseline vitamin D levels,” Raftery said. “We also measured fatigue and quality of life by using validated questionnaires, and we measured hand-grip strength – this gave us a proxy measure of their muscle strength.” At the end of three months, the researchers repeated those measures. “What we found, was in the participants who received the vitamin D supplements (of 2,000 International Units per day), their hand-grip strength was significantly stronger than those who took the placebo,” Raftery said. “We measured both the dominant and non-dominant hand grip strength at baseline. After three months, those who had received the vitamin D supplement had significantly stronger hand grip, in both hands, compared to those who were randomized to the placebo pill.” Raftery said they also found the patients who had vitamin D levels of above 30 ng/ml had a significantly higher quality of life compared to those patients who had less than that and those patients taking the placebo. “In terms of fatigue, what we found was that when the levels were 30ng/ml  or more, the patients reported significantly less physical fatigue, as well as mental and general fatigue,” Raftery said. Raftery said these findings are the first to suggest the potential benefits of vitamin D supplementation in Crohn’s patients to improve muscle function, fatigue and quality of life. While more studies need to be done, researchers are hopeful. Raftery is currently conducting a larger study – containing more participants studied over a one-year period - to confirm her initial findings. “What I would recommend, is that patients with Crohn's disease discuss supplementation with their doctor and also have their levels rechecked about three months after supplementation begins,” Raftery said. “Vitamin D supplementation is safe for most people, but not everyone . . . mega-doses should be avoided and many countries have set upper limits of 2,000-4,000 International Units a day for adults.” Raftery will present her findings at Digestive Disease Week in Orlando during the week of May 20.source : http://www.foxnews.com/health/2013/05/20/vitamin-d-supplements-could-help-crohns-patients-fight-fatigue-improve-quality/

How not to gain too much pregnancy weight

For many women, the extra calories that are vital for a healthy pregnancy often become a green light to indulge and give into cravings. In fact, more than 30 percent of women who have a normal weight before becoming pregnant gain more than the recommended amount during pregnancy, according to the Centers of Disease Control and Prevention’s Pregnancy Risk Assessment Monitoring System. If you’re overweight or obese before getting pregnant, or you gain too much weight during pregnancy, you and your baby’s health could be compromised. For starters, there’s an increased risk of high blood pressure, gestational diabetes and preeclampsia. There’s also a greater chance that you could have a miscarriage, a stillborn baby, deliver early or be required to have a cesarean section. Your baby could also develop birth defects and detecting them with an ultrasound can be tricky if you’re obese, according to Dr. Alyssa Dweck, a board-certified obstetrician and gynecologist and co-author of V is for Vagina. During labor and delivery, there’s also a higher chance for blood clots, C-section infection, and difficulty administering anesthesia. You might also have a larger baby, and studies show overweight women also have problems breastfeeding. Plus, losing weight after delivery could be tough too. Several rat studies also indicate that babies born to overweight moms might actually have permanent changes in their brain structures and genetic preferences that could put them at risk for cardiovascular disease, high blood pressure, and diabetes. “It is possible that we’re creating a generation of kids who are more likely to be obese, and as they grow up and have children, it creates more and more of a genetic problem,” said Melinda Johnson, a registered dietitian and spokesperson for the Academy of Nutrition and Dietetics. Babies born to overweight mothers are also more likely to be overweight themselves, but it’s not clear if it’s because they have the same eating habits as their moms or if it’s just plain genetics, according to Johnson. Regardless, “pregnancy is a great time for future mothers to start learning better habits, because we definitely know those habits play a huge role in the health of their children,” she said. If you’re planning to get pregnant or you already are, find out what you can do to have a healthy weight.   Know the guidelines Even if you’re already overweight, weight loss should never be your goal during pregnancy, according to Dweck.  Instead, follow the Institute of Medicine’s guidelines for pregnancy weight gain, which are based on your body mass index (BMI). So if your BMI is normal, aim to gain 25 to 35 pounds; if you’re overweight stay within 15 to 25 pounds, and if you’re obese, 11 to 20 pounds. Take your vitamins To make sure you’re getting the right amount of nutrients, look for a prenatal vitamin with 1 milligram of folic acid, iron and docosahexaenoic acid (DHA). A good prenatal should also have 1200 milligrams of calcium and 600 to 1,000 milligrams of vitamin D. Eat a balanced diet It’s important to eat regular meals throughout the day to keep your blood sugar steady and your energy levels up. Johnson recommended eating every two to four hours depending on how hungry you are.  It’s OK to give into your cravings, but try to put the focus on eating lots of fruits and vegetables, whole grains, lean proteins, and low-fat dairy. Instead of eating foods loaded with saturated fats, opt for those with heart healthy fats like salmon, avocado, nuts and seeds. Drink plenty of water and nix soda, juice and sugary drinks. “Those are empty calories; they’re never going to make you feel full,” Dweck said. Talk to an expert If you’re worried about your weight or your diet, talk to your doctor or a registered dietitian about nutrition and exercise – ideally before you get pregnant.  Pregnancy is not the time to start an exercise program, Dweck said. Don’t look at the scale Is the number on the scale creeping higher every week despite your best efforts? Don’t fret, said Johnson, who noted that your weight doesn’t matter if you’re making healthy choices, paying attention to portion sizes and exercising. “If women follow that advice, they can save themselves a lot of stress,” she said.Julie Revelant is a freelance writer specializing in parenting, health, food and women's issues and a mom. Learn more about Julie at revelantwriting.com.source : http://www.foxnews.com/health/2013/05/19/how-not-to-gain-too-much-pregnancy-weight/

