"Cells normally monitor the availability of nutrients and will slow down or accelerate their growth and division accordingly. A key monitor of nutrients is a protein called the Target of Rapamycin (TOR), but we do not know the details of how this protein feeds signals downstream to control growth" says Dr. Stephen Michnick, senior author and a University of Montreal biochemistry professor…
Officials investigating a cluster of mysterious illnesses in Alabama have so far found only cold and flu viruses. In tests on seven of the nine patients, the Centers for Disease Control and Prevention found no sign that the illnesses were caused by any single germ, CDC spokeswoman Sharon Hoskins said in an email. Meanwhile, Alabama officials said they had added two more cases to the cluster, which included two earlier deaths. Seven of the cases were reported last week, including the deaths. The two new illnesses were reported this week. Most of the nine were treated at Southeast Alabama Medical Center in Dothan, but one was seen at a hospital in Crenshaw County. Health officials have described the patients as ranging in age from 20 to more than 80. The nine people suffered a flu-like illness with symptoms like fever, cough and shortness of breath. Mysterious illnesses are always unnerving, but the cluster report came at a particularly sensitive time. Health officials have been monitoring two deadly new illnesses that recently surfaced in different parts of the world — one a deadly form of bird flu that has appeared in China, the other a SARS-like coronavirus that seems to have originated in the Middle East. The bird flu has caused 131 illnesses and 32 deaths since the beginning of the year, according to the World Health Organization. The SARS-like virus (called MERS) has been identified as the cause of 44 illnesses, including 22 deaths, the WHO said. Neither seems to be highly contagious so far, and neither illness has been reported in the United States. But in a world of daily international air travel, it's always possible that a concerning new germ will hitchhike on an infected globetrotter and enter this country. The CDC tested the Alabama patients for MERS, for different forms of flu and for more than a dozen other illnesses, the agency spokeswoman said.source : http://www.foxnews.com/health/2013/05/23/mystery-illness-in-alabama-mostly-colds-and-flu-tests-show/
The American Cancer Society - one of the nation's best known and influential health advocacy groups - is 100 years old this week. Back in 1913 when it was formed, cancer was a lesser threat for most Americans. The biggest killers then were flu, pneumonia, tuberculosis, and stomach bugs. At a time when average life expectancy was 47, few lived long enough to get cancer. But 15 doctors and businessmen in New York City thought cancer deserved serious attention, so they founded the American Society for the Control of Cancer. The modern name would come 31 years later. The cancer society's rise coincided with the taming of infectious diseases and lengthening life spans. “Cancer is a disease of aging, so as people live longer there will be more cancer,” explained Dr. Michael Kastan, executive director of Duke University's Cancer Institute. Cancer became the nation's No. 2 killer in 1938, a ranking it has held ever since. It also became perhaps the most feared disease - the patient's own cells growing out of control, responding only to brutal treatments: surgery, radiation and poisonous chemicals. The cancer society is credited with being the largest and most visible proponent of research funding, prevention and programs to help house and educate cancer patients. Last year, the organization had revenues of about $925 million. It employs 6,000 and has 3 million volunteers, calling itself the largest voluntary health organization in the nation. “The American Cancer Society really is in a league of its own,” Kastan said. The rate of new cancer cases has been trending downward ever so slightly. Some historical highlights: 1913 - The American Society for the Control of Cancer is founded in New York City. 1944 - The organization is renamed the American Cancer Society. The change is spurred by Mary Lasker, the wife of advertising mogul Albert Lasker. 1946 - A research program is launched, built on $1 million raised by Mary Lasker. A year later, Dr. Sidney Farber of Boston announces the first successful chemotherapy treatment. 1948 - The cancer society pushes the Pap test, which has been credited with driving a 70 percent decline in uterine and cervical cancer. 1964 - Prodded by the cancer society and other groups, U.S. Surgeon General Luther Terry issues a report irrefutably linking smoking to cancer. 1971 - The cancer society helps lead passage of the National Cancer Act to ramp up research money. President Nixon declares a national “war on cancer,” which becomes an extended effort derided by some as a “medical Vietnam.” 1976 - The cancer society suggests women 40 and older consider a mammogram if their mother or sisters had breast cancer. 1976 - The cancer society hosts a California event to encourage smokers to quit for the day. A year later, the annual Great American Smokeout is launched nationally. 1988 - Atlanta becomes headquarters for the society. 1997 - The cancer society recommends yearly mammograms for women over 40. 2000 - Dr. Brian Druker of Oregon reports the first success with “targeted” cancer therapy. 2003 - The cancer society stops recommending monthly breast self-exams. But it continues to urge annual mammograms for most women over 40, even after a government task force says most don't need screening until 50. 2012 - The cancer society reports the rate of new cancer cases has been inching down by about half a percent each year since 1999.source : http://www.foxnews.com/health/2013/05/22/american-cancer-society-turns-100-as-us-cancer-rates-fall/
