Tag Archives: individualized

New tool aids stem cell engineering for medical research

“This free platform has a broad range of uses for all types of cell-based investigations and can potentially offer help to people working on all types of cancer,” says Hu Li, Ph.D., investigator in the Mayo Clinic Center for Individualized Medicine and Department of Molecular Pharmacology & Experimental Therapeutics, and co-lead investigator in the two works. “CellNet will indicate how closely an engineered cell resembles the real counterpart and even suggests ways to adjust the engineering.” The network biology platform contains data on a wide range of cells and details on what is known about those cell types. Researchers say the platform can be applied to almost any study and allows users to refine the engineering process. In the long term, it should provide a reliable short cut to the early phases of drug development, individualized cancer therapies, and pharmacogenetics. …

Faster tumor analysis software developed, speeds cancer discoveries — ScienceDaily

source : http://www.sciencedaily.com/releases/2014/02/140224171301.htm

Scientists propose breast cancer drug for bladder cancer patients

As with breast cancer, HER2 amplification in MPUC results in a faster growing form of cancer that spreads quickly and has a higher chance of recurrence. The hope is that combating this amplification with trastuzumab, a drug that is effective in HER2 positive breast cancers, will result in effective therapy against bladder cancer. "These findings show it is critical for pathologists to recognize this type of bladder cancer and that providers should be aware of and order the appropriate tests," says John Cheville, M.D., a Mayo Clinic pathologist and lead author of the study. …