Victims claim Marines failed to safeguard water supply

CAMP LEJEUNE, N.C. – & A simple test could have alerted officials that the drinking water at Camp Lejeune was contaminated, long before authorities determined that as many as a million Marines and their families were exposed to a witch's brew of cancer-causing chemicals. But no one responsible for the lab at the base can recall that the procedure -- mandated by the Navy -- was ever conducted. The U.S. Marine Corps maintains that the carbon chloroform extract (CCE) test would not have uncovered the carcinogens that fouled the southeastern North Carolina base's water system from at least the mid-1950s until wells were capped in the mid-1980s. But experts say even this “relatively primitive” test -- required by Navy health directives as early as 1963 -- would have told officials that something was terribly wrong beneath Lejeune's sandy soil. A just-released study from the federal Agency for Toxic Substances and Disease Registry cited a February 1985 level for trichloroethylene of 18,900 parts per billion in one Lejeune drinking water well -- nearly 4,000 times today's maximum allowed limit of 5 ppb. Given those kinds of numbers, environmental engineer Marco Kaltofen said even a testing method as inadequate as CCE should have raised some red flags with a “careful analyst.” “That's knock-your-socks-off level -- even back then,” said Kaltofen, who worked on the infamous Love Canal case in upstate New York, where drums of buried chemical waste leaked toxins into a local water system. “You could have smelled it.” Biochemist Michael Hargett agrees that CCE, while imperfect, would have been enough to prompt more specific testing in what is now recognized as the worst documented case of drinking-water contamination in the nation's history. “I consider it disingenuous of the Corps to say, `Well, it wouldn't have meant anything,”' said Hargett, co-owner of the private lab that tried to sound the alarm about the contamination in 1982. “The levels of chlorinated solvent that we discovered ... they would have gotten something that said, `Whoops. I've got a problem.' They didn't do that.” Trichloroethylene (TCE), tetrachloroethylene (PCE), benzene and other toxic chemicals leeched into ground water from a poorly maintained fuel depot and indiscriminate dumping on the base, as well as from an off-base dry cleaner. Nearly three decades after the first drinking-water wells were closed, victims are still awaiting a final federal health assessment -- the original 1997 report having been withdrawn because faulty or incomplete data. Results of a long-delayed study on birth defects and childhood cancers were only submitted for publication in late April. Many former Lejeune Marines and family members who lived there believe the Corps still has not come clean about the situation, and the question of whether these tests were conducted is emblematic of the depth of that mistrust. Marine Corps officials have repeatedly said that federal environmental regulations for these cancer-causing chemicals were not finalized under the Safe Drinking Water Act until 1989 -- about four years after the contaminated wells had been identified and taken out of service. But victims who have scoured decades-old documents say the military's own health standards should have raised red flags long before. In 1963, the Navy's Bureau of Medicine and Surgery issued “The Manual of Naval Preventive Medicine.” Chapter 5 is titled “Water Supply Ashore.” “The water supply should be obtained from the most desirable sources which is feasible, and effort should be made to prevent or control pollution of the source,” it reads. At the time, the Defense Department adopted water quality standards set by the U.S. Public Health Service. To measure that quality, the Navy manual identified CCE “as a technically practical procedure which will afford a large measure of protection against the presence of undetected toxic materials in finished drinking water.” Also referred to as the “oil and grease test,” CCE was intended to protect against an “unwarranted dosage of the water consumer with ill-defined chemicals,” according to the Navy manual. The CCE standard set in 1963 was 200 ppb. In 1972, the Navy further tightened it to no more than 150 ppb. In response to a request from The Associated Press, Capt. Kendra Motz said the Marines could produce no copies of CCE test results for Lejeune, despite searching for “many hours.” “Some documents that might be relevant to your question may no longer be maintained by the Marine Corps or the Department of the Navy in accordance with records management policies,” she wrote in an email. “The absence of records 50 years later does not necessarily mean action was not taken.” But the two men who oversaw the base lab told the AP they were not even familiar with the procedure. “A what?” asked Julian Wooten, who was head of the Lejeune environmental section during the 1970s, when asked if his staff had ever performed the CCE test. “I never saw anything, unless the (Navy's) preventive medicine people were doing some. I don't have any knowledge of that kind of operation or that kind of testing being done. Not back then.” “I have no knowledge of it,” said Danny Sharpe, who succeeded Wooten as section chief and was in charge when the first drinking water wells were shut down in the mid-1980s. “I don't remember that at all.” Wooten was an ecologist, and Sharpe's background is in forestry and soil conservation. But Elizabeth Betz, the supervisory chemist at Lejeune from 1979 to 1995, was also at a loss when asked about the CCE testing. “I do not remember any such test being requested nor do I remember seeing any such test results,” Betz, who later worked for the U.S. Environmental Protection Agency's national exposure branch at Research Triangle Park outside Raleigh, wrote in a recent e-mail. Hargett, the