Tag Archives: disease

Up to 1 in 5 children suffer from a mental disorder, CDC says

Up to 20 percent of children in the United States suffer from a mental disorder, and the number of kids diagnosed with one has been rising for more than a decade, according to a report released on Thursday by the U.S. Center for Disease Control and Prevention. In the agency's first-ever study of mental disorders among children aged 3 to 17, researchers found childhood mental illnesses affect up to one in five kids and cost $247 billion per year in medical bills, special education and juvenile justice. Children with mental disorders - defined as “serious deviations from expected cognitive, social, and emotional development” - often have trouble learning in school, making friends, and building relationships later in life, the report said. They are more likely to have other chronic health problems, such as asthma and diabetes, and are at risk for developing mental illnesses as adults. “This is a deliberate effort by CDC to show mental health is a health issue. As with any health concern, the more attention we give to it, the better. It's parents becoming aware of the facts and talking to a healthcare provider about how their child is learning, behaving, and playing with other kids,” Dr. Ruth Perou, the lead author of the study, said in an interview. “What's concerning is the number of families affected by these issues. But we can do something about this. Mental health problems are diagnosable, treatable and people can recover and lead full healthy lives,” Perou added. The study cited data collected between 1994 and 2011 that showed the number of kids with mental disorders is growing. The study stopped short of concluding why, but suggested improvements in diagnoses as one possible explanation “Changes in estimated prevalence over time might be associated with an actual change in prevalence, changes in case definition, changes in the public perception of mental disorders, or improvements in diagnosis, which might be associated with changes in policies and access to health care,” the study said. Perou said more research was needed to determine the specific causes of mental disorders, and that greater awareness could lead to an uptick in diagnoses. A host of environmental factors, including chemical exposure and poverty, can also affect a child's mental health, she said. Lead, for example, is known to be “one of the biggest toxins to impact behavior and learning,” Perou said. Poor children are at a higher risk for developing certain conditions, according to the study. The most prevalent mental health diagnosis, as reported by parents, was Attention Deficit/Hyperactivity Disorder (ADHD), which affects 6.8 percent of children. Also common were behavioral conduct problems (3.5 percent), anxiety, which consists mostly of fears and phobias (3 percent), depression (2.1 percent) and autism spectrum disorders (1.1 percent). Many of these disorders occur together, the report said. Boys were found more likely to have most of the listed disorders except for depression and alcohol abuse, which affect more girls. The study also noted that suicide, which can be precipitated by an untreated mental illness, was the second leading cause of death (after accidents) among children 12 to 17 years old. The CDC report was based on multiple other studies that collected data and interviewed children and their guardians about their diagnoses, habits, behaviors and other factors.source : http://www.foxnews.com/health/2013/05/17/up-to-1-in-5-children-suffer-from-mental-disorder-cdc-says/

When it comes to cancer, information is power

Noreen asked me to fill in for her today.  Don't worry, she has actually been feeling better this past week.  She got to take a break from chemo, which always makes her feel better, and she learned her tumor markers dropped from 600 to 53!  We are very excited about that bit of news. The reason I am writing this week is because there has been a lot of attention given to the announcement by Angelina Jolie that she underwent a preventative double mastectomy with reconstruction when she learned she had the BRCA (BReast CAncer ) gene.   I, too, had the surgery after testing positive for the gene.  People, myself included, were stunned by Angelina's announcement.  When one of the most famous and arguably beautiful women in the world has a preventative mastectomy, it sheds a spotlight on the issue and reminds us that not even fame and fortune can save us from cancer.   Since Angelina “came out,” breast cancer advocates, doctors, news commentators and others have given their opinions on whether or not Angelina and other women with the breast cancer gene and/or breast cancer have made the “right” decision by having a double mastectomy. But there is no “right” or “wrong” in these situations.  No one wants a mastectomy . . . no one.  Women (and some men) choose the long, painful and disfiguring surgery to either remove cancer from their bodies or to try and prevent it when they have a greatly increased risk of getting breast cancer.    Angelina and I had an 87 percent chance of developing breast cancer.  Eighty-seven percent! You have all followed Noreen's blogs.  She is one of my closest friends.  When I compared having a mastectomy to what she has endured, for me, a mastectomy felt like the better option.   Still, the message I want to send is that surgery is not the only option for women who have the breast cancer gene or otherwise have an increased risk. The important thing is that you don't keep your head in the sand.  Information is power.  You should talk to your health care provider and determine whether you are at an increased risk.   If testing for the breast cancer gene is recommended, just remember your life won't change if you find out you have it; you just have more information so you can explore more options.   Surgery is just one option.  Women at high risk are also eligible for increased screenings, which could help “catch” cancer early and give you a fighting chance if you do develop the disease.   Like I said, there is no right or wrong answer, but when you have all of the information, you can determine what option is best for you.     Noreen will be back next week.  Until then, keep up with her on Facebook    Michelle McBride is the President of the Noreen Fraser Foundation.source : http://www.foxnews.com/health/2013/05/15/when-it-comes-to-cancer-information-is-power/