Teens who have a classmate die of suicide are more likely to consider taking, or attempt to take, their own lives, according to a new study. The idea that suicide might be “contagious” has been around for centuries, senior author Dr. Ian Colman, who studies mental health at the University of Ottawa, said. Past studies supported the idea, but none had looked at such a large body of students, he said. “There were a lot of surprising things about this study, we were surprised that the effect lasted so long and just how strong it was,” Colman said. Colman and his colleagues used data from a long-running national survey of more than 8,000 Canadian kids aged 12 to 17 years old. Students were asked about suicides of schoolmates, friends and their own thoughts of suicide, and researchers checked in with the kids two years later. By the age of 17, one in four kids had a schoolmate who had committed suicide, and one in five knew the deceased personally, according to results published in the Canadian Medical Association Journal. For the 12- and 13-year-old adolescents exposed to a schoolmate's suicide, 15 percent reported thinking seriously about killing themselves and seven percent actually made an attempt, compared to 3 percent and 2 percent of unexposed kids, respectively. The effect persisted even if the schoolmate had died more than a year earlier. Results were similar for 14- and 15-year-olds and 16- and 17-year-olds, but older kids who had not been exposed to suicide were more likely to have thought of or attempted it. “For 12- and 13-year olds, they were approximately five times more likely to report thinking about suicide,” Colman said. “That's a huge effect.” They found no difference between kids who personally knew the deceased and those who didn't. In the U.S., about 4,600 people aged 10 to 25 years old commit suicide, according to the Centers for Disease Control. NEW POLICIES? Based on the results, school “post-vention” programs should encompass the whole school, not just those closest to the deceased, and should perhaps revisit parts of the intervention months and years down the line, Colman said. It may make sense that kids who knew the deceased and those who didn't seemed to have no difference in risk, Frank Zenere, a school psychologist at the Miami-Dade County public school system, said. “Sometimes the closest friends are not the ones that are most likely to harm themselves because they're so up close and aware of the painful fallout with the family of the deceased, which can actually be a protective factor,” Zenere said. The younger kids tend to be most vulnerable and impressionable, he said. “There's a lot more drama in middle school grade levels, they tend to have much more of an emotional outpouring, early teens versus late teens,” he said. Though the current study indicates the effect persists for at least two years, Zenere believes it may go on even longer. Some school districts may rewrite policies and procedures in light of these results, but those at most, including his own, are probably already designed to take relevant factors into account. “It's really important for parents to talk to their kids about mental health and to help them get professional help if needed,” Colman said.source : http://www.foxnews.com/health/2013/05/21/schoolmates-suicide-victims-at-higher-risk/
When Wes Schlauch, of Breinigsville, PA, was 16 years old, he suffered a stroke that paralyzed the entire right side of his body. Miraculously, three years later, Wes is not only walking and talking – he’s even sending text messages, attending college and going on fishing trips with friends. Wes’ positive attitude, devotion to rehabilitation and strong support system has had much to do with his success. But Wes has also benefitted tremendously from a cutting-edge technology that is revolutionizing therapies for patients suffering from brain injuries and neurodegenerative diseases: a new treatment known as functional electrical stimulation (FES). FES has been pioneered by companies like Bioness Inc., based in Valencia, CA., which created the devices that Wes uses. The devices – which Wes wears on both his right hand and leg – use electricity to stimulate the damaged portions of his brain and the neural connections between the brain and muscles. “The idea is that by using the electrical stimulation to make the muscle fire, his brain will retrain and relearn, and his muscles will fire more automatically without it in the long term,” Jolene Hammer, a physical therapist at Lehigh Valley Hospital in Bethlehem, PA., who works with Wes, told FoxNews.com. FOUR IN 100,000 Strokes are incredibly rare among children and teenagers like Wes. “From after the newborn period through age 18, the incidence (of stroke) that we estimate is about four in 100,000 children per year,” Dr. Rebecca Ichord, director of the pediatric stroke program at The Children’s Hospital of Philadelphia, who treated Wes, told FoxNews.com. According to Ichord, Wes’ stroke was likely triggered after he experienced whiplash while playing hockey. Doctors believe that one of the arteries in Wes’ neck twisted and dissected, causing the walls of the artery to separate. This caused a blockage in Wes’ blood flow that led to the formation of a clot – resulting in a