Tag Archives: department

Mysterious respiratory illness kills 2, leaves 5 others hospitalized in Alabama

MONTGOMERY, Ala. – & A mysterious respiratory illness has left five people hospitalized and two dead in southeast Alabama, state health officials said Tuesday. Seven people have been admitted to hospitals with a fever, cough and shortness of breath in recent weeks, Alabama Department of Public Health spokeswoman Mary McIntyre said in a statement. Two of the seven have died. The Alabama Department of Public Health and the Centers for Disease Control Respiratory Laboratory are analyzing lab tests from all seven patients. McIntyre says officials hope to have preliminary results on the samples back by Wednesday or Thursday morning. The illness was first reported late last week and the last of the seven patients was hospitalized Monday, McIntyre said. It wasn't immediately clear which municipalities the illnesses were concentrated in. “We're only aware of the Southeast, but we don't know -- we haven't received reports from anywhere else,” McIntyre said. “That's why we're trying to get the information out.” McIntyre said it's unclear what's causing the illness but some of the seven patients also had the flu. Authorities are urging hospital staff to wear masks when caring for patients who appear to be suffering from respiratory illnesses. The Centers for Disease Control referred all questions to Alabama health officials.source : http://www.foxnews.com/health/2013/05/22/mysterious-illness-kills-2-in-southeast-alabama/

Health literature is too complex for most patients to grasp, study shows

The importance of health literacy hit home for Lisa Gualtieri when a Cambodian refugee diagnosed with cancer asked her to act as a patient advocate. She played the role of a “salty tongue,” a Cambodian expression that paints outspokenness in a positive light. But even though the patient's family was in the room when doctors took the time to answer every last question about test results and treatment options, the refugee's family would call Gualtieri hours later to review what doctors had said. A new study, published Monday in JAMA Internal Medicine, suggests one potential reason for the family's confusion: Despite good intentions, many experts may be creating educational materials that are too difficult for patients and their families to grasp. “Patients will often come to the office, and one of the first things they say to you, especially about technical information, they'll say that they've been on the Internet, and they'll quote one or two key phrases back to you,” said study author Dr. Charles Prestigiacomo. “Unfortunately, the little soundbites, while accurate, may not be complete.” Prestigiacomo and his colleagues at the University of Medicine and Dentistry of New Jersey (UMDNJ) in Newark used a number of readability scales - including “simple measure of gobbledygook (SMOG) grading” - to test how challenging materials by 16 different medical specialty societies were to read. The average reading level of the online materials by groups ranging from the American Society of Anesthesiologists to the American Psychiatric Association, fell anywhere from ninth grade to the sophomore year of college. (See one example here:.) That's far above the fourth-to-sixth grade level recommended by the American Medical Association and by a number of U.S. government agencies such as the Department of Health and Human Services. Those guidelines are based on the fact that the average American reads at 7th or 8th grade level, said Nitin Agarwal, a medical student at UMDNJ and another author of the study. “We might not be cognizant of the population reading our articles, who might need something more simple,” Agarwal said. The current study's findings agree with those of previous work by some of the same researchers looking at patient education materials in individual specialties. “Organizations often end up using jargon,” said Gualtieri, who studies health communication at Tufts University in Medford, Massachusetts, but was not involved in the new research. They end up “using the language they're accustomed to as opposed to (the language) the people they're trying to reach are accustomed to using,” she said. “You have to think about reaching people where they are,” she added. Sometimes, according to Prestigiacomo, that means using analogies. “There are only so many ways you can describe an aneurysm,” said the UMDNJ neurosurgeon, who tells patients such ballooning blood vessels are “like a blister on a tire.” “The problem is that it's not quite perfectly accurate,” he said. “But sometimes we have to realize that simplifying it to an analogy may be the best way for patients to understand it.” DROWNING IN CLICHES When it came to the quality of the writing, obstetrics and gynecology really failed to deliver. Materials in that specialty had nearly six cliches for every 50 pages, and also “contained the highest total number of indefinite article mismatches (the improper use of “a” or “an”).” “You go from region to region in the U.S., people aren't familiar with what each cliche refers to,” said Agarwal. And in a sentence that might have unintentionally demonstrated the authors' point, they report, “The proportion of passive voice sentences used throughout resources ranged from 4% in family medicine to 27% in neurological surgery.” “Concise and to the point is the way to go for this sort of stuff,” Agarwal said. Gualtieri recommended that those who produce such materials consider why people are coming to their sites, and what they're looking for. She echoed the authors' suggestion that such sites use pictures and videos. “The organizations represented should be happy that people are at their sites,” Gualtieri said. “It's high-quality, reliable information, there's a lot out there that isn't. If one of these organizations could read something like this, and say, ‘we're not doing everything we can for those who most read us,' that would be a lovely outcome from a study like this.” That's already happened. Prestigiacomo showed the results to one of the specialty groups whose patient materials were analyzed before publishing the paper, and the organization committed to rewriting them. And the Cambodian man with cancer is doing well, Gualtieri said. “The treatment was successful.”source : http://www.foxnews.com/health/2013/05/21/health-literature-is-too-complex-for-most-patients-to-grasp-study-shows/