former co-owner of Grainger Laboratories in Raleigh, said he never saw any evidence that the base was testing and treating for anything beyond e coli and other bacteria. “That was a state regulation ... that they had to maintain a sanitary water supply,” he said. “And they did a good job at that.” Motz, the Marine spokeswoman, told the AP that the method called for in the manual would not have detected the toxins at issue in the Camp Lejeune case. “The CCE method includes a drying step and a distillation (evaporation) step where chloroform is completely evaporated,” she wrote in an email. These volatile organic compounds, “by their chemical nature, would evaporate readily as well,” she wrote. ATSDR contacted the EPA about the “utility” of such testing and concluded it would be of no value in detecting TCE, PCE, or benzene, Deputy Director Tom Sinks wrote in an email to members of a community assistance panel on Lejeune. “It is doubtful that the weight of their residue would be detectable when subjected to this method,” Sinks wrote. Kaltofen, a professor at Worcester Polytechnic Institute in Massachusetts, acknowledged that CCE is “a relatively primitive test.” But in addition to the water's odor, Kaltofen said, “there are some things that a careful analyst would easily have noticed.” Hargett agreed. “It would have prompted you to simply say, `Wow. There is something here. Let's do some additional work,”' he told the AP. Any “reputable chemist ... would have raised their hands to the person responsible and said, `Guys. You ought to look at this. There's more here.”' The Marines have said such high readings were merely spikes. But Kaltofen countered that, “You can't get that level even once without having a very serious problem ... It's the worst case.” In a recent interview, Wooten told the AP that he knew something was wrong with the water as early as the 1960s, when he worked in the maintenance department. “I was usually the first person in in the big building that we worked in,” he said. “And I'd cut the water on and let it run, just go and flush the commodes and cut the water on and let it run for several minutes before I'd attempt to make coffee.” Wooten said he made repeated budget requests for additional equipment and lab workers. But as Betz told a federal fact-finding group, “the lab was very low on the priority list at the base.” She said her group -- the Natural Resources and Environmental Affairs Department -- was “like the `red headed stepchild.”' Even a series of increasingly urgent reports from an Army lab at Fort McPherson, Ga., beginning in late 1980, failed to prompt any real action. “WATER HIGHLY CONTAMINATED WITH OTHER CHLORINATED HYDROCARBONS (SOLVENTS!)” cautioned one memo from the Army lab in early 1981. Because the base water system drew on a rotating basis from a number of different wells, subsequent tests showed no problems, and officials chalked these “interferences” up to flukes. One base employee told the fact-finding group that in 1980, “they simply did not have the money nor capacity” to test every drinking-water well on the base. “This type of money would have cost well over $100,000, and their entire operating budget was $100,000,” the employee said, according to a heavily redacted summary obtained by the AP from the Department of Justice through the Freedom of Information Act. “However, they did not do the well testing because they did not think they needed to.” So, from late 1980 through the summer of 1982, the former employee told investigators, “this issue simply laid there. No attempts were made to identify ground contamination” at Hadnot Point or Tarawa Terrace, where most of the enlisted men and their families lived. It wasn't until a letter from Grainger in August 1982 reported TCE levels of 1,400 ppb that any kind of widespread testing began. Though the EPA did not yet enforce a limit for TCE at the time, the chemical had long been known to cause serious health problems. “That is when the light bulb went off,” Sharpe told federal investigators in a 2004 interview, obtained by the AP. “That is when we connected the tests of the 1980, 1981, and 1982 time period where traces of solvents were detected to this finding.” Still, it was not until the final weeks of 1984 that the first wells were closed down. Between the receipt of that 1982 letter and the well closures, the employee told the fact-finding group, “they simply dropped the ball.” Each year of delay meant an additional 10,000 people may have been exposed, according to Marine estimates. Municipal utilities around the country were using far more sophisticated tests to detect much lower contaminate levels, said Kaltofen, while the people at Camp Lejeune were doing “the bare minimum. And it wasn't enough.” Last year, President Obama signed the Camp Lejeune Veterans and Family Act to provide medical care and screening for Marines and their families, but not civilians, exposed between 1957 and 1987 -- although preliminary results from water modeling suggest that date be pushed back at least another four years. The law covers 15 diseases or conditions, including female infertility, miscarriage, leukemia, multiple myeloma, as well as bladder, breast, esophageal, kidney and lung cancer. Jerry Ensminger, a former drill sergeant, blames the water for the leukemia that killed his 9-year-old daughter, Janey, in 1985. He and Michael Partain -- a Marine's son who is one of at least seven dozen men with Lejeune ties diagnosed with a rare form of breast cancer -- have scoured the records, and he thinks the Corps has yet to accept responsibility for its role in this tragedy. “If I hadn't dug in my heels,” Ensminger said, “this damned issue would have been dead and buried along with my child and everybody else's.”source : http://www.foxnews.com/health/2013/05/18/victims-claim-marines-failed-to-safeguard-water-supply/

