Prostate specific antigen screening declines after 2012 USPSTF recommendations — ScienceDaily
source : http://www.sciencedaily.com/releases/2014/03/140313134253.htm
source : http://www.sciencedaily.com/releases/2014/03/140313134253.htm
source : http://www.sciencedaily.com/releases/2014/01/140129114500.htm
“Almost two-thirds (64.5%) of women who have had hysterectomies reported having recent Pap tests,” said Deanna Kepka, PhD, MPH, co-author of the study, a Huntsman Cancer Institute (HCI) investigator, and assistant professor in the College of Nursing at the University of Utah. “And half (50.4%) of women over 65 who have no cervical cancer history also reported a recent Pap test. This represents 14 million women in the United States receiving an unnecessary procedure.” Because the risk of developing this slow-growing cancer is very small at such a late stage in life, Pap tests do not benefit women over age 65 who have no history of cervical cancer or pre-cancerous conditions…
In papers published in the American Journal of Public Health and the Bulletin of the History of Medicine, Aronowitz, professor and chair of Penn’s Department of History and Sociology of Science, characterizes the events then and screenings for prostate-specific antigen, or PSA, in more recent years as "part of one continuous story of how medical and lay people came to believe in the efficacy of population screening followed by aggressive treatment without solid supporting scientific evidence." "This is a call to reflection about how we deal with medical knowledge production and medical technological innovation," Aronowitz said. …
Published in the Oct. 4 issue of the journal Cancer, the study also found considerable geographic variation in the cost of prostate cancer screening…
That’s the finding of a new study published today in JAMA Internal Medicine that examined both web-based and printed tools aimed at helping men make informed decisions about PSA testing. In May 2012, the US Preventive Services Task Force recommended against screening all men for prostate cancer. Most health professional groups recommend shared decision making so that men can understand the limitations of screening before making a decision about being tested. …
The U.S. Preventive Services Task Force (USPTF) recommends that middle-aged men not receive the prostate-specific antigen test (PSA) because research has shown that the benefits of testing do not outweigh the risks, which include false positive results. More than three quarters of the men who participated in the survey said they were not aware of the new recommendation, said Linda Squiers, Ph.D., senior health communication scientist at RTI International in Rockville, MD, and lead author of the study…
Spherical nanoparticles labeled with red or green dye shift their shapes and accumulatte into netlike structures when they encounter a protease secreted by some kinds of cancerous tumors (Click on image for larger view). Targeting treatments specifically to cancerous or other diseased cells depends on some means of accumulating high levels of a drug or other therapeutic agent at the specific site and keeping it there. Most efforts so far depend on matching a piece of the drug-delivering molecule to specific receptors on the surface of the target cell. …
Doctors should regularly screen babies and young children for delays in motor skill development - including trouble sitting, standing and speaking - at well-child visits, pediatricians said today. In a clinical report, an American Academy of Pediatrics (AAP) panel said diagnosing and treating those problems early on may ultimately improve kids' outlook and help families gain additional support. “Identifying children with delays and motor abnormalities, theoretically or hopefully would set them on a better trajectory,” said Meghann Lloyd, who studies motor development at the University of Ontario Institute of Technology in Oshawa, Canada. Lloyd, who was not involved in the new report, called it “a really big step forward for the field.” Dr. Garey Noritz and colleagues on the AAP's neuromotor screening expert panel lay out the skills that a child should have developed by office visits at ages 9, 18, 30 and 48 months. For example, a 9-month-old baby should be able to roll to both sides, sit well without support and grasp objects. At 18 months, that child should be able to walk, sit and stand on its own. Pediatricians should also ask parents open-ended questions about their child's development and watch the child play for signs of delays or loss of motor skills at well-child visits, the panel said. On a general exam, it recommended that doctors measure head size and look at children's muscle tone, reflexes and eye movements. The U.S. Preventive Services Task Force, a government-backed expert panel, said in 2006 there wasn't enough evidence to recommend for or against screening instruments designed to detect speech and language delays in young kids. The task force does not have screening recommendations for motor delays in general. “The AAP… recognized that we as a profession weren't necessarily doing a good job screening for motor problems,” Noritz, from Nationwide Children's Hospital in Columbus, Ohio, told Reuters Health. Cerebral palsy and muscular dystrophy are two of the most common motor-related diseases and could both be picked up and treated earlier than they typically are now, according to Noritz. He said families often refer to the “diagnostic odyssey” involved in getting a definitive diagnosis for a sick child. “We're hoping that people can get to a specialist more quickly and thus get diagnosed more quickly, but that primary care clinicians at the same time as they're looking for a diagnosis, will refer (kids) to therapy,” he said. Promoting movement There is normal variation in how kids develop, Lloyd said - so if a child is a couple of months late to walk, for example, parents shouldn't be overly concerned. But longer delays, or combinations of multiple motor problems, are a good reason for a visit to the pediatrician, she told Reuters Health. “Other types of movements that don't seem right, like a tremor or a rigidity or some sort of repetitive motor movement would be another red flag for me,” Lloyd added. Typical motor delays that aren't a result of more serious underlying conditions are treated with physical or occupational therapy. Parents can bring their children to an early movement program such as Kindergym to promote development of motor skills, Lloyd said, regardless of other treatments and whether or not they are delayed. Having poor motor skills in general “sets you on a trajectory for low levels of physical activity, which of course is related to obesity,” she said. “The prevention of these delays or the promotion of motor ability can actually impact your health for your lifespan.”source : http://www.foxnews.com/health/2013/05/28/check-young-kids-for-motor-delays-pediatricians-suggest/
Cells in the human body do not function in isolation. Living cells rely on communication with their environment — neighboring cells and the surrounding matrix — to activate a wide range of cellular functions, including reproduction of new cells, differentiation of stem cells into distinct cell types, cell adhesion, and migration of white blood cells to fight bodily infections. This cellular communication occurs on the molecular level and it is reciprocal: a cell receives cues from and also transmits function-activating cues to its neighbors…