Tag Archives: queen

Antihormone therapy anastrozole may provide new option for breast cancer prevention

About 80 percent of women diagnosed with breast cancer in the United States each year have tumors with high levels of hormone receptors. These tumors are fueled by the hormone estrogen. Anastrozole is a drug that prevents the body from making estrogen, and it has been used to treat postmenopausal women with hormone receptor-positive breast cancer for more than 10 years. "We initiated the International Breast Cancer Intervention Study II (IBIS-II) Prevention trial to investigate whether anastrozole can be used effectively to prevent breast cancer," said Jack Cuzick, Ph.D., chairman of the IBIS-II Steering Committee. …

Molecule common in some cancers, rheumatoid arthritis leads to potential therapy for both

The study, published in Oncotarget, was led by investigators at Georgetown University Medical Center (GUMC), and included collaborators from Harvard and Columbia Universities, Mayo Clinic and Queen’s University in Belfast, Northern Ireland. "Our findings suggest that cadherin-11 is important for cancer progression as well as rheumatoid arthritis — for reasons we do not fully understand. …

Could sleeping stem cells hold key to treatment of aggressive blood cancer?

The finding offers the potential that these stem cells could somehow be turned back on, offering a new form of treatment for the condition, called Acute Myeloid Leukemia (AML). The work was led by scientists at Queen Mary, University of London with the support of Cancer Research UK’s London Research Institute…