India developing cheap vaccine against major cause of diarrhea deaths in kids

The Indian government announced Tuesday the development of a new low-cost vaccine proven effective against a diarrhea-causing virus that is one of the leading causes of childhood deaths across the developing world. The Indian manufacturer of the new rotavirus vaccine pledged to sell it for $1 a dose, a significant discount from the cost of the current vaccines on the market. That reduced price would make it far easier for poor countries to vaccinate their children against the deadly virus, health experts said. Rotavirus, spread through contaminated hands and surfaces, kills about half a million children across the world each year, 100,000 of them in India. At a conference Tuesday, the government announced that Phase III trials of Rotavac proved that it was safe as well as effective. The clinical trial of 6,799 infants at three sites in India showed the vaccine reduced severe cases of diarrhea caused by rotavirus by 56 percent during the first year of life. “The clinical results indicate that the vaccine, if licensed, could save the lives of thousands of children each year in India,” said Dr. K. Vijay Raghavan, the secretary of the Department of Biotechnology. The vaccine still needs to be licensed before it can be distributed in India and would require further approval by the World Health Organization before it could be distributed globally. Two other vaccines have proven effective against rotavirus, but they are significantly more expensive. The GAVI Alliance, which works to deliver vaccines to the world’s poor, negotiated a significant discount last year with GlaxoSmithKline and Merck, obtaining the rotavirus vaccines from those pharmaceutical companies for $2.50 a dose. The alliance has programs for delivering those vaccines in 14 countries and plans to expand them to 30 countries. Dr. Seth Berkley, the GAVI Alliance’s CEO, said the announcement Tuesday was “a big deal.” “The cheaper the price the more children you can immunize,” he said, adding that it will still take some time before the vaccine is approved for use. In addition, having a third manufacturer for the vaccines would ease supply shortages and could drive down the costs charged by the other manufacturers, he said. “That would make a big difference in terms of changing the marketplace,” he said. Diarrhea is the second leading cause of death among young children in the world after pneumonia. A study of 22,568 children at sites in seven African and south Asian countries that was published Monday in the medical journal The Lancet showed that rotavirus was the leading cause of moderate to severe diarrhea in children under the age of two. The new vaccine was developed from a weakened strain of the virus taken from a child hospitalized in New Delhi more than a quarter century ago. It was the result of a broad global partnership that included the government, the Indian company Bharat Biotech, the Bill and Melinda Gates Foundation and the U.S. Centers for Disease Control and Prevention, among many others. Those involved said the broad cooperation reduced research costs for the manufacturer and helped keep the vaccine inexpensive. “This public-private partnership is an exemplary model of how to develop affordable technologies to save lives,” Bill Gates, co-chair of the Gates Foundation, said in a statement.source : http://www.foxnews.com/health/2013/05/15/india-developing-cheap-vaccine-against-major-cause-diarrhea-deaths-in-kids/

Leap in leukemia treatment

CLL lives both in the blood in circulation, and in lymph nodes and bone marrow. The former is relatively easy to kill, but the disease recurs because of resistant CLL cells in the lymph nodes and bone marrow. The researchers found an innovative drug combination that targets the stubborn CLL cells. "We have been studying the mechanism in the cancer cells that causes the resistance to treatment," says Alan Eastman, the senior researcher on the team and a professor of pharmacology and toxicology at the Geisel School of Medicine at Dartmouth, "and that in turn, led us to find drugs that target the resistance." Eastman led the team at Dartmouth-Hitchcock’s Norris Cotton Cancer Center that also included Ryan Soderquist, Darcy Bates, and Alexey Danilov. …

Tumor-activated protein promotes cancer spread

The findings are published in this week’s online Early Edition of the Proceedings of the National Academy of Sciences. Roughly 90 percent of all cancer deaths are due to metastasis — the disease spreading from the original tumor site to multiple, distant tissues and finally overwhelming the patient’s body. Lymph vessels are often the path of transmission, with circulating tumor cells lodging in the lymph nodes — organs distributed throughout the body that act as immune system garrisons and traps for pathogens and foreign particles. The researchers, led by principal investigator Judith A. …

