Tag Archives: depression

Common anesthetic can reduce chronic pain after mastectomy — ScienceDaily

“Unfortunately, chronic pain is a condition that many breast cancer patients endure after mastectomy,” said Mohamed Tiouririne, M.D., lead author and associate professor of anesthesiology at the University of Virginia, Charlottesville. “Our findings indicate that intravenous (I.V.) lidocaine can protect mastectomy patients from developing chronic pain, possibly due to the anti-inflammatory effects associated with the medication.” In the study, 61 women who underwent mastectomy were randomly divided into two groups…

Acupuncture provides significant quality of life improvements among breast cancer patients taking drugs to prevent recurrence, study shows

The results build upon earlier findings reported in November 2013, showing that EA can decrease the joint pain reported by roughly 50 percent of breast cancer patients taking AIs — the most-commonly prescribed medications to prevent disease recurrence among post-menopausal women with early-stage, hormone receptor positive breast cancer. Despite their efficacy, the joint pain associated with the use of AIs often leads to fatigue, anxiety, depression, and sleep disturbances for these patients, which researchers suggest may cause premature discontinuation of the drug. …

Treating depression: One size does not fit all

Nearly 15 million U.S. adults suffer from clinical depression. Treating them is currently a process of trial and error. “It's always been a combination of physician preference, patient preference and… who you actually choose to see for your depression,” Dr. Helen Mayberg, a neurologist at Emory University School of Medicine, said. “If you choose to go see a psychologist, psychologists do therapy. If you go to your family doctor… the likelihood is that you'll be prescribed a medication.” With fewer than 40 percent of patients achieving success with their initial treatment for depression, the majority have to wait to see if additional therapies are effective. “It's a serious illness,” Mayberg said. “There are consequences to going another six weeks, another eight weeks, another 12 weeks on a treatment that is unlikely to work.” Now, Mayberg and a team of researchers may have discovered a way to reduce the guesswork involved with treating clinical depression. Their study, published online in JAMA Psychiatry, suggests the solution is locked in a portion of the brain called the anterior insula. PET scans revealed that patients who benefitted from escitalopram (an antidepressant also known by the brand name Lexapro) had different activity levels in the anterior insula than patients who responded well to “talk therapy.” “The patients who did the best on escitalopram have high insula activity (compared to other parts of the brain),” Callie McGrath, an Emory graduate student and lead author of the study, said. “And the patients who do the best on cognitive behavioral therapy have low insula activity.” The researchers believe they've found the first reliable indicator to guide doctors in their selection of initial treatments for clinical depression. This has the potential to spare many patients from the prolonged suffering and uncertainty associated with current trial and error methods. “It's a very discouraging process,” said Edi Guyton, who leads local support programs with the National Alliance on Mental Illness (NAMI). “It's long. You begin to feel hopeless.” Guyton said she struggled with treatment-resistant depression for most of her life until she was able to bring it under control through deep brain stimulation (DBS), an experimental therapy developed by Dr. Mayberg. Guyton said she hopes Mayberg's separate study on the relationship between brain activity and treatment outcomes will lead to more research that takes the hit and miss factor out of helping people with depression. “That would be wonderful, just knowing what medicine,” Guyton said. “If you were pretty sure, even 80 percent sure, that this is gonna work for me, I think it would make all the difference in the world.”source : http://www.foxnews.com/health/2013/06/13/depression-treatments-brain-scans-may-suggest-best-course/

10 signs you may have obsessive-compulsive disorder

Hooked on hand sanitizer? Closet organized to a T? Quirks like this can usually be chalked up to personality or preference, but in some cases they may point to a more serious issue: obsessive-compulsive disorder (OCD), a condition marked by obsessive thoughts and compulsions that affects about 1 percent of U.S. adults. How can you tell if OCD tendencies are symptoms that require professional help? There's no easy test, as it's usually a matter of degree, said Jeff Szymanski, executive director of the International OCD Foundation, a Boston-based advocacy organization. Still, there are certain patterns that may indicate the full-blown disorder. Here are 10 of the most common. Hand-washing Compulsive hand-washing or hand sanitizer use is so prevalent in OCD that “washers” has become a widely accepted category of OCD patient. The urge commonly stems from a fear of germs (the most common obsession seen in OCD), but it also can be rooted in fears of making others sick or of being impure or immoral. When to seek help: If you think about germs even after washing your hands, worry that you're not scrubbing well enough, or have irrational fears about disease (such as getting HIV from a shopping cart), it could be a sign that your hand-washing is compulsive, Szymanski said. Elaborate hand-washing routines—needing to wash five times and get soap under each nail, for example—are another warning sign. Health.com: Do You Have an Anxiety Disorder…