After a decade, global AIDS program looks ahead

The decade-old law that transformed the battle against HIV and AIDS in developing countries is at a crossroads. The dream of future generations freed from epidemic is running up against an era of economic recovery and harsh budget cuts. The President's Emergency Plan for AIDS Relief grew out of an unlikely partnership between President George W. Bush and lawmakers led by the Congressional Black Caucus. It has come to represent what Washington can do when it puts politics aside - and what America can do to make the world a better place. President Barack Obama, speaking at the recent dedication of Bush's presidential library, praised the compassion Bush showed in “helping to save millions of lives and reminding people in some of the poorest corners of the globe that America cares.” House Democratic leader Nancy Pelosi said of Bush in a statement that “while many events may distinguish his presidency, his devotion to combatting the scourge of HIV/AIDS will certainly define his legacy.” The AIDS program's future, however, is uncertain. Obama has upped the stakes, speaking in his State of the Union address this year of “realizing the promise of an AIDS-free generation.” But funding for the relief plan's bilateral efforts has dipped in recent years and it's doubtful that Congress, in its current budget-cutting mood, will reverse that trend when the current five-year program expires later this year. The AIDS program is also trying to find a balance between its goals of reaching more people with its prevention and treatment programs and turning over more responsibility to the host nations where it operates. “This has been an incredible achievement,” said Rep. Barbara Lee, D-Calif., a senior Congressional Black Caucus member who played major roles both in passing the original 2003 act and its 2008 renewal that significantly increased funding for AIDS, malaria and tuberculosis treatment in Africa and other areas of the developing world. She spoke of the more than 5 million people now receiving life-saving antiretroviral treatment and 11 million pregnant women who received HIV testing and counseling last year. “But I'm worried that with any type of level-funding or cuts we'll go backward,” she said. The 2008 act more than tripled funding from the 2003 measure, approving $48 billion over five years for bilateral and global AIDS programs, malaria and tuberculosis. It also ended U.S. policy making it almost impossible for HIV-positive people to get visas to enter the country. The AIDS program was the largest commitment ever by a nation to combat a single disease internationally. According to the U.N.'s UNAIDS and the Kaiser Family Foundation, in 2011 the United States provided nearly 60 percent of all international AIDS assistance. A decade ago, almost no one in sub-Saharan Africa was receiving antiretroviral treatment. By 2008, the AIDS program had boosted that number to 1.7 million. As of last year it was 5.1 million. The State Department says the program last year also helped provide treatment to some 750,000 HIV-positive pregnant women, allowing about 230,000 infants to be born HIV-free, supported 2 million male circumcisions and directly supported HIV testing and counseling for 46.5 million. “This is a remarkable story that the American people should know about,” Kimberly Scott of the Institute of Medicine, which recently completed an evaluation of the AIDS program, said at a forum sponsored by the Kaiser Family Foundation and the CSIS Global Health Policy Center. According to UNAIDS, the number of people living with HIV has leveled off, standing at about 34 million at the end of 2011. New infections that year reached 2.5 million, down 20 percent from 2001. AIDS-related deaths were 1.7 million, down from 2.3 million in 2005. Jennifer Kates, director of global health and HIV policy at Kaiser, said most countries where the program operates have yet to reach the “tipping point,” where new infections occurring in a year are less than the increase in people receiving treatment. Among the success stories were Ethiopia, where the 40,000 going on treatment in 2011 was almost four times the new infections. Still with a long way to go was Nigeria, which that year had 270,000 new HIV infections and a 57,000 increase in those getting treatment. Chris Collins, director of public policy at amfAR, The Foundation for AIDS Research, also warned of potential repercussions as the AIDS program shifts from being an emergency response to the AIDS epidemic to a more supportive role for country-based health programs. “The countries themselves largely are avoiding the important role that key populations play in epidemics,” he said, referring to gay men, those injecting drugs and sex workers. These groups face discrimination and criminal charges in many cases, and 90 percent of the money to help them now comes from external sources. Collins also spoke of the “huge mismatch” between the positive science and rhetoric on fighting AIDS and the money available. Since 2009 the funding for bilateral and global HIV and AIDS programs has largely stalled. Kaiser's Kates said that while there's still bipartisan support for the AIDS program in Congress, “the big question is will the financing be there to reach the goals” of treating more people and advancing toward that AIDS-free generation. “The challenge right now is that the global economic climate is different, the U.S. climate is different, but the need is still great.”source : http://www.foxnews.com/health/2013/05/21/after-decade-global-aids-program-looks-ahead/

