Researchers identify priority targets for immunotherapy in epithelial ovarian cancer
Epithelial ovarian cancer is the most lethal gynecologic cancer in women and has a relapse rate of 85%. “The MAGE family of proteins is part of a class of CTAs that may serve as a target for directed immunotherapy in ovarian cancer and other types of cancer,” said senior author Kunle Odunsi, MD, PhD, FRCOG, FACOG, M. Steven Piver Professor of Gynecologic Oncology and Executive Director of the Center for Immunotherapy at RPCI. “To achieve the important goal of tumor-directed immunity for ovarian cancer immunotherapy, it is critical to determine the extent to which this family of CTA molecules is expressed in these tumor cells.” Dr…