Adjuvant systemic treatments aim to prolong survival Even if the breast cancer was completely removed in surgery, the tumour can come back. The risk of such a recurrence can be low, intermediate or high. Adjuvant systemic treatments including chemotherapy are used to lower the risk of recurrence and prolong survival. …
Julian Spallholz, a professor of nutritional sciences at Texas Tech University, has studied the effects of selenium on several types of cancer. His research on attaching selenium to the leading clinical chemotherapeutic monoclonal antibody for a type of breast cancer shows it can more effectively kill the cancer cells, he reports. About 20 percent of breast cancer patients have overexpressed growth receptors, known as Her2+ receptors, on the cancer cells, which cause uncontrolled tumor growth…
The procedure, conducted on Sept. 30 under the auspices of the Sanford Stem Cell Clinical Center at UC San Diego Health System and in collaboration with Neuralstem, Inc., a Maryland-based biotechnology firm, is the first of four in the Phase I clinical trial. …
Julian Spallholz, a professor of nutritional sciences at Texas Tech University, has studied the effects of selenium on several types of cancer. His research on attaching selenium to the leading clinical chemotherapeutic monoclonal antibody for a type of breast cancer shows it can more effectively kill the cancer cells, he reports…
Studies have shown that breast cancer patients treated with radiation therapy have improved local-regional recurrence, and breast cancer-specific survival after breast-conserving surgery and overall survival (OS) after mastectomy. Long-term follow-up of historic radiation therapy trials for breast cancer has demonstrated a potential increase in cardiac mortality. However, these studies used earlier modes of radiation therapy including Cobalt and orthovoltage radiotherapy, and did not employ CT-based planning, which allows for greater cardiac avoidance. Three recent studies suggest that cardiac mortality has not been greater for patients treated for left-sided breast cancer since the 1980s, when techniques allowing for greater cardiac avoidance became more commonplace[1-3]. …
“Exposure to artificial light leads to a significantly higher risk for developing breast cancer,” said Chunla He, a biostatistics graduate student in the UGA College of Public Health. “To decrease the use of artificial light, people should avoid working at night and implement earlier bed times.” Her research, published in the International Archives of Occupational and Environmental Health, examined key studies that included risk factors for developing breast cancer. “A large body of related research about circadian rhythms and breast cancer exists,” He said. “However, these studies are inconsistent and have a variety of limitations.” Under the mentorship of Sara Wagner Robb, assistant professor of epidemiology in the College of Public Health, He turned to previous studies to see what the research revealed. …
The variant, a difference in just one of the three billion “letters” in the human genome known as a single-nucleotide polymorphism (SNP), originates from indigenous Americans and confers significant protection from breast cancer, particularly the more aggressive estrogen receptor-negative forms of the disease, which generally have a worse prognosis. …
MicroRNAs are small intracellular RNA molecules that regulate gene expression. Therefore, they play important roles in various normal processes of the human body, such as embryogenesis, and the regulation of cell viability…
IGRT is the process of using frequent imaging, typically performed in the treatment room prior to radiation delivery, throughout a patient’s course of radiation therapy treatment to improve localization of the target and normal structures, which allows for more precise and accurate radiation delivery. IGRT is a common practice in both photon (traditional radiation therapy) and proton therapy to treat tumors close to sensitive structures and organs or in areas of the body prone to movement or change in shape. This study, “Practice patterns of photon and proton pediatric image guided radiation treatment: Results from an International Pediatric Research Consortium,” evaluates the use of IGRT in treatment planning for pediatric cancers in an international consortium comprised of seven institutions using either photon or proton therapy with dedicated pediatric expertise. Choosing optimal IGRT regimens that spare healthy tissue and organs is a particular concern for pediatric patients to help prevent potential late effects associated with the distribution of the radiation dose and the total radiation dose the patient receives. …
Mutations in the body’s cells randomly accumulate as part of the aging process, and most are harmless. For some people, genetic changes in blood cells can develop in genes that play roles in initiating leukemia and lymphoma even though such people don’t have the blood cancers, the scientists report Oct…