Victims claim Marines failed to safeguard water supply

CAMP LEJEUNE, N.C. – & A simple test could have alerted officials that the drinking water at Camp Lejeune was contaminated, long before authorities determined that as many as a million Marines and their families were exposed to a witch's brew of cancer-causing chemicals. But no one responsible for the lab at the base can recall that the procedure -- mandated by the Navy -- was ever conducted. The U.S. Marine Corps maintains that the carbon chloroform extract (CCE) test would not have uncovered the carcinogens that fouled the southeastern North Carolina base's water system from at least the mid-1950s until wells were capped in the mid-1980s. But experts say even this “relatively primitive” test -- required by Navy health directives as early as 1963 -- would have told officials that something was terribly wrong beneath Lejeune's sandy soil. A just-released study from the federal Agency for Toxic Substances and Disease Registry cited a February 1985 level for trichloroethylene of 18,900 parts per billion in one Lejeune drinking water well -- nearly 4,000 times today's maximum allowed limit of 5 ppb. Given those kinds of numbers, environmental engineer Marco Kaltofen said even a testing method as inadequate as CCE should have raised some red flags with a “careful analyst.” “That's knock-your-socks-off level -- even back then,” said Kaltofen, who worked on the infamous Love Canal case in upstate New York, where drums of buried chemical waste leaked toxins into a local water system. “You could have smelled it.” Biochemist Michael Hargett agrees that CCE, while imperfect, would have been enough to prompt more specific testing in what is now recognized as the worst documented case of drinking-water contamination in the nation's history. “I consider it disingenuous of the Corps to say, `Well, it wouldn't have meant anything,”' said Hargett, co-owner of the private lab that tried to sound the alarm about the contamination in 1982. “The levels of chlorinated solvent that we discovered ... they would have gotten something that said, `Whoops. I've got a problem.' They didn't do that.” Trichloroethylene (TCE), tetrachloroethylene (PCE), benzene and other toxic chemicals leeched into ground water from a poorly maintained fuel depot and indiscriminate dumping on the base, as well as from an off-base dry cleaner. Nearly three decades after the first drinking-water wells were closed, victims are still awaiting a final federal health assessment -- the original 1997 report having been withdrawn because faulty or incomplete data. Results of a long-delayed study on birth defects and childhood cancers were only submitted for publication in late April. Many former Lejeune Marines and family members who lived there believe the Corps still has not come clean about the situation, and the question of whether these tests were conducted is emblematic of the depth of that mistrust. Marine Corps officials have repeatedly said that federal environmental regulations for these cancer-causing chemicals were not finalized under the Safe Drinking Water Act until 1989 -- about four years after the contaminated wells had been identified and taken out of service. But victims who have scoured decades-old documents say the military's own health standards should have raised red flags long before. In 1963, the Navy's Bureau of Medicine and Surgery issued “The Manual of Naval Preventive Medicine.” Chapter 5 is titled “Water Supply Ashore.” “The water supply should be obtained from the most desirable sources which is feasible, and effort should be made to prevent or control pollution of the source,” it reads. At the time, the Defense Department adopted water quality standards set by the U.S. Public Health Service. To measure that quality, the Navy manual identified CCE “as a technically practical procedure which will afford a large measure of protection against