Mortality risk of overweight, obesity similar for blacks, whites
For the study, researchers led by Alpa V. Patel, Ph.D., analyzed data from the Cancer Prevention Study II (CPS-II), a large, prospective study. …
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Endometrial, colon cancers: Study indicates possible new way to treat
In the quest to solve cancer’s mysteries, they come in handy when describing tongue-twisting processes and pathways that somehow allow tumors to form and thrive. …
Cell migration: How it works, how new discovery may inform cancer research
Cells migrate by connecting their cytoskeleton — a network made up of proteins — to adhesion molecules which in turn get in contact with the surrounding connective tissue. In order to guide cells in a certain direction a signal from outside is needed, which leads then to cell polarization and coordinated mechanical movement. A fundamental question is how signaling pathways are regulated in time and space to facilitate directional migration of cells…
The skin cancer selfie: Gigapixel camera helps diagnose early
Developed by a team of researchers at Duke University in North Carolina, USA, the “gigapixel whole-body photographic camera” is essentially three dozen cameras in one, allowing the researchers to image the entire body down to a freckle. The research will be presented at The Optical Society’s (OSA) 98th Annual Meeting, Frontiers in Optics, being held Oct. 19-23 in Tucson, Arizona, USA. …
First pictures of BRCA2 protein show how it works to repair DNA — ScienceDaily
Mutations in the gene that encodes BRCA2 are well known for raising the risk of breast cancer and other cancers. Although the protein was known to be involved in DNA repair, its shape and mechanism have been unclear, making it impossible to target with therapies. …
Neuroscientists use snail research to help explain ‘chemo brain’
In an effort to solve this mystery, neuroscientists at The University of Texas Health Science Center at Houston (UTHealth) conducted an experiment in an animal memory model and their results point to a possible explanation. Findings appeared in The Journal of Neuroscience. In the study involving a sea snail that shares many of the same memory mechanisms as humans and a drug used to treat a variety of cancers, the scientists identified memory mechanisms blocked by the drug. …
Gene can predict aggressive prostate cancer at diagnosis — ScienceDaily
The results reported in the journal of Clinical Cancer Research, a publication of the American Association of Cancer Research, indicate the KLK3 gene — a gene on chromosome 19 responsible for encoding the prostate-specific antigen (PSA) — is not only associated with prostate cancer aggression, but a single nucleotide polymorphism (SNP) on it is more apparent in cancer patients with GS7. Researchers have linked Gleason score, an important predictor of prostate cancer outcomes, to several clinical end points, including clinical stage, cancer aggression and survival. …
Help explain ‘chemo brain’ through snail research
In an effort to solve this mystery, neuroscientists at The University of Texas Health Science Center at Houston (UTHealth) conducted an experiment in an animal memory model and their results point to a possible explanation. Findings appeared in The Journal of Neuroscience. In the study involving a sea snail that shares many of the same memory mechanisms as humans and a drug used to treat a variety of cancers, the scientists identified memory mechanisms blocked by the drug. Then, they were able to counteract or unblock the mechanisms by administering another agent. …
New educational modules harness power of e-learning for pancreatic cancer education
The ePOSSOM endeavour was jointly developed by ecancer and the Severn Postgraduate School of Surgery, where surgical trainees led by Miss Katrina Butcher developed the content of the modules, providing key educational information for other surgical trainees and healthcare professionals. “ePOSSOM creates innovative e-learning material for audiences across the world, allowing each learner access to complex evidence-based medicine, wherever their learning environment allows them,” Miss Butcher writes in the accompanying editorial. These modules follow the UK ISCP (Intercollegiate Surgical Curriculum Programme) Curriculum, and aim to be a concise, up-to-date best evidence resource, for either new learning or revision. Experts from across the UK have contributed to and peer-reviewed the modules to ensure that the content is of the highest scientific quality — and poised on the frontier of pancreatic cancer knowledge. …
Knowledge empowers: Regular mammograms reduce breast cancer deaths — ScienceDaily
“In 2014, nearly 300,000 women will be diagnosed with breast cancer in the U.S. Even though mammography has helped reduce the breast cancer death rate in the United States by more than 30 percent since 1990, and every major medical organization with expertise in breast cancer diagnosis and treatment recommends annual mammograms for women 40 and older, thousands will die in the next 12 months because they did not get a mammogram…