Vitamin C can kill drug-resistant TB
The study was published today in the online journal Nature Communications. TB is caused by infection with the bacterium M. tuberculosis. …
The study was published today in the online journal Nature Communications. TB is caused by infection with the bacterium M. tuberculosis. …
Too little sleep increases the risk of car crashes for young drivers, a new study confirms. In the study, drivers ages 17 to 24 who reported sleeping six or fewer hours per night were about 20 percent more likely to be involved in a car crash over a two-year period, compared with those who slept more than six hours a night. Car crashes among the sleep-deprived were more likely to occur between 8 p.m. and 6 a.m. than at other hours. The findings held even after the researchers took into account factors that affect people's risk of a car crash, such as age, the number of driving hours per week, risky driving behavior such as speeding and a history of car crashes. Sleep deprivation is known to be a risk factor for car crashes it's estimated that drowsy driving is responsible for 20 percent of all car crashes in the United States, the researchers say. However, most studies to date have not focused on young people. Young drivers should be a focus of education efforts to prevent drowsy driving “because this group experiences more impairment in alertness, mood and physical performance compared with older age groups with similar sleep deprivation,” the researchers said. The new study involved more than 19,000 young, newly licensed drivers living in New South Wales, Australia, who answered questions about their sleep habits, including how many hours they slept on weeknights and weekends. Researchers then tracked the participants for two years, and obtained police reports to document car crashes. Among drivers who reported getting six or fewer hours of sleep a night, 9.4 percent were involved in a crash, compared with 6.9 percent of those who reported more than six hours of sleep a night. The new findings “may help increase awareness of the impact of reduced sleep hours on crash risk and highlight subgroups of young drivers and times of day for targeted intervention,” the researchers write in the May 20 issue of the journal JAMA Pediatrics. The researchers noted that participants were only asked about their sleep habits once during the study, and the exact number of hours participants slept on the day before they were involved in a crash is not known. Follow Rachael Rettner @RachaelRettner. Follow MyHealthNewsDaily @MyHealth_MHND, Facebook & Google+. Originally published on LiveScience.Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.source : http://www.foxnews.com/health/2013/05/21/sleep-deprived-teen-drivers-more-likely-to-crash/
Do your kids love chocolate milk? It may have more calories on average than you thought. Same goes for soda. Until now, the only way to find out what people in the United States eat and how many calories they consume has been government data, which can lag behind the rapidly expanding and changing food marketplace. Researchers from the University of North Carolina at Chapel Hill are trying to change that by creating a gargantuan map of what foods Americans are buying and eating. Part of the uniqueness of the database is its ability to sort one product into what it really is - thousands of brands and variations. Take the chocolate milk. The government long has long classified chocolate milk with 2 percent fat as one item. But the UNC researchers, using scanner data from grocery stores and other commercial data, found thousands of different brands and variations of 2 percent chocolate milk and averaged them out. The results show that chocolate milk has about 11 calories per cup more than the government thought. The researchers led by professor Barry Popkin at the UNC School of Public Health, are figuring out that chocolate milk equation over and over, with every single item in the grocery store. It's a massive project that could be the first evidence of how rapidly the marketplace is changing, and the best data yet on what exact ingredients and nutrients people are consuming. That kind of information could be used to better target nutritional guidelines, push companies to cut down on certain ingredients and even help with disease research. Just call it “mapping the food genome.” “The country needs something like this, given all of the questions about our food supply,” says Popkin, the head of the UNC Food Research Program. “We're interested in improving the public's health and it really takes this kind of knowledge.” The project first came together in 2010 after a group of 16 major food companies pledged, as part of first lady Michelle Obama's campaign to combat obesity, to reduce the calories they sell to the public by 1.5 trillion. The Robert Wood Johnson Foundation agreed to fund a study to hold the companies accountable, eventually turning to UNC with grants totaling $6.7 million. Aided by supercomputers on campus, Popkin and his team have taken existing commercial databases of food items in stores and people's homes, including the store-based scanner data of 600,000 different foods, and matched that information with the nutrition facts panels on the back of packages and government data on individuals' dietary intake. The result is an enormous database that has taken almost three years so far to construct and includes more detail than researchers have ever had on grocery store items - their individual nutritional content, who is buying them and their part in consumers' diets. The study will fill gaps in current data about the choices available to consumers and whether they are healthy, says Susan Krebs-Smith, who researches diet and other