Flesh-eating bacteria victim Aimee Copeland gets new bionic hands

Last summer, the nation was captivated by the story of Aimee Copeland, a University of West Georgia graduate student who lost both her hands and a leg to a terrible bout with flesh-eating bacteria, which she contracted during a zip-lining accident.   Now, a little over a year later, 25-year-old Copeland has been fitted with a new pair of prosthetic hands, which allow her to wipe down tables, fold towels and even straighten her hair, WLTX.com reported.   Thanks to a gift from Touch Bionics in Hilliard, Ohio, Copeland is the first woman in the world with bilateral upper limb amputations to be fitted with iLimb Ultra Prosthetic Hands.  According to the company, the prosthetic hands cost $100,000 each, but Touch Bionics gave them to Copeland free of charge, as she had run out of insurance to pay for them herself. To date, the iLimb hands are the most advanced and most versatile high-tech prosthetic hands available, and Copeland has spent the past week in Hilliard getting them fitted and learning how to use them.  In a video from WXIA of Columbus, Ohio, she was able to delicately pick up a single M&M. “It feels amazing, because you know, with the other arms I had, they really didn’t feel like an extension of my body,” Copeland told WXIA.  “This just feels very freeing; it’s more light-weight. And the hand actually… it seems like this could be my actual hand.” Copeland’s ordeal began in May 2012, when she was enjoying a trip kayaking down a creek with some of her friends in Carrollton, Ga.  But when Copeland stopped to ride on a homemade zip line along the water, the line snapped and cut a large gash in her left calf.   Doctors ultimately had to staple her leg up with 22 staples, and they told her to take pain medication.  But the pain did not subside, so a friend drove Copeland to the emergency room the next day, where doctors diagnosed her with necrotizing fasciitis – the infection and destruction of a layer of tissue right underneath the skin.  The bacteria had entered Copeland’s body through the gash she had received during the zip-lining accident.   Despite her initial odds of survival being “slim to none,” then 24-year-old Copeland eventually pulled through, but both her hands and her entire left leg had to be amputated in order to ensure her survival.  After two months in the hospital and two months of rehabilitation, Copeland returned to her renovated home in Snellville, Ga., where she began physical therapy. Click for more from WLTX.com.source : http://www.foxnews.com/health/2013/05/17/flesh-eating-bacteria-victim-aimee-copeland-gets-new-bionic-hands/

