Promising prognostic biomarker candidates for ovarian cancer uncovered
The first study establishes an association of this often-deadly cancer with the immune system and clarified the role of a class of immunogenic tumor antigens known as cancer testis (CT) antigens, and the second reports new evidence that certain molecular interactions influence ovarian cancer prognosis. In context with recent evidence that the immune system can potently inhibit the growth of cancer cells, these novel findings may enable development of a new strategy for identifying those patients most likely to benefit from particular targeted therapies. “There is a lot of interest right now in what to do with the human genome,” says Kevin Eng, PhD, an Assistant Professor of Oncology in the Department of Biostatistics and Bioinformatics at RPCI who was first author on both studies. …