the presence of undetected toxic materials in finished drinking water.” Also referred to as the “oil and grease test,” CCE was intended to protect against an “unwarranted dosage of the water consumer with ill-defined chemicals,” according to the Navy manual. The CCE standard set in 1963 was 200 ppb. In 1972, the Navy further tightened it to no more than 150 ppb. In response to a request from The Associated Press, Capt. Kendra Motz said the Marines could produce no copies of CCE test results for Lejeune, despite searching for “many hours.” “Some documents that might be relevant to your question may no longer be maintained by the Marine Corps or the Department of the Navy in accordance with records management policies,” she wrote in an email. “The absence of records 50 years later does not necessarily mean action was not taken.” But the two men who oversaw the base lab told the AP they were not even familiar with the procedure. “A what?” asked Julian Wooten, who was head of the Lejeune environmental section during the 1970s, when asked if his staff had ever performed the CCE test. “I never saw anything, unless the (Navy's) preventive medicine people were doing some. I don't have any knowledge of that kind of operation or that kind of testing being done. Not back then.” “I have no knowledge of it,” said Danny Sharpe, who succeeded Wooten as section chief and was in charge when the first drinking water wells were shut down in the mid-1980s. “I don't remember that at all.” Wooten was an ecologist, and Sharpe's background is in forestry and soil conservation. But Elizabeth Betz, the supervisory chemist at Lejeune from 1979 to 1995, was also at a loss when asked about the CCE testing. “I do not remember any such test being requested nor do I remember seeing any such test results,” Betz, who later worked for the U.S. Environmental Protection Agency's national exposure branch at Research Triangle Park outside Raleigh, wrote in a recent e-mail. Hargett, the former co-owner of Grainger Laboratories in Raleigh, said he never saw any evidence that the base was testing and treating for anything beyond e coli and other bacteria. “That was a state regulation ... that they had to maintain a sanitary water supply,” he said. “And they did a good job at that.” Motz, the Marine spokeswoman, told the AP that the method called for in the manual would not have detected the toxins at issue in the Camp Lejeune case. “The CCE method includes a drying step and a distillation (evaporation) step where chloroform is completely evaporated,” she wrote in an email. These volatile organic compounds, “by their chemical nature, would evaporate readily as well,” she wrote. ATSDR contacted the EPA about the “utility” of such testing and concluded it would be of no value in detecting TCE, PCE, or benzene, Deputy Director Tom Sinks wrote in an email to members of a community assistance panel on Lejeune. “It is doubtful that the weight of their residue would be detectable when subjected to this method,” Sinks wrote. Kaltofen, a professor at Worcester Polytechnic Institute in Massachusetts, acknowledged that CCE is “a relatively primitive test.” But in addition to the water's odor, Kaltofen said, “there are some things that a careful analyst would easily have noticed.” Hargett agreed. “It would have prompted you to simply say, `Wow. There is something here. Let's do some additional work,”' he told the AP. Any “reputable chemist ... would have raised their hands to the person responsible and said, `Guys. You ought to look at this. There's more here.”' The Marines have said such high readings were merely spikes. But Kaltofen countered that, “You can't get that level even once without having a very serious problem ... It's the worst case.” In a recent interview, Wooten told the AP that he knew something was wrong with the water as early as the 1960s, when he worked in the maintenance department. “I was usually the