Up to 1 in 5 children suffer from a mental disorder, CDC says

Up to 20 percent of children in the United States suffer from a mental disorder, and the number of kids diagnosed with one has been rising for more than a decade, according to a report released on Thursday by the U.S. Center for Disease Control and Prevention. In the agency's first-ever study of mental disorders among children aged 3 to 17, researchers found childhood mental illnesses affect up to one in five kids and cost $247 billion per year in medical bills, special education and juvenile justice. Children with mental disorders - defined as “serious deviations from expected cognitive, social, and emotional development” - often have trouble learning in school, making friends, and building relationships later in life, the report said. They are more likely to have other chronic health problems, such as asthma and diabetes, and are at risk for developing mental illnesses as adults. “This is a deliberate effort by CDC to show mental health is a health issue. As with any health concern, the more attention we give to it, the better. It's parents becoming aware of the facts and talking to a healthcare provider about how their child is learning, behaving, and playing with other kids,” Dr. Ruth Perou, the lead author of the study, said in an interview. “What's concerning is the number of families affected by these issues. But we can do something about this. Mental health problems are diagnosable, treatable and people can recover and lead full healthy lives,” Perou added. The study cited data collected between 1994 and 2011 that showed the number of kids with mental disorders is growing. The study stopped short of concluding why, but suggested improvements in diagnoses as one possible explanation “Changes in estimated prevalence over time might be associated with an actual change in prevalence, changes in case definition, changes in the public perception of mental disorders, or improvements in diagnosis, which might be associated with changes in policies and access to health care,” the study said. Perou said more research was needed to determine the specific causes of mental disorders, and that greater awareness could lead to an uptick in diagnoses. A host of environmental factors, including chemical exposure and poverty, can also affect a child's mental health, she said. Lead, for example, is known to be “one of the biggest toxins to impact behavior and learning,” Perou said. Poor children are at a higher risk for developing certain conditions, according to the study. The most prevalent mental health diagnosis, as reported by parents, was Attention Deficit/Hyperactivity Disorder (ADHD), which affects 6.8 percent of children. Also common were behavioral conduct problems (3.5 percent), anxiety, which consists mostly of fears and phobias (3 percent), depression (2.1 percent) and autism spectrum disorders (1.1 percent). Many of these disorders occur together, the report said. Boys were found more likely to have most of the listed disorders except for depression and alcohol abuse, which affect more girls. The study also noted that suicide, which can be precipitated by an untreated mental illness, was the second leading cause of death (after accidents) among children 12 to 17 years old. The CDC report was based on multiple other studies that collected data and interviewed children and their guardians about their diagnoses, habits, behaviors and other factors.source : http://www.foxnews.com/health/2013/05/17/up-to-1-in-5-children-suffer-from-mental-disorder-cdc-says/

Brain makes call on which ear is used for cell phone

The study — to appear online in JAMA Otolaryngology-Head & Neck Surgery — shows a strong correlation between brain dominance and the ear used to listen to a cell phone. More than 70% of participants held their cell phone up to the ear on the same side as their dominant hand, the study finds. Left-brain dominant people — who account for about 95% of the population and have their speech and language center located on the left side of the brain — are more likely to use their right hand for writing and other everyday tasks. Likewise, the Henry Ford study reveals most left-brain dominant people also use the phone in their right ear, despite there being no perceived difference in their hearing in the left or right ear…

