Tag Archives: journal

Researchers develop tool to determine individual risk of prostate cancer overdiagnosis

Now, researchers at Fred Hutchinson Cancer Research Center and the University of Washington have developed a personalized tool that can predict the likelihood of prostate cancer over-diagnosis. They announced their findings this week in the online issue of the Journal of the National Cancer Institute…

Nomogram to determine individualized estimates of screen-detected prostate cancer overdiagnosis

The authors used a standard definition of overdiagnosis to refer to a cancer that would not have become symptomatic or clinically identifiable if it had not been detected by screening. Overdiagnosed cancers do not pose a risk to the patient and do not require treatment, which is associated with significant risks of impotence and incontinence. …

Fresh faced: Looking younger for longer

Publishing in The FASEB Journal, the authors describe how in laboratory tests, they compared the protection offered against either UVA radiation or free radical stress by several antioxidants, some of which are found in foods or cosmetics. While UVB radiation easily causes sunburn, UVA radiation penetrates deeper, damaging our DNA by generating free radicals which degrades the collagen that gives skin its elastic quality…

BPA increases risk of cancer in human prostate tissue, study shows

Bisphenol A, or BPA, is widely used to soften plastics. Steering clear of the chemical is nearly impossible, says Gail Prins, professor of physiology at UIC and lead author of the paper. "Previous studies have shown that people who avoided all contact with plastics or other BPA-containing objects for up to a month or more still had BPA in their urine, which means they must have come into contact with BPA in the last 24 to 48 hours, since it clears the body rather quickly," said Prins, who is director of the UIC andrology laboratory. "It’s very hard to avoid." Exposure of the fetus to BPA in utero is of particular concern, because the chemical, which mimics the hormone estrogen, has been linked to several kinds of cancer, including prostate cancer, in rodent models…

Promising new biomarkers linked to early diagnosis of breast cancer

Cancer is the second leading cause of death in both men and women in the U.S. However, women have a higher chance than men of being diagnosed with cancer before the age of 60 due to breast cancer development. Metastases in breast cancer’s later stages cause the majority of deaths associated with the disease, making early detection crucial to patient survival. …

Cancer Statistics 2014: Death rates continue to drop

Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute and the Centers for Disease Control and Prevention, and mortality data from the National Center for Health Statistics. The data are disseminated in two reports, Cancer Statistics, published in CA: A Cancer Journal for Clinicians, and its companion article, Cancer Facts & Figures. This year’s report estimates there will be 1,665,540 new cancer cases and 585,720 cancer deaths in the United States in 2014…