Tag Archives: journal

More than 1.5 million cancer deaths averted during 2 decades of dropping mortality

Each year, the American Cancer Society compiles the most recent data on cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute and the Centers for Disease Control and Prevention, and mortality data from the National Center for Health Statistics. The data are disseminated in two reports: Cancer Statistics 2015, published in CA: A Cancer Journal for Clinicians, and its companion, consumer-friendly publication, Cancer Facts & Figures 2015. The reports also estimate the number of new cancer cases and deaths expected in the United States in the current year. Largely driven by rapid increases in lung cancer deaths among men as a consequence of the tobacco epidemic, the overall cancer death rate rose during most of the 20th century, peaking in 1991. …

More than 1.5 million cancer deaths averted during 2 decades of dropping mortality — ScienceDaily

Each year, the American Cancer Society compiles the most recent data on cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute and the Centers for Disease Control and Prevention, and mortality data from the National Center for Health Statistics. The data are disseminated in two reports: Cancer Statistics 2015, published in CA: A Cancer Journal for Clinicians, and its companion, consumer-friendly publication, Cancer Facts & Figures 2015. The reports also estimate the number of new cancer cases and deaths expected in the United States in the current year. …

Cancer treatment potential discovered in gene repair mechanism

If the laboratory findings are supported by tests in animal models, the breakthrough could hold the promise of increasing the effectiveness of radiation and chemotherapy in shrinking or even eliminating tumors. The key is to build up a “good” protein — p53-binding protein 1 (53BP1) — so that it weakens the cancer cells, leaving them more susceptible to existing cancer-fighting measures. The breakthrough detailed appeared in the Nov. 24 online edition of the journal PNAS (Proceedings of the National Academy of Sciences). …

Whole-genome sequencing can successfully identify cancer-related mutations — ScienceDaily

This is the first study that has used whole-genome sequencing to evaluate a series of 258 cancer patients’ genomes to improve the ability to diagnose cancer-predisposing mutations. The study is published online in the journal EBioMedicine. “Whole-genome sequencing is a new genetic tool that can determine more of a person’s DNA sequence than ever before. Our results show that nearly 90 percent of clinically identified mutations were confidently detected and additional cancer gene mutations were discovered, which together with the decreasing costs associated with whole-genome sequencing means that this method will improve patient care, as well as lead to discovery of new cancer genes,” said Dr…

Diagnostic screening: Microwave imaging of the breast may be better and safer

A better, cheaper, and safer way to look for the telltale signs of breast cancer may be with microwaves, said Neil Epstein, a NSERC CREATE I3T postdoctoral fellow at the University of Calgary in Canada. Epstein and his colleagues–engineering professor Paul Meaney of Dartmouth College’s Thayer School of Engineering and Keith Paulsen, director of the Dartmouth Advanced Imaging Center and the Robert A. Pritzker Professor of Biomedical Engineering and Professor of Radiology at the Geisel School of Medicine at Dartmouth College — describe just such a microwave imaging system in the current issue of the journal Review of Scientific Instruments, from AIP Publishing…

Important gene interaction defined that drives aggressive brain cancer

In a study recently published in the journal Neuro-Oncology, a team of scientists led by Luni Emdad, M.B.B.S., Ph.D., and Paul B. Fisher, M.Ph., Ph.D., provided the first evidence of an important link between a specific microRNA, miR-184, and a cancer promoting gene, SND1, in the regulation of malignant glioma. miR-184 is known to suppress tumor development by regulating a variety of genes involved in cancer growth, while SND1 has been shown to play a significant role in the development of breast, colon, prostate and liver cancers. Through a variety of preclinical experiments, the team demonstrated that increasing the expression of miR-184 slows the growth and invasive characteristics of glioma cells through direct regulation of SND1. …

Early adoption of robotic surgery leads to organ preservation for kidney cancer patients

Researchers from NYU Langone Medical Center and elsewhere, publishing online December 11 in the journal Medical Care, report that by 2008, hospitals that had adopted robotic surgery at the start of the current century (between 2001 and 2004) performed partial nephrectomies in 38% of kidney cancer cases compared to late adopters (2005 to 2008) who performed partial nephrectomies only 24% of the time. Partial nephrectomy, the removal of a section of the kidney as opposed to the removal of the entire organ, is preferred over total nephrectomy because it can achieve similar outcomes in cancer while avoiding the long-term risks associated with total kidney removal, such as cardiovascular disease, chronic kidney failure and premature death…

HPV vaccine, riskier sexual activity not linked, Canadian researchers say

There are concerns the vaccine, which guards against four types of the HPV shown to cause cervical cancer and anogenital warts, may give girls a false sense of security about contracting sexually transmitted infections (STIs) and lead them to engage in riskier sexual activity. “These findings suggest fears of increased risky sexual behaviour following HPV vaccination are unwarranted and should not be a barrier to vaccinating at a young age,” says Dr. Smith, the lead author on the study that was published in the Canadian Medical Association Journal. This study looked at a cohort of 260,493 girls, of whom about half (128,712) were eligible for Ontario’s publicly funded, school-based HPV vaccination program during the first two school years it was offered (2007-08 and 2008-09). …