Vocal cord paralysis: Explaining Google CEO Larry Page’s rare condition

Earlier this week, Google CEO Larry Page finally revealed the reason behind his soft, hoarse-sounding voice: he suffers from a rare condition called vocal cord paralysis Though Page was able to speak on Wednesday at Google I/O, the company’s annual developer conference, he recently wrote on his Google Plus profile that he has struggled with vocal cord paralysis for the past 14 years. Page said he was first diagnosed with paralysis in his left vocal cord after a bad cold. However, his condition worsened last summer when his right vocal cord also became paralyzed. Experiencing paralysis in both vocal cords is extremely uncommon, according to Dr. Nicole Maronian, director of the Voice Center at University Hospitals Case Medical Center in Cleveland, Ohio, who did not treat Page for his condition. “Since I’ve been in practice, since 1998, it’s been one patient. Having it affect both vocal cords, it’s pretty rare,” Maronian told FoxNews.com. Normal vocal cords open and then close completely every time they are stimulated by the nerves. “They have to close in a tight line to get the kind of strong voice out that you and I have today,” Maronian said. But when vocal cords become paralyzed, they are not able to close completely, leaving a gap.  “If there’s a gap, air starts leaking through, and you start sounding breathy, softer,” Maronian explained.   In addition to hoarseness, patients with this paralysis can also experience shortness of breath due to air leaking through the gap between the vocal cords. “They often get a little bit high-pitched, trying to project or pitch the voice. They get short of breath because of all that air leaking out, or have trouble getting full sentences out because of the air leaking out,” Maronian said. Some patients even experience aspiration, when recently swallowed fluids leak through the space in between the vocal cords. Aspiration can lead to coughing symptoms or even “aspiration pneumonia, which has significant morbidity and mortality,” Maronian said. While the paralysis is typically thought to be caused by a viral infection, such as a cold, pneumonia or bronchitis, other factors may be to blame as well.   “Lots of things can affect the nerve: A virus, compression from a thyroid issue, other things like cancer, (or) surgeries where the nerve is ether stretched or pulled,” Maronian said. Page disclosed that he was also diagnosed with Hashimoto’s thyroiditis in 2008, an inflammation of the thyroid gland, which may or may not affect his vocal cord paralysis. “Sometimes the thyroid gets big which can compress the nerve and push on it. Usually though, the gland burns out and gets small and the nerve compression issue isn’t a piece of it anymore,” Maronian said. Recovery time for vocal cord paralysis can vary. Some patients rebound within months, while others take much longer to heal, Maronian noted. Depending on the needs of the patient, doctors can offer several treatment options for vocal cord paralysis. Patients can wait and see if the condition improves on its own, but many opt for vocal cord injections or surgical procedures to achieve faster relief and recovery. “In the office or operation room, we can (inject) a material next to the vocal cord that pushes it into a more natural position, so it can get closure. (We then) watch and hope it recovers on its own,” Maronian said. Page said in his statement that he plans to “fund a significant research program” through the Vocal Health Institute, led by Dr. Steven Zeitels from the Harvard Medical School and the Massachusetts General Hospital Voice Center.source : http://www.foxnews.com/health/2013/05/16/vocal-cord-paralysis-explaining-google-ceo-larry-pages-rare-condition/