first person in in the big building that we worked in,” he said. “And I'd cut the water on and let it run, just go and flush the commodes and cut the water on and let it run for several minutes before I'd attempt to make coffee.” Wooten said he made repeated budget requests for additional equipment and lab workers. But as Betz told a federal fact-finding group, “the lab was very low on the priority list at the base.” She said her group -- the Natural Resources and Environmental Affairs Department -- was “like the `red headed stepchild.”' Even a series of increasingly urgent reports from an Army lab at Fort McPherson, Ga., beginning in late 1980, failed to prompt any real action. “WATER HIGHLY CONTAMINATED WITH OTHER CHLORINATED HYDROCARBONS (SOLVENTS!)” cautioned one memo from the Army lab in early 1981. Because the base water system drew on a rotating basis from a number of different wells, subsequent tests showed no problems, and officials chalked these “interferences” up to flukes. One base employee told the fact-finding group that in 1980, “they simply did not have the money nor capacity” to test every drinking-water well on the base. “This type of money would have cost well over $100,000, and their entire operating budget was $100,000,” the employee said, according to a heavily redacted summary obtained by the AP from the Department of Justice through the Freedom of Information Act. “However, they did not do the well testing because they did not think they needed to.” So, from late 1980 through the summer of 1982, the former employee told investigators, “this issue simply laid there. No attempts were made to identify ground contamination” at Hadnot Point or Tarawa Terrace, where most of the enlisted men and their families lived. It wasn't until a letter from Grainger in August 1982 reported TCE levels of 1,400 ppb that any kind of widespread testing began. Though the EPA did not yet enforce a limit for TCE at the time, the chemical had long been known to cause serious health problems. “That is when the light bulb went off,” Sharpe told federal investigators in a 2004 interview, obtained by the AP. “That is when we connected the tests of the 1980, 1981, and 1982 time period where traces of solvents were detected to this finding.” Still, it was not until the final weeks of 1984 that the first wells were closed down. Between the receipt of that 1982 letter and the well closures, the employee told the fact-finding group, “they simply dropped the ball.” Each year of delay meant an additional 10,000 people may have been exposed, according to Marine estimates. Municipal utilities around the country were using far more sophisticated tests to detect much lower contaminate levels, said Kaltofen, while the people at Camp Lejeune were doing “the bare minimum. And it wasn't enough.” Last year, President Obama signed the Camp Lejeune Veterans and Family Act to provide medical care and screening for Marines and their families, but not civilians, exposed between 1957 and 1987 -- although preliminary results from water modeling suggest that date be pushed back at least another four years. The law covers 15 diseases or conditions, including female infertility, miscarriage, leukemia, multiple myeloma, as well as bladder, breast, esophageal, kidney and lung cancer. Jerry Ensminger, a former drill sergeant, blames the water for the leukemia that killed his 9-year-old daughter, Janey, in 1985. He and Michael Partain -- a Marine's son who is one of at least seven dozen men with Lejeune ties diagnosed with a rare form of breast cancer -- have scoured the records, and he thinks the Corps has yet to accept responsibility for its role in this tragedy. “If I hadn't dug in my heels,” Ensminger said, “this damned issue would have been dead and buried along with my child and everybody else's.”source : http://www.foxnews.com/health/2013/05/18/victims-claim-marines-failed-to-safeguard-water-supply/

