What are the causes of breast cancer

By | December 10, 2011

Causes of breast cancer, breast cancer is breast epithelial cells under a variety of carcinogenic factors, the occurrence of the gene mutation, resulting in uncontrolled cell proliferation. Because the biological behavior of cancer cells has changed, showing a disordered, unlimited malignant proliferation. It is the histological manifestation of the large number of naive cells to proliferate indefinitely and crowded into a group-like disorder, extrusion and erosion damage to the surrounding normal tissue, destruction of normal breast tissue structure.
Mutation in breast cells after the loss of the normal cell characteristics, organizational structure, disorder, loosely connected cells, cancer cells can easily fall off free, spread over the body such as blood or lymph, the early formation of distant metastases to the breast cancer clinical increased very difficult to cure. The transfer of the body of important organs such as lung metastasis, brain metastasis, bone metastasis and so will be a direct threat to human life, it is a serious threat to human life breast cancer. The following are the causes of breast cancer:
1. Breast ovarian function by ovarian hormones in the physiological regulation of estrogen to stimulate breast development is the basic condition is one of the prerequisites for cancer. Some studies that menarche less than 12 years of age, the relatively high incidence of breast cancer; underwent bilateral oophorectomy in women with breast cancer rare, indicating the occurrence of ovarian function and breast cancer causation.
2. Childbearing and breastfeeding single women than married women with breast cancer for many, marriage is not fertile, birth or breast-feeding breast-feeding but not too short, a higher incidence of breast cancer. Breast-feeding may delay the reconstruction of post-partum ovulation and menstruation, and to improve the development of breast tissue.
3. Familial aggregation of family members and relatives who have breast cancer, the risk of breast cancer 2-3 times higher than normal.
4. Benign breast disease, benign breast tumor the chance of breast cancer higher than normal. Lobular hyperplasia or breast fibroadenoma in patients with increased risk of breast cancer, some benign diseases can increase susceptibility to cancer or cancer-promoting substances.
5. Radiotherapy and breast cancer related to ionizing radiation, the risk increases with radiation dose. Atomic bombing of Nagasaki and Hiroshima at the time of the survivors, breast cancer incidence increasing trend.
6. Diet and obesity in older women, weight gain increased incidence of breast cancer.Causes of breast cancer in recent years, research indicates that changes in diet, especially fat diet, can change the endocrine environment, strengthen or extend the estrogen stimulation of mammary epithelial cells and increase the risk of breast cancer. Generally believed that human malignant tumors, 1 / 3 of diet-related weight gain in women after menopause may be important risk factors for breast cancer.

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