Tiny preemies get a boost from live music therapy

As the guitarist strums and softly sings a lullaby in Spanish, tiny Augustin Morales stops squirming in his hospital crib and closes his eyes. This is therapy in a newborn intensive care unit, and research suggests that music may help those born way too soon adapt to life outside the womb. Some tiny preemies are too small and fragile to be held and comforted by human touch, and many are often fussy and show other signs of stress. Other common complications include immature lungs, eye disease, problems with sucking, and sleeping and alertness difficulties. Recent studies and anecdotal reports suggest the vibrations and soothing rhythms of music, especially performed live in the hospital, might benefit preemies and other sick babies. Many insurers won't pay for music therapy because of doubts that it results in any lasting medical improvement. Some doctors say the music works best at relieving babies' stress and helping parents bond with infants too sick to go home. But amid beeping monitors, IV poles and plastic breathing tubes in infants' rooms at Chicago's Ann & Robert H. Lurie Children's Hospital, music therapist Elizabeth Klinger provides a soothing contrast that even the tiniest babies seem to notice “What music therapy can uniquely provide is that passive listening experience that just encourages relaxation for the patient, encourages participation by the family,” Klinger said after a recent session in Augustin's hospital room. The baby's parents, Lucy Morales and Alejandro Moran, stood at the crib and whispered lovingly to their son as Klinger played traditional lullabies, singing in Spanish and English. “The music relaxes him, it makes him feel more calm” and helps him sleep better too, Lucy Morales said. “Sometimes it makes us cry.” Some families request rock music or other high-tempo songs, but Klinger always slows the beat to make it easier on tender ears. “A lot of times families become afraid of interacting with their children because they are so sick and so frail, and music provides them something that they can still do,” Klinger said, who works full time as a music therapist but her services are provided for free. Music therapists say live performances in hospitals are better than recorded music because patients can feel the music vibrations and also benefit from seeing the musicians. More than two dozen U.S. hospitals offer music therapy in their newborn intensive care units and its popularity is growing, said Joanne Loewy, a music therapist who directs a music and medicine program at Beth Israel Medical Center in New York. Preemies' music therapy was even featured on a recent episode of the hit TV show “American Idol,” when show finalist Kree Harrison watched a therapist working with a tiny baby at Children's Hospital Los Angeles. “Music is such a huge part of our lives and to do something like this, make it a sort of healing process, is a cool thing,” Harrison said on the April 25 episode. Dr. Natalia Henner, a newborn specialist at Lurie hospital, said studies in nursing journals show music therapy for preemies “does help with promoting growth. And there's some good literature ... saying that the time to discharge is a little bit shorter in babies who've been exposed to more music therapy.” She said it “definitely facilitates bonding” between parents of preemies and other babies too sick to go home. Loewy led a study published last month in the journal Pediatrics, involving 11 U.S. hospitals. Therapists in the study played special small drums to mimic womb sounds and timed the rhythm to match the infants' heartbeats. The music appeared to slow the infants' heartbeats, calm their breathing, and improve sucking and sleeping, Loewy said. Soozie Cotter-Schaufele, a music therapist at Advocate Children's Hospital-Park Ridge near Chicago, says soothing rhythmic sounds of music can mimic womb sounds and provide a comforting environment for preemies. She sings and plays a small harp or guitar, and says the sounds help calm tiny babies while they're undergoing painful medical procedures. Cotter-Schaufele said she recently heard from a woman whose daughter was born prematurely at her hospital six years ago. She had played the 1960s folk song “Today” for the infant. The mother reported her daughter “`still loves that song,” She said `She didn't learn that song from me, she learned it from you,'” Cotter-Schaufele said.source : http://www.foxnews.com/health/2013/05/16/tiny-preemies-get-boost-from-live-music-therapy/