risk factors related to cancer at the National Cancer Institute. Government data, long the only source of information about American eating habits, can have a lag of several years and neglect entire categories of new types of products - Greek yogurt or energy drinks, for example. With those significant gaps, the government information fails to account for the rapid change now seen in the marketplace. Now more than ever, companies are reformulating products on the fly as they try to make them healthier or better tasting. While consumers may not notice changes in the ingredient panel on the back of the package, the UNC study will pick up small variations in individual items and also begin to be able to tell how much the marketplace as a whole is evolving. “When we are done we will probably see 20 percent change in the food supply in a year,” Popkin says. “The food supply is changing and no one really knows how.” For example, the researchers have found that there has been an increase in using fruit concentrate as a sweetener in foods and beverages because of a propensity toward natural foods, even though it isn't necessarily healthier than other sugars. While the soda and chocolate milk have more calories on average than the government thought, the federal numbers were more accurate on the calories in milk and cereals. Popkin and his researchers are hoping their project will only be the beginning of a map that consumers, companies, researchers and even the government can use, breaking the data down to find out who is eating what and where they shop. Is there a racial divide in the brand of potato chips purchased, for example, and what could that mean for health? Does diet depend on where you buy your food - the grocery store or the convenience store…
The study — to appear online in JAMA Otolaryngology-Head & Neck Surgery — shows a strong correlation between brain dominance and the ear used to listen to a cell phone. More than 70% of participants held their cell phone up to the ear on the same side as their dominant hand, the study finds. Left-brain dominant people — who account for about 95% of the population and have their speech and language center located on the left side of the brain — are more likely to use their right hand for writing and other everyday tasks. Likewise, the Henry Ford study reveals most left-brain dominant people also use the phone in their right ear, despite there being no perceived difference in their hearing in the left or right ear…
In the new psychiatric manual of mental disorders, grief soon after a loved one's death can be considered major depression. Extreme childhood temper tantrums get a fancy name. And certain “senior moments” are called “mild neurocognitive disorder.” Those changes are just some of the reasons prominent critics say the American Psychiatric Association is out of control, turning common human problems into mental illnesses in a trend they say will just make the “pop-a-pill” culture worse. Says a former leader of the group: “Normal needs to be saved from powerful forces trying to convince us that we are all sick.” At issue is the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders, widely known as the DSM-5. The DSM has long been considered the authoritative source for diagnosing mental problems. The psychiatric association formally introduces the nearly 1,000-page revised version this weekend in San Francisco. It's the manual's first major update in nearly 20 years, and a backlash has taken shape in recent weeks: - Two new books by mental health experts, “Saving Normal” and “The Book of Woe,” say the world's most widely used psychiatric guide has lost credibility. - A British psychologists' group is criticizing the DSM-5, calling for a “paradigm shift” away from viewing mental problems as a disease. An organization of German therapists also attacked the new guide. - Even the head of the U.S. National Institute of Mental Health complained that the book lacks scientific validity. This week, the NIMH director, Dr. Thomas Insel, tried to patch things up as he and the psychiatrists group issued a joint statement saying they have similar goals for improving the diagnosis and treatment of mental illness. The manual's release comes at a time of increased scrutiny of health care costs and concern about drug company influence over doctors. Critics point to a landscape in which TV ads describe symptoms for mental disorders and promote certain drugs to treat them. “Way too much treatment is given to the normal `worried well' who are harmed by it; far too little help is available for those who are really ill and desperately need it,” Dr. Allen Frances writes in “Saving Normal.” He is a retired Duke University professor who headed the psychiatry group's task force that worked on the previous handbook. He says the new version adds new diagnoses “that would turn everyday anxiety, eccentricity, forgetting and bad eating habits into mental disorders.” Previous revisions were also loudly criticized, but the latest one comes at a time of soaring diagnoses of illnesses listed in the manual - including autism, attention deficit disorder and bipolar disorder - and billions of dollars spent each year on psychiatric drugs. The group's 34,000 members are psychiatrists - medical doctors who specialize in treating mental illness. Unlike psychologists and other therapists without medical degrees, they can prescribe medication. While there has long been rivalry between the two groups, the DSM-5 revisions have stoked the tensions. The most contentious changes include: - Diagnosing as major depression the extreme sadness, weight loss, fatigue and trouble sleeping some people experience after a loved one's death. Major depression is typically treated