First observation of a human HAT, key proteins in numerous pathologies — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/02/140211113835.htm
Tag Archives: cell
New live-cell printing technology works like ancient Chinese woodblocking — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/02/140210161116.htm
Split decision: Stem cell signal linked with cancer growth — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/02/140202132339.htm
How DNA damage affects Golgi — the cell’s shipping department — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/01/140130121613.htm
Protocol developed to harvest mouse cell lines for melanoma research — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/01/140131130626.htm
Cracks in cellular transport system can be key to new generation of cancer therapies — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/01/140127092932.htm
New prostate cancer drugs may not target root cause of disease, scientists warn — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/01/140124110720.htm
New computer model may aid personalized cancer care — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/01/140124082354.htm
New computer model may aid personalized cancer care
Reporting in the journal Cell Reports, researchers combined several types of data from pre- and post-treatment biopsies of breast tumors to obtain a molecular picture of how the cancer evolved as a result of chemotherapy. “Better understanding of tumor evolution is key to improving the design of cancer therapies and for truly individualized cancer treatment,” said Kornelia Polyak, MD, PhD, a breast cancer researcher. The model was developed by Polyak and Franziska Michor, PhD, a computational biologist at Dana-Farber. …
Two proteins compete for one port on a growth factor; one promotes metastasis, the other blocks it
Such is the case with two proteins identified by scientists at The University of Texas MD Anderson Cancer Center that fit on to the same binding site on an important cellular growth factor receptor called FGFR2 with starkly different results. "There is competition for binding to FGFR2 and one of the two competitors, phospholipase Cγ1 (Plcγ1), will increase cancer cell metastasis. The other protein inhibits the opportunity for this to occur," said John Ladbury, Ph.D., professor of Biochemistry and Molecular Biology. …