Tag Archives: medical

Gene increases risk of breast cancer to one in three by age 70 — ScienceDaily

In a study run through the international PALB2 Interest Group a team of researchers from 17 centres in eight countries led by the University of Cambridge analysed data from 154 families without BRCA1 or BRCA2 mutations, which included 362 family members with PALB2 gene mutations. The effort was funded by the European Research Council, Cancer Research UK and multiple other international sources. Women who carried rare mutations in PALB2 were found to have on average a 35% chance of developing breast cancer by the age of seventy. However, the risks were highly dependent on family history of breast cancer where carriers with more relatives affected by breast cancer, were at higher risk. …

Prostate cancer screening reduces deaths by a fifth: Large, long-term European trial — ScienceDaily

Despite this new evidence for the effectiveness of prostate-specific antigen (PSA) testing to reduce mortality, doubts as to whether the benefits of screening outweigh the harms remain, and routine PSA screening programmes should not be introduced at this time, conclude the authors. The European Randomised study of Screening for Prostate Cancer (ERSPC) began in 1993 to determine whether screening men for PSA reduces deaths from prostate cancer. …

Prostate cancer screening reduces deaths by a fifth: Large, long-term European trial

Despite this new evidence for the effectiveness of prostate-specific antigen (PSA) testing to reduce mortality, doubts as to whether the benefits of screening outweigh the harms remain, and routine PSA screening programmes should not be introduced at this time, conclude the authors. The European Randomised study of Screening for Prostate Cancer (ERSPC) began in 1993 to determine whether screening men for PSA reduces deaths from prostate cancer. …

PET/CT using leucocytes may detect infection in acute pancreatitis patients

Acute pancreatitis (AP) is a sudden inflammation of the pancreas. It can have severe complications and high mortality despite treatment. While mildcases of AP are often successfully treated with conservative measures, such as nil per os (NPO) and aggressive intravenous fluid rehydration, severe cases may require admission to the intensive care unit or even surgery to deal with complications of the disease process. Early detection of infection in AP affects the choice of treatment and clinical outcome…

Shingles vaccine remains effective after chemotherapy

Researchers examined the electronic health records of more than 21,000 Kaiser Permanente patients in Southern California who were 60 years of age and older and received chemotherapy between January 2007 and December 2012. Researchers found that those patients who were previously vaccinated with zoster vaccine were 42 percent less likely to develop shingles following chemotherapy. In addition, no vaccinated patients underwent hospitalization for shingles, while six unvaccinated patients were hospitalized with the disease, according to the study…

Many cancer survivors smoke years after diagnosis

“We need to follow up with cancer survivors long after their diagnoses to see whether they are still smoking and offer appropriate counseling, interventions, and possible medications to help them quit,” said Lee Westmaas, PhD, director of tobacco research at the American Cancer Society (ACS) and lead author of the study. Roy Herbst, MD, PhD, chief of medical oncology at Yale University and chair of the AACR Tobacco and Cancer Subcommittee, who was not involved with the study, said in an interview that the findings illustrate the scope of the problem. “Smoking can cause new mutations among cancer survivors that can lead to secondary and additional primary cancers. …

Patient navigation may aid in breast cancer treatment in high-risk populations — ScienceDaily

Using data from a previously published, multi-center study funded by the National Cancer Institute, researchers aimed to identify the possible benefits of assigning patient navigators to women recently diagnosed with breast cancer. According to the results, women were more likely to start recommended treatment when assisted by one of these trained specialists. For example, they were more likely to start hormonal therapy, which is considered the gold standard in treatment for certain types of breast cancer. Naomi Ko, MD, MPH, instructor of medicine in the Section of Hematology Oncology at Boston University School of Medicine and a practicing breast oncologist at Boston Medical Center, stresses the need for further investigation…

Model of viral lifecycle could help in finding a cure for hepatitis B

In a paper published in the journal Proceedings of the National Academy of Sciences, Sangeeta Bhatia of MIT and Charles Rice of Rockefeller University describe using microfabricated cell cultures to sustain hepatitis B virus in human liver cells, allowing them to study immune responses and drug treatments. …