stroke. Wes’ stroke was particularly devastating because it occurred in his baseline artery, which facilitates blood flow to critical parts of the brain. “(His) was one of the most severe types of strokes; when you block the baseline artery, you block critical parts of brain systems that control all elements of function,” Ichord said. “The mortality is relatively higher than in other types of stroke and long term handicap can be devastating.” Luckily, Wes was able to receive a clot-dissolving therapy within eight hours of his stroke, which restored blood flow to the injured part of his brain. However, Wes still had a long journey ahead of him. The right side of Wes’ body was paralyzed – a condition called hemiparesis. “I remember lying in the hospital bed and looking up at the ceiling, because that’s all I could do,” Wes told FoxNews.com. “My respiratory therapist told me to visualize myself getting better so I just visualized myself getting out of that situation.” Eventually, Wes stabilized and was moved to a rehabilitation facility where he had to relearn basic daily tasks, like dressing himself and eating – all the while confined to a wheelchair. THE RECOVERY PROCESS Fortunately, Wes didn’t stay in his wheelchair for long.  He soon progressed to a walker and then to a cane. As Wes regained his strength, he was able to begin FES treatments, with the help of his rehabilitation team.   To regain the use of his right hand, Wes eventually began using the Bioness NESS H200® Hand Rehabilitation System – an external device that Wes wears on his hand and arm. “That’s helped me be able to be more dexterous with my movements and has overall helped my hand big time,” Wes said. “It used to be that my hand was in a fist, and I wasn’t able to use it at all. I got the H200 device and I was able to use my hand nicely.” “I’ve even been known to text with my right hand,” Wes added. Later, Wes progressed to the NESS L300™ Foot Drop System, which allowed his foot to move more freely. “As he’s been using it, I see that he’s now able to start to actively move those muscles without it that he wasn’t before…Now, he can lift his foot and be aware of it and pull it up on his own,” Hammer said. “He has gotten to be able to lift his toe up and to be able to activate his hamstring.  Just last week, Wes took home a new device – the L300 Plus – which he will wear on his thigh to stimulate his hamstring. Wes will use this in conjunction with the L300 in order to gain further control over his leg, bolstering his ability to walk and even maneuver stairs. Though Wes gets fatigued easily (especially when using the devices), he is building up his tolerance and strength, and he eventually hopes to be able to wear both the L300 and L300 Plus for full days. “It’s helped my walking a ton and being able to walk around the community is a lot better for me as opposed to just being in a wheelchair like I was before. Now I’m on a cane. It’s helped me a lot,” Wes said. Wes’ doctors hope that technology like the Bioness devices will eventually help repair the damaged parts of Wes’ brain to some extent. “I think it’s a cutting edge way to start to work on retraining the muscle and hopefully to play into neuroplasticity, to activate the brain to make new connections and to activate these muscles,” Hammer said. ‘AN EXTRAORDINARY YOUNG MAN’ Wes continues to make extraordinary advances in his treatment and personal life – even making the dean’s list at college. “His speech is also a little affected, but he can still communicate,” Ichord said. “And his cognitive learning abilities, personality and sense of humor (were) all preserved; the thinking part is doing well and was never directly affected.” Wes credits his experience as a hockey player for giving him his strong work ethic.   “I work hard, I always did – back from when I was 16 on. I worked as hard as I could and…I really want to get back on the ice. That’s my main motivating factor,” Wes said. Wes continues to impress his physical therapists and doctors every day, and Hammer said she has high hopes for Wes’ future progress.   “I’ve been a therapist for a long time and he’s an extraordinary young man – one of the most motivated people I’ve met. If every patient worked as hard as him, I’d be out of a job,” Hammer said.source : http://www.foxnews.com/health/2013/05/20/electric-stimulation-treatments-help-young-stroke-victim/
For many women, the extra calories that are vital for a healthy pregnancy often become a green light to indulge and give into cravings. In fact, more than 30 percent of women who have a normal weight before becoming pregnant gain more than the recommended amount during pregnancy, according to the Centers of Disease Control and Prevention’s Pregnancy Risk Assessment Monitoring System. If you’re overweight or obese before getting pregnant, or you gain too much weight during pregnancy, you and your baby’s health could be compromised. For starters, there’s an increased risk of high blood pressure, gestational diabetes and preeclampsia. There’s also a greater chance that you could have a miscarriage, a stillborn baby, deliver early or be required to have a cesarean section. Your baby could also develop birth defects and detecting them with an ultrasound can be tricky if you’re obese, according to Dr. Alyssa Dweck, a board-certified obstetrician and gynecologist and co-author of V is for Vagina. During labor and delivery, there’s also a higher chance for blood clots, C-section infection, and difficulty administering anesthesia. You might also have a larger baby, and studies show