New cancer tools allow patients to reconsider chemo

After decades of using one-size-fits-all therapies to combat cancer, doctors are using new tools to help decide when their patients can skip chemotherapy or other harsh treatments. An approach to oncology that has been in place for decades is beginning to yield to an arsenal of long-term clinical studies, genetic tests and novel drugs that target cancer cells and their infrastructure. “What is happening is a combination of new technology and more-targeted cancer drugs,” said Dr Sandra Swain, medical director of the Cancer Institute at Washington Hospital Center and president of the American Society of Clinical Oncology (ASCO). “We've tried the approach of big, nonspecific treatments ... We have found that throwing chemo at patients has not (necessarily) cured them.” Traditional chemotherapy drugs work by interfering with the entire body's system of cell replication, causing harsh side effects like fatigue and hair loss. Since the completion of the human genome project in 2003, scientists have made progress in unlocking the genetic basis of a range of diseases, including cancer. That has paved the way for genetic testing as well as drugs that block specific pathways that cancer cells use to grow and reproduce. Such targeted cancer drugs, which sometimes preclude the need for chemotherapy, are being sold by companies ranging from Pfizer Inc, the world's largest drugmaker, to Ariad Pharmaceuticals Inc, which early this year launched its first drug, to treat leukemia. At the same time, large-scale studies that look at whether some types of patients are better off with less treatment are giving doctors more confidence to hold off on using traditional cancer drugs. Laurie Levin, now 64, was successfully treated in her 20s for non-Hodgkin's lymphoma, but faced a dilemma after being diagnosed with breast cancer in 2005 since the earlier radiation and chemotherapy had already raised her risk of developing heart problems or leukemia. A $4,000 genetic test showed that her breast cancer was unlikely to return, providing the confidence to undergo a lumpectomy and avoid chemotherapy. “It was like someone handed me my life back when I got those results,” she said. Use of the Oncotype DX test, which analyzes genes involved in tumor recurrence, has cut the use of chemotherapy in U.S. breast cancer patients by 20 percent over the past eight years, according to its maker, Genomic Health Inc. The company recently launched a similar test designed to measure whether men with prostate cancer need to undergo surgery or radiation. Tests and studies can clarify treatment, but costs remain on the upswing because the newest drugs are very expensive, with monthly price tags often in the thousands of dollars. By 2016 annual global sales of cancer drugs will nearly triple, to $88 billion from a decade earlier, according to IMS Health. 'RIGHT-SIZING TREATMENT' The “less is more” approach to cancer will be one highlight of ASCO's annual meeting in Chicago that begins at the end of this month. On Wednesday, ASCO released thousands of abstracts on new clinical trials of cancer treatments. One large, long-term study found that most men diagnosed with early-stage seminoma, a common type of testicular cancer, did fine with no treatment following surgery to remove the tumors. Cure rates for the disease have always been quite high. Several European countries, including Denmark where the study was conducted, monitor seminoma patients for any relapse before further treatment. In the United States, about half of early-stage patients are still given radiation or chemotherapy, according to ASCO. “Opting for surveillance spares patients, most of whom are young men, from the harmful side effects of chemotherapy and radiation without diminishing their chances for a long and healthy life,” said ASCO's incoming president, Dr Clifford Hudis, in a statement. Physicians say it is difficult to quantify in statistics, but there is growing recognition that less is more in terms of potentially toxic cancer treatments. The approach is especially important for young patients who will have many years ahead of them after beating an initial bout of cancer. “We are right-sizing treatment,” said Dr. James Mohler, chair of the department of urology at Roswell Park Cancer Institute in Buffalo, New York. He pointed to recent national guidelines calling for “active surveillance” of older men diagnosed with slower-growing prostate cancer. A study presented earlier this year at an ASCO meeting in Florida found similar survival rates for men with high-risk prostate cancer who received radiation and either 18 or 36 months of hormone therapy. The findings suggest the therapy, which causes significant side effects, could be given for less than the current standard of 24 to 36 months. Another recent study out of the Duke Cancer Institute in Durham, North Carolina, found that survival odds for women with early-stage breast cancer who underwent breast-preserving surgery such as lumpectomy were as good as, or even better than, the odds for women who had mastectomies. “We are going to see reevaluations of very successful therapies to determine whether or not we can achieve the same results using less treatment,” said Dr Armand Keating, director of the hematology division at the University of Toronto and president of the American Society of Hematology. The first-ever study showing that a type of leukemia could be cured without using chemotherapy was released in December. The Italian-German study found that a combination of a derivative of vitamin A, known as ATRA, and arsenic trioxide, a newer drug, worked as well as ATRA and chemotherapy in patients newly diagnosed with acute promyelocytic leukemia (APL). “APL used to be one of the most dreaded strains of cancer, but with ATRA and chemo the results are very gratifying,” Keating said. “Now we have two agents that are not chemo agents ... That to me is a milestone. I can't see any reason why this wouldn't become the standard of care.” A recent trial conducted in France found that omitting standard chemotherapy, which has been linked to heart damage, from the initial treatment of a type of childhood leukemia did not reduce survival outcomes. “The nice thing is you have omitted a potentially toxic agent that contributes to morbidity and maybe mortality down the road,” Keating said. The priciest therapies are designed to take advantage of genetic mutations associated with cancer cells, some of them found only in a small percentage of patients. A new drug for melanoma, BRAF inhibitor Zelboraf from Roche Holding AG, is designed to work by targeting a specific genetic mutation found in about half of all melanomas. Patients are first tested to see if they have it. Pfizer's lung-cancer drug Xalkori, which targets a mutation in the ALK gene, works in about 4 percent of lung cancer patients. It also has been effective as a treatment for a rare but aggressive type of childhood lymphoma. “We've been really trying for years to be more precise about who needs treatment ... Now we are more able to achieve it,” said Swain.source : http://www.foxnews.com/health/2013/05/16/new-cancer-tools-allow-patients-to-reconsider-chemo/

Skin cancer may be linked to lower risk of Alzheimer’s disease

The study involved 1,102 people with an average age of 79 who did not have dementia at the start of the study. The participants were followed for an average of 3.7 years. At the start of the study, 109 people reported that they had skin cancer in the past. During the study, 32 people developed skin cancer and 126 people developed dementia, including 100 with Alzheimer’s dementia. …