The process of tumor invasion and metastasis factors, a large literature shows that, urokinase-type plasminogen activator (uPA system) and tumor closely related to humans, including leukemia are associated with a variety of tumors overexpressed uPA and uPAR such as breast cancer, liver cancer , colon cancer, lung cancer , bladder cancer, adenocarcinoma, and glioblastoma film… Read More »
Check the type of colon cancer (1) colonoscopy: the mirror made in 1963 and clinical application. Body length of the colon is divided into long-type endoscope (170 cm), medium (125 cm), short (90 cm): 3, since the mirror has been used in clinical disease of the colon and terminal ileum markedly diagnostic accuracy increased. Mirror… Read More »
Risk factors for colorectal cancer (1) family history. Adenocarcinoma of familial polyposis, can be cancerous after 40 years of age, 55 years almost 100% of the cancer, the disease is rare, accounting for only 1% of all colorectal cancer is about. Hereditary non-polyposis is caused by mutations in mismatch repair genes, accounting for 5% of… Read More »
Gross morphology of colon cancer is divided into categories in the following categories: (1) bulky: the cauliflower-like mass, broke into the intestine, the surface can be an early rupture, hemorrhage and necrosis associated with secondary infection. Most occurred in the cecum, ascending colon and rectum ampulla. This type of cancer, mostly well differentiated adenocarcinoma, not… Read More »
Colorectal polyps inspection (1) digital rectal examination examination: diagnosis of polyps in the lower rectum, digital rectal examination is essential. DRE can be touched round, pedunculated or sessile; smooth surface can be moved, soft and flexible mass, multiple polyposis, the palpable rectal cavity about the size of grapes, ranging from round shaped masses. that put… Read More »
Adenomatous polyps can be divided into three types, namely, tubular adenoma, villous adenoma and mixed adenoma. Adenomatous polyp type (1) tubular adenoma: the most common, accounting for adenomatous the 80% interest. Occur in the rectum and sigmoid colon. Tubular adenoma spherical shape, smooth surface, may have congestion, punctate bleeding spots. Histological features of normal epithelial… Read More »
Specific clinical manifestations of cancer, straight colorectal cancer no obvious symptoms early, often in the rectal mucosa of a large mass appeared in the digital rectal examination has been able to reach the patient has no abnormal feeling, especially in no pain. Stimulate secretion but increased by straw film, while a small stool with mucus… Read More »
Treatment of advanced colorectal cancer (1) High-dose preoperative radiotherapy: the implementation of high-dose preoperative radiation therapy, can greatly improve the 5-year survival rate and decrease the local stage and recurrence, and need further exploration is how to split the radiation dose, and after radiotherapy How long is the best timing of surgery. Cancer treatment progress… Read More »
Tumor tissue factor and thrombin, tissue factor can induce the generation of thrombin, activate platelets, to produce aggregation, and feedback to promote the aggregation of intravenous and eventually caused the agglutination of fibrin. Thrombin also mediates many cellular responses, including angiogenesis, cracking protein kinase receptor (protease-activated receptors, PARs) to trigger a series of signal transduction… Read More »
HPV infection in the process of tumor formation has a very important role in the virus now known to cause reproductive tract, respectively, upper respiratory and digestive tract tumors.Papillary carcinoma of the virus most closely with esophageal squamous cell carcinoma pathology, KJ Syrjanen, who was first discovered in 1982, they were observed in esophageal cancer… Read More »