overweight women also have problems breastfeeding. Plus, losing weight after delivery could be tough too. Several rat studies also indicate that babies born to overweight moms might actually have permanent changes in their brain structures and genetic preferences that could put them at risk for cardiovascular disease, high blood pressure, and diabetes. “It is possible that we’re creating a generation of kids who are more likely to be obese, and as they grow up and have children, it creates more and more of a genetic problem,” said Melinda Johnson, a registered dietitian and spokesperson for the Academy of Nutrition and Dietetics. Babies born to overweight mothers are also more likely to be overweight themselves, but it’s not clear if it’s because they have the same eating habits as their moms or if it’s just plain genetics, according to Johnson. Regardless, “pregnancy is a great time for future mothers to start learning better habits, because we definitely know those habits play a huge role in the health of their children,” she said. If you’re planning to get pregnant or you already are, find out what you can do to have a healthy weight.   Know the guidelines Even if you’re already overweight, weight loss should never be your goal during pregnancy, according to Dweck.  Instead, follow the Institute of Medicine’s guidelines for pregnancy weight gain, which are based on your body mass index (BMI). So if your BMI is normal, aim to gain 25 to 35 pounds; if you’re overweight stay within 15 to 25 pounds, and if you’re obese, 11 to 20 pounds. Take your vitamins To make sure you’re getting the right amount of nutrients, look for a prenatal vitamin with 1 milligram of folic acid, iron and docosahexaenoic acid (DHA). A good prenatal should also have 1200 milligrams of calcium and 600 to 1,000 milligrams of vitamin D. Eat a balanced diet It’s important to eat regular meals throughout the day to keep your blood sugar steady and your energy levels up. Johnson recommended eating every two to four hours depending on how hungry you are.  It’s OK to give into your cravings, but try to put the focus on eating lots of fruits and vegetables, whole grains, lean proteins, and low-fat dairy. Instead of eating foods loaded with saturated fats, opt for those with heart healthy fats like salmon, avocado, nuts and seeds. Drink plenty of water and nix soda, juice and sugary drinks. “Those are empty calories; they’re never going to make you feel full,” Dweck said. Talk to an expert If you’re worried about your weight or your diet, talk to your doctor or a registered dietitian about nutrition and exercise – ideally before you get pregnant.  Pregnancy is not the time to start an exercise program, Dweck said. Don’t look at the scale Is the number on the scale creeping higher every week despite your best efforts? Don’t fret, said Johnson, who noted that your weight doesn’t matter if you’re making healthy choices, paying attention to portion sizes and exercising. “If women follow that advice, they can save themselves a lot of stress,” she said.Julie Revelant is a freelance writer specializing in parenting, health, food and women's issues and a mom. Learn more about Julie at revelantwriting.com.source : http://www.foxnews.com/health/2013/05/19/how-not-to-gain-too-much-pregnancy-weight/
The Indian government announced Tuesday the development of a new low-cost vaccine proven effective against a diarrhea-causing virus that is one of the leading causes of childhood deaths across the developing world. The Indian manufacturer of the new rotavirus vaccine pledged to sell it for $1 a dose, a significant discount from the cost of the current vaccines on the market. That reduced price would make it far easier for poor countries to vaccinate their children against the deadly virus, health experts said. Rotavirus, spread through contaminated hands and surfaces, kills about half a million children across the world each year, 100,000 of them in India. At a conference Tuesday, the government announced that Phase III trials of Rotavac proved that it was safe as well as effective. The clinical trial of 6,799 infants at three sites in India showed the vaccine reduced severe cases of diarrhea caused by rotavirus by 56 percent during the first year of life. “The clinical results indicate that the vaccine, if licensed, could save the lives of thousands of children each year in India,” said Dr. K. Vijay Raghavan, the secretary of the Department of Biotechnology. The vaccine still needs to be licensed before it can be distributed in India and would require further approval by the World Health Organization before it could be distributed globally. Two other vaccines have proven effective against rotavirus, but they are significantly more expensive. The GAVI Alliance, which works to deliver vaccines to the world’s poor, negotiated a significant discount last year with GlaxoSmithKline and Merck, obtaining the rotavirus vaccines from those pharmaceutical companies for $2.50 a dose. The alliance has programs for delivering those vaccines in 14 countries and plans to expand them to 30 countries. Dr. Seth Berkley, the GAVI Alliance’s CEO, said the announcement Tuesday was “a big deal.” “The cheaper the price the more children you can immunize,” he said, adding that it will still take some time before the vaccine is approved for use. In addition, having a third manufacturer for the vaccines would ease supply shortages and could drive down the costs charged by the other manufacturers, he said. “That would make a big difference in terms of changing the marketplace,” he