with antidepressants. - Calling frequent, extreme temper tantrums “disruptive mood dysregulation disorder,” a new diagnosis. The psychiatric association says the label is meant to apply to youngsters who in the past might have been misdiagnosed as having bipolar disorder. Critics say it turns normal tantrums into mental illness. - Diagnosing mental decline that goes a bit beyond normal aging as “mild neurocognitive disorder.” Affected people may find it takes more effort to pay bills or manage their medications. Critics of the term say it will stigmatize “senior moments.” - Calling excessive thoughts or feelings about pain or other discomfort “somatic symptom disorder,” something that could affect the healthy as well as cancer patients. Critics say the term turns normal reactions to a disease into mental illness. - Adding binge eating as a new category for overeating that occurs at least once a week for at least three months. It could apply to people who sometimes gulp down a pint of ice cream when they're alone and then feel guilty about it. - Removing Asperger's syndrome as a separate diagnosis and putting it under the umbrella term “autism spectrum disorder.” Dr. David Kupfer, chairman of the task force that oversaw the DSM-5, said the changes are based on solid research and will help make sure people get accurate diagnoses and treatment. Dr. Jeffrey Lieberman, the psychiatry association's incoming president, said challenging the handbook's credibility “is completely unwarranted.” The book establishes diagnoses “so patients can receive the best care,” he said, adding that it takes into account the most up-to-date scientific knowledge. But Insel, the government mental health agency chief, wrote in a recent blog posting that the guidebook is no better than a dictionary-like list of labels and definitions. He said he favors a very different approach to diagnosis that is based more on biological information, similar to how doctors diagnose heart disease or problems with other organs. Yet there's scant hard evidence pinpointing what goes wrong in the brain when someone develops mental illness. Insel's agency two years ago began a research project to create a new way to diagnose mental illness, using brain imaging, genetics and other evolving scientific evidence. That project will take years. The revisions in the new guide were suggested by work groups the psychiatric association assigned to evaluate different mental illnesses and recent research advances. The association's board of trustees decided in December which recommendations to include. Advocacy groups have threatened Occupy-style protests and boycotts at this week's meeting. “The psychiatric industry, allied with Big Pharma, have massively misled the public,” the Occupy Psychiatry group contends. Organizers include Alaska lawyer Jim Gottstein, who has long fought against overuse of psychiatric drugs. The new manual “will drastically expand psychiatric diagnosis, mislabel millions of people as mentally ill, and cause unnecessary treatment with medication,” says the website for the Committee to Boycott the DSM-5, organized by New York social worker Jack Carney. Committee member Courtney Fitzpatrick, whose 9-year-old son died seven years ago while hospitalized for a blood vessel disease, said she has joined support groups for grieving parents “and by no means are we mentally ill because we are sad about our kids that have died.” Gary Greenberg, a Connecticut psychotherapist and author of “The Book of Woe,” says pharmaceutical industry influence in psychiatry has contributed to turning normal conditions into diseases so that drugs can be prescribed to treat them. Many of the 31 task force members involved in developing the revised guidebook have had financial ties to makers of psychiatric drugs, including consulting fees, research grants or stock. Group leaders dismiss that criticism and emphasize they agreed not to collect more than $10,000 in industry money in the calendar year preceding publication of the manual.source : http://www.foxnews.com/health/2013/05/16/shrinks-critics-face-off-over-psychiatric-manual/
"Our findings are important because they provide new targets for the development of novel drugs to reduce heart disease risk in humans," said Laura Cox, Ph.D., a Texas Biomed geneticist. …
The Indian government announced Tuesday the development of a new low-cost vaccine proven effective against a diarrhea-causing virus that is one of the leading causes of childhood deaths across the developing world. The Indian manufacturer of the new rotavirus vaccine pledged to sell it for $1 a dose, a significant discount from the cost of the current vaccines on the market. That reduced price would make it far easier for poor countries to vaccinate their children against the deadly virus, health experts said. Rotavirus, spread through contaminated hands and surfaces, kills about half a million children across the world each year, 100,000 of them in India. At a conference Tuesday, the government announced that Phase III trials of Rotavac proved that it was safe as well as effective. The clinical trial of 6,799 infants at three sites in India showed the vaccine reduced severe cases of diarrhea caused by rotavirus by 56 percent during the first year of life. “The clinical results indicate that the vaccine, if licensed, could save the lives of thousands of children each year in India,” said Dr. K. Vijay Raghavan, the secretary of the Department of Biotechnology. The vaccine still needs to be licensed before it can be distributed in India and would require further approval by the World Health Organization before it could be distributed globally. Two other vaccines have proven effective against rotavirus, but they are significantly