Vietnam War chemical tied to aggressive prostate cancer risk

Men who were exposed to Agent Orange chemicals used during the Vietnam War are at higher risk for life-threatening prostate cancer than unexposed veterans, researchers have found. What's more, those who served where the herbicide was used were diagnosed with cancer about five years earlier than other men, on average, in the new study. “This is a very, very strong predictor of lethal cancer,” said urologist Dr. Mark Garzotto, who worked on the study at the Portland Veterans Affairs Medical Center in Oregon. “If you're a person who's otherwise healthy and you've been exposed to Agent Orange, that has important implications for whether you should be screened or not screened,” he told Reuters Health. But one researcher not involved in the new study said it's hard to take much away from it, given the imprecise way it measured exposure. Agent Orange - named after the giant orange drums in which the chemicals were stored - was used by the U.S. military to destroy foliage, mainly in southern Vietnam. The herbicide was often contaminated with a type of dioxin, a potently carcinogenic chemical. The Vietnam Red Cross Society has estimated that up to one million Vietnamese suffered disabilities or health problems as a result of Agent Orange, including children born with birth defects years after their parents were exposed. Past research has also suggested that U.S. veterans who served where Agent Orange was used are at an increased risk of lymphoma and certain other cancers, including prostate cancer. For the new study, researchers wanted to see whether exposure was more closely linked to slow-growing prostate cancers or aggressive tumors. They analyzed medical records belonging to 2,720 veterans who were referred to the Portland VA for a prostate biopsy. About one in 13 of those men had been exposed to Agent Orange during the Vietnam War, according to their VA intake interviews. One third of all men in the study were diagnosed with prostate cancer, about half of which were high-grade cancers - the more aggressive and fast-growing type. When the researchers took men's age, race, weight and family history of cancer into account, they found those with Agent Orange exposure were 52 percent more likely than unexposed men to have any form of prostate cancer. Separating out different types of tumors showed the herbicide was not linked to an increased risk of slower-growing, low-grade cancer. But it was tied to a 75 percent higher risk of being diagnosed with aggressive prostate cancer, the study team reported Monday in the journal Cancer. “The increase in the rate of cancers was almost exclusively driven by the potentially lethal cancers,” said Garzotto, also from Oregon Health & Science University. More research is needed to figure out exactly why that is, he said. In the meantime, Garzotto said veterans who were exposed to Agent Orange should discuss that with their doctors. But Dr. Arnold Schecter, from the University of Texas School of Public Health's Environmental and Occupational Health Sciences Program in Dallas, said there's a “big problem” with just asking veterans if they were exposed to Agent Orange or served in an area where it was sprayed. “Of those most heavily exposed in the military as best we know, only a relatively small percentage of them had elevated dioxin from Agent Orange in their blood when tested by (the U.S. Centers for Disease Control and Prevention),” he told Reuters Health. Schecter said that in Vietnam, people who have high levels of that type of dioxin in their blood live in places where the chemical has become integrated into the food supply - or were sprayed directly with Agent Orange. Another researcher who has studied the effects of Agent Orange agreed that not having blood dioxin levels is a drawback, but said the findings are consistent with past research and general thinking about the chemical. “Almost all studies have implicated that men with Agent Orange (exposure) either have higher-grade prostate cancer or a more aggressive clinical course,” said Dr. Gregory Merrick, head of Wheeling Hospital's Schiffler Cancer Center in West Virginia, who also wasn't involved in the new research. But, he added, as long as men are getting into the VA system and getting regular evaluations and treatment for cancer, Agent Orange exposure “is not a death sentence by any means.”source : http://www.foxnews.com/health/2013/05/13/vietnam-war-chemical-tied-to-aggressive-prostate-cancer-risk/

Four new genetic risk factors for testicular cancer identified

The discovery of these genetic variations — chromosomal "typos," so to speak — could ultimately help researchers better understand which men are at high risk and allow for early detection or prevention of the disease. "As we continue to cast a wider net, we identify additional genetic risk factors, which point to new mechanisms for disease," said Katherine L. Nathanson, MD, associate professor in the division of Translational Medicine and Human Genetics within the department of Medicine. …