said. Diarrhea is the second leading cause of death among young children in the world after pneumonia. A study of 22,568 children at sites in seven African and south Asian countries that was published Monday in the medical journal The Lancet showed that rotavirus was the leading cause of moderate to severe diarrhea in children under the age of two. The new vaccine was developed from a weakened strain of the virus taken from a child hospitalized in New Delhi more than a quarter century ago. It was the result of a broad global partnership that included the government, the Indian company Bharat Biotech, the Bill and Melinda Gates Foundation and the U.S. Centers for Disease Control and Prevention, among many others. Those involved said the broad cooperation reduced research costs for the manufacturer and helped keep the vaccine inexpensive. “This public-private partnership is an exemplary model of how to develop affordable technologies to save lives,” Bill Gates, co-chair of the Gates Foundation, said in a statement.source : http://www.foxnews.com/health/2013/05/15/india-developing-cheap-vaccine-against-major-cause-diarrhea-deaths-in-kids/
U.S. health officials say last year was the worst ever for West Nile virus deaths. The final tally reported Monday was 286 deaths - or two more than the record set in 2002. But there were far fewer illnesses overall, and fewer serious cases than in previous years. The Centers for Disease Control and Prevention had predicted it would be a bad year because of weather conditions that promote breeding of the mosquitoes that spread the virus to people. The CDC report Monday showed Texas had nearly a third of the serious cases, and about a third of the deaths. West Nile virus was first diagnosed in Uganda in 1937, but no cases were reported in the U.S. until 1999 in New York. It gradually spread to the West Coast.source : http://www.foxnews.com/health/2013/05/14/deaths-from-west-nile-virus-hit-record-last-year/
Teenagers who text while driving are also more likely to engage in other risky activities, such as riding with an intoxicated driver or not wearing a seatbelt, a new study suggests. Researchers from the U.S. Centers for Disease Control and Prevention (CDC) found four in every nine high school students had sent or received texts while driving in the past month. “Considering it's against the law for teens to be texting while driving in 45 states, it's a little concerning,” said Emily Olsen, a health statistician in the CDC's Division of Adolescent and School Health and the report's lead author. Past studies conducted in single states have found anywhere from one quarter to almost three quarters of teenagers text while driving, the study team wrote Monday in Pediatrics. To get a more nationally representative picture, Olsen and her colleagues analyzed responses to the CDC's annual youth risk survey. On the 2011 survey, conducted in public and private schools across the country, 8,505 high school students ages 16 and older were asked about potentially dangerous driving behaviors they had engaged in over the past month. Just under 45 percent had texted while driving at least once during that span, and close to 12 percent of teens said they texted behind the wheel every day. Although the study team didn't measure how cell phone use may have affected safety in the car, past research shows that texting while driving can slow reaction times and impair a driver's ability to stay in one lane. The more frequently students reported texting and driving, the more likely they were to also answer “yes” to other risky behaviors, the researchers found. For example, 3 percent of teens who didn't text at the wheel had recently driven after drinking alcohol. That compared to 19 percent who reported texting and driving at least once in the past month and 34 percent who said they texted in the car daily. Likewise, 19 percent of non-texters had ridden in a car with another driver who had been drinking, versus 33 percent of high school students who reported texting and driving themselves. “It's concerning that kids are participating in these multiple behaviors, either while they're driving or while they're a passenger,” Olsen said. “Each one of these things is quite dangerous (on its own).” Jessica Mirman, who has studied teen motor vehicle cell phone use at Children's Hospital of Philadelphia's Center for Injury Research and Prevention, agreed. “That just really highlighted that as far as prevention goes, we really need something comprehensive,” Mirman, who wasn't involved in the new research, said. “It's not just about texting. It's not just about drinking.” Olsen said parents have the best chance of being able to curb unsafe activities in the car by continuing to talk with their children about safe driving even after they have their license. Teens, she pointed out, are already more likely to get into - and have trouble getting out of - dangerous situations on the road, due to their inexperience. “Anything that takes their attention away from the task of driving, it can wait,” she said. Parents who are worried about their teens' driving behavior should reach out to their pediatrician or a school counselor, Mirman advised, as that risk-taking might reflect other underlying problems.source : http://www.foxnews.com/health/2013/05/13/teen-texting-at-wheel-tied-to-more-driving-risks/
A Mountlake Terrace, Wash., teenager accidentally swallowed a piece of grill brush wire while eating, which ultimately got stuck in his intestines “stabbing him from the inside out,” The Seattle Times reported. …