more expensive. The GAVI Alliance, which works to deliver vaccines to the world’s poor, negotiated a significant discount last year with GlaxoSmithKline and Merck, obtaining the rotavirus vaccines from those pharmaceutical companies for $2.50 a dose. The alliance has programs for delivering those vaccines in 14 countries and plans to expand them to 30 countries. Dr. Seth Berkley, the GAVI Alliance’s CEO, said the announcement Tuesday was “a big deal.” “The cheaper the price the more children you can immunize,” he said, adding that it will still take some time before the vaccine is approved for use. In addition, having a third manufacturer for the vaccines would ease supply shortages and could drive down the costs charged by the other manufacturers, he said. “That would make a big difference in terms of changing the marketplace,” he said. Diarrhea is the second leading cause of death among young children in the world after pneumonia. A study of 22,568 children at sites in seven African and south Asian countries that was published Monday in the medical journal The Lancet showed that rotavirus was the leading cause of moderate to severe diarrhea in children under the age of two. The new vaccine was developed from a weakened strain of the virus taken from a child hospitalized in New Delhi more than a quarter century ago. It was the result of a broad global partnership that included the government, the Indian company Bharat Biotech, the Bill and Melinda Gates Foundation and the U.S. Centers for Disease Control and Prevention, among many others. Those involved said the broad cooperation reduced research costs for the manufacturer and helped keep the vaccine inexpensive. “This public-private partnership is an exemplary model of how to develop affordable technologies to save lives,” Bill Gates, co-chair of the Gates Foundation, said in a statement.source : http://www.foxnews.com/health/2013/05/15/india-developing-cheap-vaccine-against-major-cause-diarrhea-deaths-in-kids/
Maybe you’ve heard that going supermarket shopping while hungry can cause you to spend more money. But, did you know that researchers at Cornell University found that hungry grocery shoppers are more apt to slip high-calorie foods into their cart? You can keep your food bill and your waistline in check simply by eating something before heading out to the grocery store. Grabbing a quick snack is probably easier on the weekend than it is after work when you are tired and your stomach is growling.  Choosing sugary candy and cookies from the office vending machine isn’t very diet-friendly nor will these hold you for long. Your best bet is to plan ahead and have a healthy, satisfying grab-and-go snack at the ready.  Here are some simple and tasty ideas: String cheese and grapes This refreshing sweet and salty combo could not be easier to pack. You can count on the natural sugar in the grapes to give you a nice energy boost while the protein in the cheese will digest slowly, keeping hunger in check until you sit down to dinner. Hummus and veggies Talk about smart substitutes! Let some baby carrots or sliced peppers answer the call for something crunchy, and by pairing them with hummus you have a light yet savory alternative to a bag of fatty deep-fried chips. Apple slices with peanut butter Simply cut an apple in half and core it. Then fill each cavity with a spoonful of creamy peanut butter. You get the fruity-nutty taste of a PB&J sandwich without the bread, plus a lot more tummy-filling fiber and protein.   Gorp!   This acronym stands for “good old raisins and peanuts,” but with some creative license it covers a healthy trail mix, too. Prepare a batch in minutes by mixing some dried fruit, almonds, high fiber cereal, and whole wheat pretzel sticks. Then fill zip-lock baggies with 1/2 cup portions.   Strawberries and Cream Start with a single serving of Greek yogurt and top it with juicy ripe sliced strawberries.  Greek yogurt is creamier than traditional yogurt and much higher in protein, which keeps you feeling full longer. The berries provide natural sweetness and tang and feel free to add a drizzle of sugar-free chocolate sauce over the strawberries to make this healthy snack seem more like a decadent dessert. For more tips, delicious high fiber meal plans, recipes, and proven ways to lose weight and look great, check out my new book The Miracle Carb Diet: Make Calories and Fat Disappear – with Fiber! Tanya Zuckerbrot MS, RD, is a registered dietitian in New York City and the bestselling author of The Miracle Carb Diet: Make Calories and Fat Disappear – with fiber, and The F-Factor Diet: Discover the Secret to Permanent Weight Loss.  Follow Tanya on Facebook, Twitter and LinkedIn, and visit her website Ffactor.com  source : http://www.foxnews.com/health/2013/05/14/snack-before-shop/
The study, reported in Cancer Cell, found that the EZH2 protein the drug agents inhibited is a powerful regulatory molecule in B-cells, and a key driver of cancer in these immune cells. The study’s lead investigator, Weill Cornell Medical College’s Dr. Ari Melnick, suggests that combining an EZH2 inhibitor with another related targeted therapy may offer a much improved treatment for follicular lymphoma, a cancer that currently has no cure, as well as a non-toxic alternative to chemotherapy for at least a third of diffuse large B-cell lymphomas. Because these two lymphomas account for 70 percent of adult lymphomas, Dr. …
Researchers have shown that when our skin is exposed to the sun’s rays, a compound is released in our blood vessels that helps lower blood pressure. The findings suggest that exposure to sunlight improves health overall, because the benefits of reducing blood pressure far outweigh the risk of developing skin cancer. …