Tag Archives: virus

Number of cancer stem cells might not predict outcome in HPV-related oral cancers

The researchers investigated cancer stem cell numbers in oral cancers associated with human papillomavirus (HPV) and in oral cancers not associated with the virus. Typically, patients with HPV-positive oral cancer respond better to therapy and have a more promising prognosis than patients with HPV-negative tumors. The latter are usually associated with tobacco and alcohol use…

T-cell research sheds light on why HIV can persist despite treatment

The paper, titled "HIV-1 Persistence in CD4+ T-Cells with Stem Cell-Like Properties," provides evidence that a particular T-cell type may help researchers better understand why HIV can persist despite treatment. Zurakowski’s co-authors include Mathias Lichterfeld, the paper’s lead author, and researchers from Massachusetts General Hospital (MGH); Ragon Institute of MGH, the Massachusetts Institute of Technology and Harvard University; the First Affiliated Hospital of China Medical University; Brigham and Women’s Hospital; and Howard Hughes Medical Institute. Zurakowski explained that HIV treatments do not kill infected cells…