What you need to know about new PSA screening guidelines

Recently, the American Urological Association (AUA) announced new guidelines for prostate specific antigen (PSA) testing.  These guidelines were designed to help urologists, and ultimately patients, reduce prostate cancer mortality by making informed screening decisions.  These recommendations were based on comprehensive literature reviews and the strength of the existing evidence.   Here is what you need to know: • The AUA recommends against screening in men under age 40.  Such blanket recommendations can increase the risk of younger men being overlooked and potentially resulting in worse disease later in life. Men under 40 need to be educated about prostate cancer and given a clear understanding of their individual risk factors.   Obesity/excess weight, a family history of prostate cancer, and African American race are the driving risk factors of this disease. • The AUA recommends against routine screening in men of average risk aged 40 to 54 years old.  Early diagnosis and treatment are the two most important factors to successfully eliminating prostate cancer. • The AUA strongly recommends careful consideration of the pros and cons of screening for men between the ages of 55 and 69.  The risk of prostate cancer increases significantly by age 65; so it’s wise for men in this age bracket to be screened. These men have the greatest opportunity for early detection and treatment to eliminate their prostate cancer with optimal quality of life. • The AUA suggests screening for prostate cancer every two years rather than annually. PSA is not a perfect test.  Prostate cancer can be an indolent cancer, taking many years to decades before it causes problems or it can behave in a highly aggressive manner. PSA is not able to differentiate these two cases. However, by tracking PSA velocity and density we can more accurately predict one’s risk of cancer. • The AUA recommends against PSA screening in men over age 70 with a life expectancy less than 10-15 years.  Now that such a large percentage of Americans live well into their 80s, prostate cancer screening should be part of overall wellness monitoring for these men. Prostate cancer remains the second leading cause of cancer death in men, killing approximately 34,000 men each year.  Since the widespread adoption of PSA screening in the early 90s, there has been a 39 percent reduction in prostate cancer mortality rates; so there is no doubt that PSA screening is successful – when used correctly.   Speak with your doctor about your individual risk factors for prostate cancer and your treatment goals.  Through comprehensive education about prostate cancer testing, diagnosis, and treatment options, American men can make well-informed decisions about what’s best for them. Dr. David B. Samadi is the Vice Chairman of the Department of Urology and Chief of Robotics and Minimally Invasive Surgery at the Mount Sinai School of Medicine in New York City. He is a board-certified urologist, specializing in the diagnosis and treatment of urological disease, with a focus on robotic prostate cancer treatments. To learn more please visit his websites RoboticOncology.com and SMART-surgery.com. Find Dr. Samadi on Facebook.Dr. David B. Samadi is the Vice Chairman of the Department of Urology and Chief of Robotics and Minimally Invasive Surgery at the Mount Sinai School of Medicine in New York City. He is a board-certified urologist, specializing in the diagnosis and treatment of urological disease, with a focus on robotic prostate cancer treatments. To learn more please visit his websites RoboticOncology.com and SMART-surgery.com. Find Dr. Samadi on Facebook.source : http://www.foxnews.com/health/2013/05/17/what-need-to-know-about-new-psa-screening-guidelines/

Brain makes call on which ear is used for cell phone

The study — to appear online in JAMA Otolaryngology-Head & Neck Surgery — shows a strong correlation between brain dominance and the ear used to listen to a cell phone. More than 70% of participants held their cell phone up to the ear on the same side as their dominant hand, the study finds. Left-brain dominant people — who account for about 95% of the population and have their speech and language center located on the left side of the brain — are more likely to use their right hand for writing and other everyday tasks. Likewise, the Henry Ford study reveals most left-brain dominant people also use the phone in their right ear, despite there being no perceived difference in their hearing in the left or right ear…

