Features and diagnosis of acute leukemia

By | December 17, 2011

Features and diagnosis of acute leukemia, acute leukemia onset in two cases, often abrupt onset of high fever, progressive anemia, bleeding or sore and obviously as the first symptom, but often slow onset while those longer fatigue, poor appetite, shortness of breath and other symptoms after the start of labor. But the case of the slow onset of the disease once the symptoms and the rapid onset often worsened while 9 cases similar to the acute onset were more common in acute lymphoblastic, acute lymphoblastic leukemia, a rare early performance, slow onset were mainly seen in the emergency Fei Lin. Various types of acute leukemia are often common clinical manifestations: a result of normal blood cells decreased. Lead to anemia, hemorrhage, secondary infection and fever; due to extensive infiltration of leukemia cells in organs of the organizations lead to liver, spleen, lymph nodes and other organs dysfunction.
(1) anemia, the symptoms of anemia in patients with acute leukemia often appear too early and severe, showing progressive development, and accompanied by dizziness, palpitations, weakness, shortness of breath. Recognition of about 60% is significantly lower hemoglobin
(2) the performance of the teeth with bleeding, nasal, oral mucosal bleeding and vomiting blood, blood in the stool, skin, mucous membranes or purple blood spots breaking epilepsy, increased menstrual or menstrual extension and so on. Thrombocytopenia, bleeding is the main reason for acute leukemia, leukemia cell infiltration, chemotherapy drugs stimulate the destruction of toxins and infection can damage endothelial cells, leading to a wide range of local hemorrhage.
(3) characteristics and diagnosis of acute infection and fever in adults with acute leukemia who fever as an early manifestation of fever often accompanied by infection, stomatitis common. Gum inflammation, or severe angina can occur when the ulcers, and even necrosis, Hong service next week or rectal inflammation and swelling are very common lung infection, severe sepsis and bacteremia infections often lead to high fever and the infection focus is sometimes difficult to find, but often suggestive of acute febrile infection.
(4) lymph nodes and hepatosplenomegaly is common in cervical lymph nodes, and brought under the armpits, groin, etc., generally soft or medium hardness, multi no adhesion, pain or occasional pain. Lymph nodes the highest incidence of acute lymphoblastic, acute Feilin rare, but children up to 609 hairs. Often mild to moderate acute hepatomegaly, splenomegaly are common. Splenomegaly were mainly seen in blast crisis CML, hairy cell leukemia and prolymphocytic leukemia, acute lymphoblastic splenomegaly were rare there.
(5) the performance of bone and joint pain common acute lymphoblastic, chronic myeloid blast crisis often significant bone pain, severe persistent may burst was feeling. Lower sternal tenderness are also common. Department of intramedullary bone pain causes abnormal proliferation of leukemia cells induced by the pressure increased, subperiosteal infiltration, degeneration of bone marrow protein network hardware, bone infarct, and rare osteolytic myeloid sarcoma. Visible joint swelling or pain in children.
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