How to treat painful sex

Dyspareunia is the technical term for pain during sexual intercourse, which can be related to mental or physical causes. It is not uncommon for women to experience painful intercourse at some point in their lives.   If you are experiencing pain during intercourse, work with your physician to determine the root cause and devise an effective treatment plan. For some of the most common reasons for painful sex, there are simple solutions that can get your sex life back on track. 1. Vaginal dryness Poor vaginal lubrication is classically linked to insufficient levels of estrogen, which tend to decline following pregnancy, during menopause and with treatments for breast cancer. This condition, however, is something women should be discussing with their doctors. Vaginal dryness can be a result of more serious conditions, such as the autoimmune disease, Sjogren’s syndrome.  It may also be caused by medications, such as oral birth control, beta-blockers and antidepressants. Regardless of the cause, intercourse is often very painful and many women may lose the desire to have sex or may be inclined to endure unhealthy pain in the attempt to appease their partner. There are several treatment options for vaginal dryness: • Hormone therapy, such as restoring estrogen and progesterone levels to normal levels can bring back the natural mechanism that supports vaginal lubrication. • Adequate amounts of mono- and polyunsaturated fats in your diet (10 to 20 percent of daily calories). • Stay hydrated to keep the body’s mucous membranes moist and functioning. • Avoid products that can steal vaginal moisture, like feminine sprays, douches and antibacterial and deodorant soaps • Use an all-natural, water-based lubricants. 2. Lichen sclerosis Lichen sclerosis is a fairly common issue among women that affects the vulva and can cause intercourse to be painful.  The issue can cause progressive changes to the vulvar skin. Generally, small white spots appear on the skin with a shiny or smooth texture. These can grow into larger patches and the skin will become thin and crinkled and may bruise or tear easily. Other symptoms include itching, pain, bleeding and blisters. Women experiencing these symptoms should seek the advice of the physician, as lichen sclerosis has been associated with an increased risk for vulvar cancer. The condition is treatable, usually with topical steroids, but once diagnosed the condition generally affects the individual for a lifetime. 3. Birth control pills Painful intercourse may also be associated with use of birth control pills. It is not uncommon for oral birth control to cause hormonal issues that can lead to discomforts during sex.  Birth control pills cause elevated levels of sex hormone binding globulin, which can bind free testosterone and cause vaginal atrophy in young women. This problem may persist even after discontinuation of the Pill. Hormone replacement therapy is an effective treatment option to return hormone levels to a balanced, natural state and improve pain with intercourse. 4. Vulvodynia Vulvodynia is a pain syndrome of the vulva that is characterized by point hypersensitivity to touch usually in the introitus (entrance to the vagina.)  This can be the result of having frequent vaginal infections, particularly yeast infections. Women that are susceptible to frequent yeast infections should avoid potential irritants, like douches, dyes and perfumes. It is important to the vulva clean and dry and use lubrication with intercourse. If yeast infections continue or pain occurs with intercourse, you should seek treatment you’re your doctor. A healthy diet, as well as oral and vaginal probiotics, are effective treatments options to minimize the occurrence of yeast infections and prevent the development of disease.  Some physicians may prescribe chronic use of steroids to treat vulvodynia; however, this is not the best solution. Chronic steroids, especially potent doses, thin the vaginal skin over time, which can increase pain.  Topical numbing medications, or even injections of interferon, are better alternatives for managing the condition. 5. Vaginismus In some cases, the issue of painful sex is involuntary tightening of the pelvic floor muscles, which is known as vaginismus. This can be diagnosed with an examination by your physician. Pelvic floor physical therapy is the best course of treatment, followed by graduated use of vaginal dilators.   6. Deep pain Deep pain during intercourse can be caused by a number of factors, including certain types of cancer, endometriosis, fibroids and polycystic ovary syndrome (PCOS). Getting treatment early can prevent the dangerous progression of these conditions, which may threaten not only your sex life, but your fertility and health. Do not hesitate to discuss the occurrence with your physician. 7. Seek a physician’s care If you experience internal pain with sex, you should discuss this with your doctor. If the pain is only occasional, it may be related to your cycle, or perhaps the particular position may not be comfortable for you. However, if the pain reoccurs consistently or becomes worse, this could indicate inflammation — which means it's time to see a doctor.   Dr. Jennifer Landa is Chief Medical Officer of BodyLogicMD, the nation's largest franchise of physicians specializing in bioidentical hormone therapy. Dr. Jen spent 10 years as a traditional OB-GYN, and then became board-certified in regenerative medicine, with an emphasis on bio-identical hormones, preventative medicine and nutrition. She is the author of “The Sex Drive Solution for Women.” & Learn more about her programs at www.jenlandamd.com.& source : http://www.foxnews.com/health/2013/05/12/how-to-treat-painful-sex/