India developing cheap vaccine against major cause of diarrhea deaths in kids

The Indian government announced Tuesday the development of a new low-cost vaccine proven effective against a diarrhea-causing virus that is one of the leading causes of childhood deaths across the developing world. The Indian manufacturer of the new rotavirus vaccine pledged to sell it for $1 a dose, a significant discount from the cost of the current vaccines on the market. That reduced price would make it far easier for poor countries to vaccinate their children against the deadly virus, health experts said. Rotavirus, spread through contaminated hands and surfaces, kills about half a million children across the world each year, 100,000 of them in India. At a conference Tuesday, the government announced that Phase III trials of Rotavac proved that it was safe as well as effective. The clinical trial of 6,799 infants at three sites in India showed the vaccine reduced severe cases of diarrhea caused by rotavirus by 56 percent during the first year of life. “The clinical results indicate that the vaccine, if licensed, could save the lives of thousands of children each year in India,” said Dr. K. Vijay Raghavan, the secretary of the Department of Biotechnology. The vaccine still needs to be licensed before it can be distributed in India and would require further approval by the World Health Organization before it could be distributed globally. Two other vaccines have proven effective against rotavirus, but they are significantly more expensive. The GAVI Alliance, which works to deliver vaccines to the world’s poor, negotiated a significant discount last year with GlaxoSmithKline and Merck, obtaining the rotavirus vaccines from those pharmaceutical companies for $2.50 a dose. The alliance has programs for delivering those vaccines in 14 countries and plans to expand them to 30 countries. Dr. Seth Berkley, the GAVI Alliance’s CEO, said the announcement Tuesday was “a big deal.” “The cheaper the price the more children you can immunize,” he said, adding that it will still take some time before the vaccine is approved for use. In addition, having a third manufacturer for the vaccines would ease supply shortages and could drive down the costs charged by the other manufacturers, he said. “That would make a big difference in terms of changing the marketplace,” he said. Diarrhea is the second leading cause of death among young children in the world after pneumonia. A study of 22,568 children at sites in seven African and south Asian countries that was published Monday in the medical journal The Lancet showed that rotavirus was the leading cause of moderate to severe diarrhea in children under the age of two. The new vaccine was developed from a weakened strain of the virus taken from a child hospitalized in New Delhi more than a quarter century ago. It was the result of a broad global partnership that included the government, the Indian company Bharat Biotech, the Bill and Melinda Gates Foundation and the U.S. Centers for Disease Control and Prevention, among many others. Those involved said the broad cooperation reduced research costs for the manufacturer and helped keep the vaccine inexpensive. “This public-private partnership is an exemplary model of how to develop affordable technologies to save lives,” Bill Gates, co-chair of the Gates Foundation, said in a statement.source : http://www.foxnews.com/health/2013/05/15/india-developing-cheap-vaccine-against-major-cause-diarrhea-deaths-in-kids/

Tumor-activated protein promotes cancer spread

The findings are published in this week’s online Early Edition of the Proceedings of the National Academy of Sciences. Roughly 90 percent of all cancer deaths are due to metastasis — the disease spreading from the original tumor site to multiple, distant tissues and finally overwhelming the patient’s body. Lymph vessels are often the path of transmission, with circulating tumor cells lodging in the lymph nodes — organs distributed throughout the body that act as immune system garrisons and traps for pathogens and foreign particles. The researchers, led by principal investigator Judith A. …

Four new genetic risk factors for testicular cancer identified

The discovery of these genetic variations — chromosomal "typos," so to speak — could ultimately help researchers better understand which men are at high risk and allow for early detection or prevention of the disease. "As we continue to cast a wider net, we identify additional genetic risk factors, which point to new mechanisms for disease," said Katherine L. Nathanson, MD, associate professor in the division of Translational Medicine and Human Genetics within the department of Medicine. …

Mapping the embryonic epigenome: How genes are turned on and off during early human development

After an egg has been fertilized, it divides repeatedly to give rise to every cell in the human body — from the patrolling immune cell to the pulsing neuron. Each functionally distinct generation of cells subsequently differentiates itself from its predecessors in the developing embryo by expressing only a selection of its full complement of genes, while actively suppressing others…